Literature DB >> 29855030

Insulin hexamer dissociation dynamics revealed by photoinduced T-jumps and time-resolved X-ray solution scattering.

Dolev Rimmerman1, Denis Leshchev, Darren J Hsu, Jiyun Hong, Baxter Abraham, Irina Kosheleva, Robert Henning, Lin X Chen.   

Abstract

The structural dynamics of insulin hexamer dissociation were studied by the photoinduced temperature jump technique and monitored by time-resolved X-ray scattering. The process of hexamer dissociation was found to involve several transient intermediates, including an expanded hexamer and an unstable tetramer. Our findings provide insights into the mechanisms of protien-protein association.

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Year:  2018        PMID： 29855030      PMCID： PMC6041135          DOI： 10.1039/c8pp00034d

Source DB:  PubMed          Journal:  Photochem Photobiol Sci        ISSN： 1474-905X            Impact factor:   3.982


  46 in total

1.  Structural characterisation and functional significance of transient protein-protein interactions.

Authors:  Irene M A Nooren; Janet M Thornton
Journal:  J Mol Biol       Date:  2003-01-31       Impact factor: 5.469

2.  Unifying features in protein-folding mechanisms.

Authors:  Stefano Gianni; Nicholas R Guydosh; Faaizah Khan; Teresa D Caldas; Ugo Mayor; George W N White; Mari L DeMarco; Valerie Daggett; Alan R Fersht
Journal:  Proc Natl Acad Sci U S A       Date:  2003-10-31       Impact factor: 11.205

Review 3.  A practical guide to small angle X-ray scattering (SAXS) of flexible and intrinsically disordered proteins.

Authors:  Alexey G Kikhney; Dmitri I Svergun
Journal:  FEBS Lett       Date:  2015-08-29       Impact factor: 4.124

4.  Transient 2D IR spectroscopy of ubiquitin unfolding dynamics.

Authors:  Hoi Sung Chung; Ziad Ganim; Kevin C Jones; Andrei Tokmakoff
Journal:  Proc Natl Acad Sci U S A       Date:  2007-06-05       Impact factor: 11.205

5.  Multimerization and aggregation of native-state insulin: effect of zinc.

Authors:  Yisheng Xu; Yunfeng Yan; Daniel Seeman; Lianhong Sun; Paul L Dubin
Journal:  Langmuir       Date:  2011-12-05       Impact factor: 3.882

6.  Monitoring and inhibition of insulin fibrillation by a small organic fluorogen with aggregation-induced emission characteristics.

Authors:  Yuning Hong; Luming Meng; Sijie Chen; Chris Wai Tung Leung; Lin-Tai Da; Mahtab Faisal; Daniel-Adriano Silva; Jianzhao Liu; Jacky Wing Yip Lam; Xuhui Huang; Ben Zhong Tang
Journal:  J Am Chem Soc       Date:  2012-01-10       Impact factor: 15.419

7.  Impulsive solvent heating probed by picosecond x-ray diffraction.

Authors:  M Cammarata; M Lorenc; T K Kim; J H Lee; Q Y Kong; E Pontecorvo; M Lo Russo; G Schiró; A Cupane; M Wulff; H Ihee
Journal:  J Chem Phys       Date:  2006-03-28       Impact factor: 3.488

8.  Direct Observation of Insulin Association Dynamics with Time-Resolved X-ray Scattering.

Authors:  Dolev Rimmerman; Denis Leshchev; Darren J Hsu; Jiyun Hong; Irina Kosheleva; Lin X Chen
Journal:  J Phys Chem Lett       Date:  2017-09-05       Impact factor: 6.475

9.  Visualizing solution-phase reaction dynamics with time-resolved X-ray liquidography.

Authors:  Hyotcherl Ihee
Journal:  Acc Chem Res       Date:  2009-02-17       Impact factor: 22.384

10.  Sequential conformational transitions and α-helical supercoiling regulate a sensor histidine kinase.

Authors:  Oskar Berntsson; Ralph P Diensthuber; Matthijs R Panman; Alexander Björling; Emil Gustavsson; Maria Hoernke; Ashley J Hughes; Léocadie Henry; Stephan Niebling; Heikki Takala; Janne A Ihalainen; Gemma Newby; Silke Kerruth; Joachim Heberle; Marianne Liebi; Andreas Menzel; Robert Henning; Irina Kosheleva; Andreas Möglich; Sebastian Westenhoff
Journal:  Nat Commun       Date:  2017-08-18       Impact factor: 14.919
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  6 in total

1.  Revealing Fast Structural Dynamics in pH-Responsive Peptides with Time-Resolved X-ray Scattering.

Authors:  Dolev Rimmerman; Denis Leshchev; Darren J Hsu; Jiyun Hong; Baxter Abraham; Robert Henning; Irina Kosheleva; Lin X Chen
Journal:  J Phys Chem B       Date:  2019-02-27       Impact factor: 2.991

2.  Integrating solvation shell structure in experimentally driven molecular dynamics using x-ray solution scattering data.

Authors:  Darren J Hsu; Denis Leshchev; Irina Kosheleva; Kevin L Kohlstedt; Lin X Chen
Journal:  J Chem Phys       Date:  2020-05-29       Impact factor: 3.488

Review 3.  Time-resolved X-ray scattering studies of proteins.

Authors:  Hyun Sun Cho; Friedrich Schotte; Valentyn Stadnytskyi; Philip Anfinrud
Journal:  Curr Opin Struct Biol       Date:  2021-06-25       Impact factor: 7.786

4.  X-ray snapshots reveal conformational influence on active site ligation during metalloprotein folding.

Authors:  Darren J Hsu; Denis Leshchev; Dolev Rimmerman; Jiyun Hong; Matthew S Kelley; Irina Kosheleva; Xiaoyi Zhang; Lin X Chen
Journal:  Chem Sci       Date:  2019-09-03       Impact factor: 9.825

5.  Determining the charge distribution and the direction of bond cleavage with femtosecond anisotropic x-ray liquidography.

Authors:  Jun Heo; Jong Goo Kim; Eun Hyuk Choi; Hosung Ki; Doo-Sik Ahn; Jungmin Kim; Seonggon Lee; Hyotcherl Ihee
Journal:  Nat Commun       Date:  2022-01-26       Impact factor: 14.919

6.  Temperature-jump solution X-ray scattering reveals distinct motions in a dynamic enzyme.

Authors:  Michael C Thompson; Benjamin A Barad; Alexander M Wolff; Hyun Sun Cho; Friedrich Schotte; Daniel M C Schwarz; Philip Anfinrud; James S Fraser
Journal:  Nat Chem       Date:  2019-09-16       Impact factor: 24.427
  6 in total

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