Literature DB >> 2985187

Presynaptic localization of B-50 phosphoprotein: the (ACTH)-sensitive protein kinase substrate involved in rat brain polyphosphoinositide metabolism.

W H Gispen, J L Leunissen, A B Oestreicher, A J Verkleij, H Zwiers.   

Abstract

This study describes the ultrastructural localization in rat hippocampal tissue in situ and in isolated synaptosomes of the brain-specific phosphoprotein B-50, using affinity purified anti-B-50 immunoglobulins (IgGs). Evidence is presented for the presynaptic localization of B-50 in rat brain. Given this specific localization a model is presented outlining the presumed function of the B-50 protein in the membrane and describing possible neuromodulation by adrenocorticotropin hormone (ACTH)-like peptides.

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Year:  1985        PMID： 2985187     DOI： 10.1016/0006-8993(85)91054-6

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  18 in total

Review 1.  Regenerating neurons. Changes in protein phosphorylation.

Authors:  L Austin; J G Watterson; M T Hearn
Journal:  Mol Neurobiol       Date:  1992 Summer-Fall       Impact factor: 5.590

2.  Statistical analysis of long-term potentiation of large excitatory postsynaptic potentials recorded in guinea pig hippocampal slices: binomial model.

Authors:  U Kuhnt; G Hess; L L Voronin
Journal:  Exp Brain Res       Date:  1992       Impact factor: 1.972

Review 3.  Molecular analysis of the function of the neuronal growth-associated protein GAP-43 by genetic intervention.

Authors:  R L Neve; K J Ivins; L I Benowitz; M J During; A I Geller
Journal:  Mol Neurobiol       Date:  1991       Impact factor: 5.590

4.  Ca2+-dependent interaction of the growth-associated protein GAP-43 with the synaptic core complex.

Authors:  T Haruta; N Takami; M Ohmura; Y Misumi; Y Ikehara
Journal:  Biochem J       Date:  1997-07-15       Impact factor: 3.857

5.  Growth-associated protein GAP-43 is expressed selectively in associative regions of the adult human brain.

Authors:  R L Neve; E A Finch; E D Bird; L I Benowitz
Journal:  Proc Natl Acad Sci U S A       Date:  1988-05       Impact factor: 11.205

Review 6.  Role of the growth cone in neuronal differentiation.

Authors:  C O Van Hooff; A B Oestreicher; P N De Graan; W H Gispen
Journal:  Mol Neurobiol       Date:  1989 Spring-Summer       Impact factor: 5.590

7.  Phosphorylation of the neuronal protein kinase C substrate B-50: in vitro assay conditions alter sensitivity to ACTH.

Authors:  V J Aloyo; H Zwiers; P N De Graan; W H Gispen
Journal:  Neurochem Res       Date:  1988-04       Impact factor: 3.996

Review 8.  Role of the growth-associated protein B-50/GAP-43 in neuronal plasticity.

Authors:  W H Gispen; H B Nielander; P N De Graan; A B Oestreicher; L H Schrama; P Schotman
Journal:  Mol Neurobiol       Date:  1991       Impact factor: 5.590

9.  Production and characterization of antibodies against C-terminal peptide of protein F1: a novel phosphorylation at serine 209 of the peptide by protein kinase C.

Authors:  H M Azzazy; G W Gross; M C Wu
Journal:  Neurochem Res       Date:  1994-03       Impact factor: 3.996

10.  The behavioral syndrome induced by adreno corticotropic hormone in rats is prevented by Ca++ channel blockade.

Authors:  R Poggioli; E Rasori; A Bertolini
Journal:  J Endocrinol Invest       Date:  1993-02       Impact factor: 4.256
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