Literature DB >> 29848520

Myeloid sarcoma of the small intestine in a patient without overt acute myeloid leukaemia: a challenging diagnosis of a rare condition.

Rodrigo Athayde Nemésio1,2, Beatriz Costa1,2, Carlos Abrantes3,4, Júlio Soares Leite1,2.   

Abstract

Myeloid sarcoma (MS) is a rare condition that most commonly occurs in the setting of acute myeloidleukaemia (AML) or other chronic myeloproliferative disorders. It presents as an abnormal growth that can develop anywhere in the human body, and its clinical manifestations are often non-specific.We present the case of a patient admitted to the emergency room with bowel obstruction. After careful clinical assessment, she underwent a right hemicolectomy. After a thorough examination of the surgical pathology specimen, including testing a wide array of immunohistochemical markers, the patient was timely diagnosed with MS, allowing for the implementation of the appropriate treatment to achieve complete remission. This is crucial, since non-leukaemic patients with untreated MS always progress to AML, and have a better prognosis if adequate therapy is implemented early. Our patient is now in the second postoperative year and shows no signs of relapse. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Entities:  

Keywords:  gastrointestinal surgery; malignant and benign haematology; pathology; small intestine cancer; surgical oncology

Mesh:

Year:  2018        PMID: 29848520      PMCID: PMC5976126          DOI: 10.1136/bcr-2017-222718

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  14 in total

Review 1.  Comparison in treatments of nonleukemic granulocytic sarcoma: report of two cases and a review of 72 cases in the literature.

Authors:  Kunihiko Yamauchi; Masami Yasuda
Journal:  Cancer       Date:  2002-03-15       Impact factor: 6.860

2.  Small intestinal cancer: a population-based study of incidence and survival patterns in the United States, 1992 to 2006.

Authors:  Osama Qubaiah; Susan S Devesa; Charles E Platz; Mark M Huycke; Graça M Dores
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2010-07-20       Impact factor: 4.254

3.  Myeloid sarcoma: clinico-pathologic, phenotypic and cytogenetic analysis of 92 adult patients.

Authors:  S A Pileri; S Ascani; M C Cox; C Campidelli; F Bacci; M Piccioli; P P Piccaluga; C Agostinelli; S Asioli; D Novero; M Bisceglia; M Ponzoni; A Gentile; P Rinaldi; V Franco; D Vincelli; A Pileri; R Gasbarra; B Falini; P L Zinzani; M Baccarani
Journal:  Leukemia       Date:  2006-12-14       Impact factor: 11.528

Review 4.  Granulocytic sarcoma of the small intestine.

Authors:  Shane K Kohl; Patricia Aoun
Journal:  Arch Pathol Lab Med       Date:  2006-10       Impact factor: 5.534

5.  Myeloid sarcoma is associated with superior event-free survival and overall survival compared with acute myeloid leukemia.

Authors:  Apostolia-Maria Tsimberidou; Hagop M Kantarjian; Sijin Wen; Michael J Keating; Susan O'Brien; Mark Brandt; Sherry Pierce; Emil J Freireich; L Jeffrey Medeiros; Elihu Estey
Journal:  Cancer       Date:  2008-09-15       Impact factor: 6.860

6.  Acute myeloid leukemia presenting as "bowel upset": a case report.

Authors:  Smeeta Gajendra; Ajay Gogia; Prasenjit Das; Ritu Gupta; Pranay Tanwar
Journal:  J Clin Diagn Res       Date:  2014-07-20

7.  Isolated chloroma: the effect of early antileukemic therapy.

Authors:  K R Imrie; M J Kovacs; D Selby; J Lipton; B J Patterson; D Pantalony; P Poldre; B Y Ngan; A Keating
Journal:  Ann Intern Med       Date:  1995-09-01       Impact factor: 25.391

8.  Myeloid sarcomas: a histologic, immunohistochemical, and cytogenetic study.

Authors:  Borislav A Alexiev; Wenle Wang; Yi Ning; Saranya Chumsri; Ivana Gojo; William H Rodgers; Sanford A Stass; Xianfeng F Zhao
Journal:  Diagn Pathol       Date:  2007-10-31       Impact factor: 2.644

9.  Small-bowel myeloid sarcoma: Report of a case with atypical presentation.

Authors:  Carlo M Girelli; Valentina Carsenzuola; Marilù Latargia; Alessandra Aguzzi; Giovanni Serio
Journal:  Int J Surg Case Rep       Date:  2014-07-10

10.  Gastric Burkitt lymphoma: A case report and literature review.

Authors:  Simona Gurzu; Tivadar Bara; Tivadar Jr Bara; Mihai Turcu; Ciprian Valentin Mardare; Ioan Jung
Journal:  Medicine (Baltimore)       Date:  2017-12       Impact factor: 1.817

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