Literature DB >> 2981593

IgG-antibodies to HTLV-III in patients with AIDS, LAS, and persons at risk of AIDS in West Germany.

R Hehlmann, G Kreeb, V Erfle, H Piechowiak, G Krüger, F D Goebel.   

Abstract

In a first seroepidemiological study on the prevalence of the human T-lymphotropic retrovirus HTLV-III in West Germany, sera of 26 patients with acquired immunodeficiency syndrome (AIDS), 33 patients with lymphadenopathy syndrome (LAS) or AIDS related complex (ARC), and 113 homosexual men at risk of AIDS were screened for IgG antibodies to HTLV-III by an enzyme linked immunosorbent assay (ELISA). 22 out of 26 AIDS-patients (84.6%), 24 out of 33 LAS-patients (72.7%), and 44 out of 113 healthy homosexual men with increased risk of AIDS (38.9%) were found positive for antibodies to HTLV-III. Heterosexual controls including healthy laboratory workers and medical personnel with contact to AIDS patients did not show antibodies to HTLV-III. The HTLV-III antibodies analyzed predominantly recognize a protein of molecular weight 41,000 (p41).

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Year:  1985        PMID： 2981593     DOI： 10.1007/bf00319764

Source DB:  PubMed          Journal:  Blut        ISSN： 0006-5242


  18 in total

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Journal:  Proc Natl Acad Sci U S A       Date:  1979-09       Impact factor: 11.205

2.  Antibodies to HTLV-III in patients with acquired immunodeficiency or lymphadenopathy syndrome in West Germany.

Authors:  R Hehlmann; G Kreeb; V Erfle; H Piechowiak; G Krüger; F D Goebel
Journal:  Lancet       Date:  1984-11-10       Impact factor: 79.321

3.  Detection and quantification of type C viral proteins in tissues and sera with an enzyme immunoassay.

Authors:  H Schetters; R Hehlmann; V Erfle; M Ramanarayanan
Journal:  Infect Immun       Date:  1980-09       Impact factor: 3.441

4.  [Acquired immunodeficiency syndrome (AIDS). Case reports and diagnosis].

Authors:  O Braun-Falco; J Ring; P Rieber; G Riethmüller
Journal:  MMW Munch Med Wochenschr       Date:  1983-12-02

5.  Seroepidemiological studies of human T-lymphotropic retrovirus type III in acquired immunodeficiency syndrome.

Authors:  B Safai; M G Sarngadharan; J E Groopman; K Arnett; M Popovic; A Sliski; J Schüpbach; R C Gallo
Journal:  Lancet       Date:  1984-06-30       Impact factor: 79.321

6.  Isolation of new lymphotropic retrovirus from two siblings with haemophilia B, one with AIDS.

Authors:  E Vilmer; F Barre-Sinoussi; C Rouzioux; C Gazengel; F V Brun; C Dauguet; A Fischer; P Manigne; J C Chermann; C Griscelli
Journal:  Lancet       Date:  1984-04-07       Impact factor: 79.321

7.  Methods in laboratory investigation. Application of the indirect enzyme-linked immunosorbent assay microtest to the detection and surveillance of human t cell leukemia-lymphoma virus.

Authors:  C Saxinger; R C Gallo
Journal:  Lab Invest       Date:  1983-09       Impact factor: 5.662

8.  Antibodies to the core protein of lymphadenopathy-associated virus (LAV) in patients with AIDS.

Authors:  V S Kalyanaraman; C D Cabradilla; J P Getchell; R Narayanan; E H Braff; J C Chermann; F Barré-Sinoussi; L Montagnier; T J Spira; J Kaplan
Journal:  Science       Date:  1984-07-20       Impact factor: 47.728

9.  Frequent detection and isolation of cytopathic retroviruses (HTLV-III) from patients with AIDS and at risk for AIDS.

Authors:  R C Gallo; S Z Salahuddin; M Popovic; G M Shearer; M Kaplan; B F Haynes; T J Palker; R Redfield; J Oleske; B Safai
Journal:  Science       Date:  1984-05-04       Impact factor: 47.728

10.  Serological analysis of a subgroup of human T-lymphotropic retroviruses (HTLV-III) associated with AIDS.

Authors:  J Schüpbach; M Popovic; R V Gilden; M A Gonda; M G Sarngadharan; R C Gallo
Journal:  Science       Date:  1984-05-04       Impact factor: 47.728
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  5 in total

1.  Seroepidemiology of HTLV-III (LAV) in the Federal Republic of Germany.

Authors:  G Hunsmann; J Schneider; H Bayer; R Kurth; A Werner; H D Brede; V Erfle; W Mellert; H R Brodt; L Bergmann
Journal:  Klin Wochenschr       Date:  1985-03-01

2.  [AIDS and HTLV-III in West Germany: the status February 1985].

Authors:  R Hehlmann; V Erfle; G Hunsmann; R Kurth
Journal:  Klin Wochenschr       Date:  1985-05-02

3.  HTLV III antibodies and immunological alterations in hemophilia patients.

Authors:  E Seifried; G Pindur; H Stötter; F Porzsolt; H Rasche; V Erfle; R Hehlmann; H Heimpel
Journal:  Klin Wochenschr       Date:  1986-02-03

4.  Prevalence of antibodies to human T-lymphotropic virus-III (HTLV-III) in hemophiliacs and other patients chronically substituted with blood products.

Authors:  V Erfle; R Hehlmann; W Mellert; F D Goebel; H Rasokat; E Lechler; P Hellstern; M Köhler; E Seifried; H Heimpel
Journal:  Blut       Date:  1985-10

5.  Changing biclonal gammopathy due to different lymphocyte clones in acquired immunodeficiency syndrome with Kaposi's sarcoma.

Authors:  H Piechowiak; R Hehlmann; J Abb; V Erfle; F D Goebel; M M Kochen; G Kreeb
Journal:  Klin Wochenschr       Date:  1985-10-15
  5 in total

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