Literature DB >> 2983003

Lack of quantitative correlation between the neutralization of poliovirus and the antibody-mediated pI shift of the virions.

P Brioen, A A Thomas, A Boeyé.   

Abstract

The effect of mono- and polyclonal antibodies on the infectivity and pI (isoelectric pH) of type 1 poliovirus was studied. According to Mandel's hypothesis, the isoelectric pH of poliovirus should change to about pI 4 upon neutralization. However, several antibodies did not follow this rule. Moreover, when antibodies did shift the pI, no quantitative correlation existed between the extent of neutralization and the amount of poliovirus shifted to low pI.

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Year:  1985        PMID： 2983003     DOI： 10.1099/0022-1317-66-3-609

Source DB:  PubMed          Journal:  J Gen Virol        ISSN： 0022-1317            Impact factor:   3.891


  8 in total

1.  Structure of a neutralizing antibody bound monovalently to human rhinovirus 2.

Authors:  E A Hewat; T C Marlovits; D Blaas
Journal:  J Virol       Date:  1998-05       Impact factor: 5.103

2.  Relationship between poliovirus neutralization and aggregation.

Authors:  A A Thomas; R Vrijsen; A Boeyé
Journal:  J Virol       Date:  1986-08       Impact factor: 5.103

3.  Neutralization of poliovirus by polyclonal antibodies requires binding of a single IgG molecule per virion.

Authors:  K Wetz; P Willingmann; H Zeichhardt; K O Habermehl
Journal:  Arch Virol       Date:  1986       Impact factor: 2.574

4.  Evidence for a complex structure of neutralization antigenic site I of poliovirus type 1 Mahoney.

Authors:  K Wiegers; H Uhlig; R Dernick
Journal:  J Virol       Date:  1988-05       Impact factor: 5.103

5.  Antibody-mediated neutralization of human rhinovirus 14 explored by means of cryoelectron microscopy and X-ray crystallography of virus-Fab complexes.

Authors:  Z Che; N H Olson; D Leippe; W M Lee; A G Mosser; R R Rueckert; T S Baker; T J Smith
Journal:  J Virol       Date:  1998-06       Impact factor: 5.103

6.  Structure of human rhinovirus complexed with Fab fragments from a neutralizing antibody.

Authors:  T J Smith; N H Olson; R H Cheng; H Liu; E S Chase; W M Lee; D M Leippe; A G Mosser; R R Rueckert; T S Baker
Journal:  J Virol       Date:  1993-03       Impact factor: 5.103

Review 7.  The antiviral activity of antibodies in vitro and in vivo.

Authors:  P W Parren; D R Burton
Journal:  Adv Immunol       Date:  2001       Impact factor: 3.543

8.  Extracellular Hepatitis B Virus RNAs Are Heterogeneous in Length and Circulate as Capsid-Antibody Complexes in Addition to Virions in Chronic Hepatitis B Patients.

Authors:  Lu Bai; Xiaonan Zhang; Maya Kozlowski; Weixia Li; Min Wu; Jiangxia Liu; Liang Chen; Jiming Zhang; Yuxian Huang; Zhenghong Yuan
Journal:  J Virol       Date:  2018-11-27       Impact factor: 5.103
  8 in total

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