Literature DB >> 2984770

Construction and recovery of viable retroviral genomes carrying a bacterial suppressor transfer RNA gene.

L I Lobel, M Patel, W King, M C Nguyen-Huu, S P Goff.   

Abstract

The integration of retroviral genomes into cellular DNA can induce mutations by altering the expression of nearby cellular genes and can serve to identify the gene affected. The construction of a retrovirus that stably carries a suppressor transfer RNA gene from Escherichia coli has allowed facile recovery of the viral genome in vectors marked with amber mutations. This virus can be used for rapid isolation of cellular sequences at the site of proviral insertion.

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Year:  1985        PMID： 2984770     DOI： 10.1126/science.2984770

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  19 in total

1.  Genomic stability of murine leukemia viruses containing insertions at the Env-3' untranslated region boundary.

Authors:  C R Logg; A Logg; C K Tai; P M Cannon; N Kasahara
Journal:  J Virol       Date:  2001-08       Impact factor: 5.103

2.  Efficient replication, integration, and packaging of retroviral vectors with modified long terminal repeats containing the packaging signal.

Authors:  S Joshi; A Van Brunschot; I Robson; A Bernstein
Journal:  Nucleic Acids Res       Date:  1990-07-25       Impact factor: 16.971

3.  Retroviral integration: structure of the initial covalent product and its precursor, and a role for the viral IN protein.

Authors:  P O Brown; B Bowerman; H E Varmus; J M Bishop
Journal:  Proc Natl Acad Sci U S A       Date:  1989-04       Impact factor: 11.205

4.  Charons 36 to 40: multi enzyme, high capacity, recombination deficient replacement vectors with polylinkers and polystuffers.

Authors:  I S Dunn; F R Blattner
Journal:  Nucleic Acids Res       Date:  1987-03-25       Impact factor: 16.971

5.  Retroviral replicating vectors in cancer.

Authors:  Christopher R Logg; Joan M Robbins; Douglas J Jolly; Harry E Gruber; Noriyuki Kasahara
Journal:  Methods Enzymol       Date:  2012       Impact factor: 1.600

6.  An MuLV transmission vector system designed to permit recovery in E. coli of proviral and cellular flanking sequences.

Authors:  P Jørgensen; T Mikkelsen; F S Pedersen; N O Kjeldgaard
Journal:  Virus Genes       Date:  1988-03       Impact factor: 2.332

7.  Formation of an inverted duplication can be an initial step in gene amplification.

Authors:  J C Ruiz; G M Wahl
Journal:  Mol Cell Biol       Date:  1988-10       Impact factor: 4.272

8.  Effects of 3' untranslated region mutations on plus-strand priming during moloney murine leukemia virus replication.

Authors:  N D Robson; A Telesnitsky
Journal:  J Virol       Date:  1999-02       Impact factor: 5.103

9.  Inserting a nuclear targeting signal into a replication-competent Moloney murine leukemia virus affects viral export and is not sufficient for cell cycle-independent infection.

Authors:  Jennifer A Seamon; Kathryn S Jones; Christina Miller; Monica J Roth
Journal:  J Virol       Date:  2002-08       Impact factor: 5.103

10.  Fv-1 restriction and its effects on murine leukemia virus integration in vivo and in vitro.

Authors:  P M Pryciak; H E Varmus
Journal:  J Virol       Date:  1992-10       Impact factor: 5.103
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