Literature DB >> 29805246

A Genomically Informed Education System? Challenges for Behavioral Genetics.

Maya Sabatello1.   

Abstract

The exponential growth of genetic knowledge and precision medicine research raises hopes for improved prevention, diagnosis, and treatment options for children with behavioral and psychiatric conditions. Although well-intended, this prospect also raise the possibility-and concern-that behavioral, including psychiatric genetic data would be increasingly used-or misused-outside the clinical context, such as educational settings. Indeed, there are ongoing calls to endorse a "personalized education" model that would tailor educational interventions to children's behavioral and psychiatric genetic makeup. This article explores the justifications for, and prospects and pitfalls of such endeavors. It considers the scientific challenges and highlights the ethical, legal, and social issues that will likely arise should behavioral genetic data become available (or be perceived as such) and are routinely incorporated in student education records. These include: when to disclose students' behavioral and psychiatric genetic profile; whose genomic privacy is protected and by whom; and how students' genetic data may affect education-related decisions. I argue that the introduction of behavioral genetics in schools may overshadow the need to address underlying structural and environmental factors that increase the risk for psychiatric conditions of all students, and that the unregulated use of student behavioral genetic profiles may lead to unintended consequences that are detrimental for individuals, families and communities. Relevant stakeholders-from parents and students to health professionals, educators, and policy-makers-ought to consider these issues before we forge ahead with a genomically informed education system.

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Year:  2018        PMID: 29805246      PMCID: PMC5967657          DOI: 10.1177/1073110518766027

Source DB:  PubMed          Journal:  J Law Med Ethics        ISSN: 1073-1105            Impact factor:   1.718


  89 in total

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2.  Public Health in the Precision-Medicine Era.

Authors:  Ronald Bayer; Sandro Galea
Journal:  N Engl J Med       Date:  2015-08-06       Impact factor: 91.245

3.  No evidence for interaction between MAOA and childhood adversity for antisocial behavior.

Authors:  Zoë Prichard; Andrew Mackinnon; Anthony F Jorm; Simon Easteal
Journal:  Am J Med Genet B Neuropsychiatr Genet       Date:  2008-03-05       Impact factor: 3.568

4.  Currents in contemporary ethics. GINA, the ADA, and genetic discrimination in employment.

Authors:  Mark A Rothstein
Journal:  J Law Med Ethics       Date:  2008       Impact factor: 1.718

5.  Raising Genomic Citizens: Adolescents and the Return of Secondary Genomic Findings.

Authors:  Maya Sabatello; Paul S Appelbaum
Journal:  J Law Med Ethics       Date:  2016-06       Impact factor: 1.718

6.  Psychiatric genetics: a survey of psychiatrists' knowledge, opinions, and practice patterns.

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7.  Community attitudes to genetic susceptibility-based mental health interventions for healthy people in a large national sample.

Authors:  Alex Wilde; Bettina Meiser; Philip B Mitchell; Peter R Schofield
Journal:  J Affect Disord       Date:  2011-07-16       Impact factor: 4.839

8.  Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene.

Authors:  Avshalom Caspi; Karen Sugden; Terrie E Moffitt; Alan Taylor; Ian W Craig; HonaLee Harrington; Joseph McClay; Jonathan Mill; Judy Martin; Antony Braithwaite; Richie Poulton
Journal:  Science       Date:  2003-07-18       Impact factor: 47.728

Review 9.  Epigenetic approaches to psychiatric disorders.

Authors:  Carolyn Ptak; Arturas Petronis
Journal:  Dialogues Clin Neurosci       Date:  2010       Impact factor: 5.986

10.  Spitting for Science: Danish High School Students Commit to a Large-Scale Self-Reported Genetic Study.

Authors:  Georgios Athanasiadis; Frank G Jørgensen; Jade Y Cheng; Peter C Kjærgaard; Mikkel H Schierup; Thomas Mailund
Journal:  PLoS One       Date:  2016-08-29       Impact factor: 3.240

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  6 in total

Review 1.  International Society of Psychiatric Genetics Ethics Committee: Issues facing us.

Authors:  Gabriel Lázaro-Muñoz; Maya Sabatello; Laura Huckins; Holly Peay; Franziska Degenhardt; Bettina Meiser; Todd Lencz; Takahiro Soda; Anna Docherty; David Crepaz-Keay; Jehannine Austin; Roseann E Peterson; Lea K Davis
Journal:  Am J Med Genet B Neuropsychiatr Genet       Date:  2019-05-23       Impact factor: 3.568

2.  Genomic Essentialism: Its Provenance and Trajectory as an Anticipatory Ethical Concern.

Authors:  Maya Sabatello; Eric Juengst
Journal:  Hastings Cent Rep       Date:  2019-05       Impact factor: 2.683

3.  Nature vs. Nurture in Precision Education: Insights of Parents and the Public.

Authors:  Maya Sabatello; Bree Martin; Thomas Corbeil; Seonjoo Lee; Bruce G Link; Paul S Appelbaum
Journal:  AJOB Empir Bioeth       Date:  2021-10-13

4.  The double helix at school: Behavioral genetics, disability, and precision education.

Authors:  Maya Sabatello; Beverly J Insel; Thomas Corbeil; Bruce G Link; Paul S Appelbaum
Journal:  Soc Sci Med       Date:  2021-04-20       Impact factor: 5.379

5.  Can education be personalised using pupils' genetic data?

Authors:  Tim T Morris; Neil M Davies; George Davey Smith
Journal:  Elife       Date:  2020-03-10       Impact factor: 8.713

Review 6.  Ethical, anticipatory genomics research on human behavior means celebrating disagreement.

Authors:  Daphne Oluwaseun Martschenko; Sam Trejo
Journal:  HGG Adv       Date:  2021-12-21
  6 in total

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