Literature DB >> 29858669

Extended pelvic resection for rectal and anal canal tumors is a significant risk factor for perineal wound infection: a retrospective cohort study.

Ken Imaizumi1, Yuji Nishizawa2, Koji Ikeda1, Yuichiro Tsukada1, Takeshi Sasaki1, Masaaki Ito3.   

Abstract

PURPOSE: Perineal wound infection (PWI) rates are high after abdominoperineal resection (APR) and total pelvic exenteration (TPE). This study identified risk factors for PWI after surgery for anorectal tumors and examined the relationship between the surgical excision volume with the PWI degree.
METHODS: A retrospective review involving 135 patients who underwent surgical excision of anorectal tumors was performed. Superficial PWI included cellulitis and superficial dehiscence; deep PWI included major dehiscence, perineal abscess, and presacral abscess. The adjacent organ resection type was classified according to the dead space size formed by surgical excision.
RESULTS: Of the 135 patients, 119 underwent APR, and 16 underwent TPE. PWI occurred in 75 patients (superficial PWI, 44; deep PWI, 31). Adjacent organ resection was an independent risk factor for PWI. The cases with adjacent organ resection were classified into small-defect APR, large-defect APR, and TPE. Large-defect APR and TPE cases had significantly higher rates of deep PWI than APR cases without adjacent organ resection.
CONCLUSIONS: Adjacent organ resection involving the removal of one or more organs and that involving wide-range muscle resection are strong risk factors for deep PWI.

Entities:  

Keywords:  Abdominoperineal resection; Adjacent organ resection; Perineal wound infection; Total pelvic exenteration

Mesh:

Year:  2018        PMID: 29858669     DOI: 10.1007/s00595-018-1680-5

Source DB:  PubMed          Journal:  Surg Today        ISSN: 0941-1291            Impact factor:   2.549


  28 in total

Review 1.  An evolution of clinical application of inferior pedicle based rectus abdominis myocutaneous flap for repair of perineal defects after radical surgery for cancer.

Authors:  H S Shukla; Mallika Tewari
Journal:  J Surg Oncol       Date:  2010-09-01       Impact factor: 3.454

2.  Primary perineal wound closure after preoperative radiotherapy and abdominoperineal resection has a high incidence of wound failure.

Authors:  Kelli M Bullard; Judith L Trudel; Nancy N Baxter; David A Rothenberger
Journal:  Dis Colon Rectum       Date:  2005-03       Impact factor: 4.585

3.  Extended abdominoperineal resection with gluteus maximus flap reconstruction of the pelvic floor for rectal cancer.

Authors:  T Holm; A Ljung; T Häggmark; G Jurell; J Lagergren
Journal:  Br J Surg       Date:  2007-02       Impact factor: 6.939

4.  Utility of the omentum in pelvic floor reconstruction following resection of anorectal malignancy: patient selection, technical caveats, and clinical outcomes.

Authors:  Charles S Hultman; Matthew A Sherrill; Eric G Halvorson; Clara N Lee; John F Boggess; Michael O Meyers; Benjamin A Calvo; Hong J Kim
Journal:  Ann Plast Surg       Date:  2010-05       Impact factor: 1.539

5.  Outcomes of immediate vertical rectus abdominis myocutaneous flap reconstruction for irradiated abdominoperineal resection defects.

Authors:  Charles E Butler; A Ozlem Gündeslioglu; Miguel A Rodriguez-Bigas
Journal:  J Am Coll Surg       Date:  2008-02-11       Impact factor: 6.113

6.  Perineal reconstruction using pedicled vertical rectus abdominis myocutaneous flap (VRAM).

Authors:  Ahmed Touny; Haitham Othman; Sherif Maamoon; Samy Ramzy; Hamdy Elmarakby
Journal:  J Surg Oncol       Date:  2014-06-24       Impact factor: 3.454

7.  Evidence of the oncologic superiority of cylindrical abdominoperineal excision for low rectal cancer.

Authors:  Nicholas P West; Paul J Finan; Claes Anderin; Johan Lindholm; Torbjorn Holm; Philip Quirke
Journal:  J Clin Oncol       Date:  2008-06-09       Impact factor: 44.544

8.  Incisional negative pressure wound therapy decreases the frequency of postoperative perineal surgical site infections: a cohort study.

Authors:  Sami A Chadi; Biniam Kidane; Karen Britto; Muriel Brackstone; Michael C Ott
Journal:  Dis Colon Rectum       Date:  2014-08       Impact factor: 4.585

9.  Retrospective review of pelvic malignancies undergoing total pelvic exenteration.

Authors:  Maureen P Kuhrt; Ravi J Chokshi; David Arrese; Edward W Martin
Journal:  World J Surg Oncol       Date:  2012-06-15       Impact factor: 2.754

10.  Snapshot Study on the Value of Omentoplasty in Abdominoperineal Resection with Primary Perineal Closure for Rectal Cancer.

Authors:  Robin D Blok; Gijsbert D Musters; Wernard A A Borstlap; Christianne J Buskens; Wilhelmus A Bemelman; Pieter J Tanis
Journal:  Ann Surg Oncol       Date:  2017-12-12       Impact factor: 5.344

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  4 in total

1.  Tailored concept for the plastic closure of pelvic defects resulting from extralevator abdominoperineal excision (ELAPE) or pelvic exenteration.

Authors:  Julia Jackisch; Thomas Jackisch; Joerg Roessler; Anja Sims; Holger Nitzsche; Pia Mann; Sören Torge Mees; Sigmar Stelzner
Journal:  Int J Colorectal Dis       Date:  2022-06-25       Impact factor: 2.796

2.  Continuous Negative Pressure Drainage with Intermittent Irrigation Leaded to a Risk Reduction of Perineal Surgical Site Infection Following Laparoscopic Extralevator Abdominoperineal Excision for Low Rectal Cancer.

Authors:  Zhongbo Han; Chunxia Yang; Qingfeng Wang; Meng Wang; Xi Li; Chao Zhang
Journal:  Ther Clin Risk Manag       Date:  2021-04-22       Impact factor: 2.423

3.  What is the advantage of rectal amputation with an initial perineal approach for primary anorectal carcinoma?

Authors:  Kimihiko Funahashi; Mayu Goto; Tomoaki Kaneko; Mitsunori Ushigome; Satoru Kagami; Takamaru Koda; Yasuo Nagashima; Kimihiko Yoshida; Yasuyuki Miura
Journal:  BMC Surg       Date:  2020-02-03       Impact factor: 2.102

4.  Ki67 expression and localization of T cells after neoadjuvant therapies as reliable predictive markers in rectal cancer.

Authors:  Ken Imaizumi; Toshihiro Suzuki; Motohiro Kojima; Manami Shimomura; Naoki Sakuyama; Yuichiro Tsukada; Takeshi Sasaki; Yuji Nishizawa; Akinobu Taketomi; Masaaki Ito; Tetsuya Nakatsura
Journal:  Cancer Sci       Date:  2019-12-18       Impact factor: 6.716

  4 in total

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