Literature DB >> 29851492

An Unexpected FeCl3-Catalyzed Cascade Reaction of Indoles and o-Hydroxychalcones for the Assembly of Chromane-Bridged Polycyclic Indoles.

Wenbo Wang1, Xuguan Bai1, Shaojing Jin1, Jiaomei Guo1, Yang Zhao1, Hongjie Miao1, Yanshuo Zhu1, Qilin Wang1, Zhanwei Bu1.   

Abstract

An unexpected FeCl3-catalyzed cascade reaction of simple indoles and o-hydroxychalcone was reported, leading to densely functionalized and strained chromane-bridged polycyclic indoles in moderate to good yields. This reaction not only establishes a new transformation of indoles and o-hydroxychalcones but also provides an efficient method for the synthesis of structurally complex and congested chromane-bridged polycyclic indoles.

Entities:  

Year:  2018        PMID： 29851492     DOI： 10.1021/acs.orglett.8b01107

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  2 in total

1.  Synthesis and Structural Characterization of 1-(E-1-Arylpropenon-3-yl)-3,4,6-tri-O-benzyl-d-glucals and Their Transformation into Pentasubstituted (2R,3S,4R)-Chromanes via Pd-Catalyzed Cross Dehydrogenative Coupling Reaction.

Authors:  Bhawani Shankar; Vinod Khatri; Banty Kumar; Vipin K Maikhuri; Amit Kumar; Rashmi Tomar; Ashok K Prasad
Journal:  ACS Omega       Date:  2021-04-22

2.  Skeletal remodeling of chalcone-based pyridinium salts to access isoindoline polycycles and their bridged derivatives.

Authors:  Lele Wang; Huabin Han; Lijie Gu; Wenjing Zhang; Junwei Zhao; Qilin Wang
Journal:  Chem Sci       Date:  2021-11-09       Impact factor: 9.825
  2 in total

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