Literature DB >> 29850891

Motif scraper: a cross-platform, open-source tool for identifying degenerate nucleotide motif matches in FASTA files.

Elisha D O Roberson1,2.   

Abstract

Summary: Many genomic features are defined not by exact sequence matches, but by degenerate nucleotide motifs that represent multiple compatible matches. While there are databases cataloging genomic features, such as the location of transcription factor motifs, for commonly used model species, identifying the locations of novel motifs, known motifs in non-model genomes, or known motifs in personal whole-genomes is difficult. I designed motif scraper to overcome this limitation, allowing for efficient, multiprocessor motif searches in any FASTA file. Availability and implementation: The motif scraper package (MIT license) is available via PyPI, and the Python source is available on GitHub at https://github.com/RobersonLab/motif_scraper.

Mesh:

Year:  2018        PMID: 29850891      PMCID: PMC6223366          DOI: 10.1093/bioinformatics/bty437

Source DB:  PubMed          Journal:  Bioinformatics        ISSN: 1367-4803            Impact factor:   6.937


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  2 in total

1.  Identification of upstream transcription factor binding sites in orthologous genes using mixed Student's t-test statistics.

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2.  A catalog of CasX genome editing sites in common model organisms.

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  2 in total

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