Literature DB >> 29803797

New developments in patients with eosinophilic gastrointestinal diseases presented at the CEGIR/TIGERS Symposium at the 2018 American Academy of Allergy, Asthma & Immunology Meeting.

Jonathan M Spergel1, Seema S Aceves2, Kara Kliewer3, Nirmala Gonsalves4, Mirna Chehade5, Joshua B Wechsler6, Marion Groetch5, Joshua Friedlander7, Evan S Dellon8, Wendy Book9, Ikuo Hirano4, Amanda B Muir10, Antonella Cianferoni1, Lisa Spencer11, Chris A Liacouras10, Edaire Cheng12, Leah Kottyan13, Ting Wen3, Thomas Platts-Mills14, Marc E Rothenberg15.   

Abstract

The Consortium of Eosinophilic Gastrointestinal Diseases and the International Gastrointestinal Eosinophil Researchers organized a day-long symposium at the recent 2018 Annual Meeting of the American Academy of Allergy, Asthma & Immunology, which was coupled for the first time with the World Allergy Organization meeting to create an international platform. The symposium featured experts in many facets of eosinophilic gastrointestinal diseases, including allergy, immunology, gastroenterology, pathology, and nutrition, and was a well-attended event. The basic science, genetics, cellular immunology, and clinical features of the diseases, with a focus on epithelial, eosinophil, and mast cell responses, as well as current and emerging treatment options, were reviewed. Here we briefly review some of the highlights of the material presented at the meeting.
Copyright © 2018. Published by Elsevier Inc.

Entities:  

Keywords:  Eosinophilic esophagitis; diagnosis; food allergy; treatment

Mesh:

Year:  2018        PMID: 29803797      PMCID: PMC6129859          DOI: 10.1016/j.jaci.2018.05.005

Source DB:  PubMed          Journal:  J Allergy Clin Immunol        ISSN: 0091-6749            Impact factor:   10.793


  52 in total

1.  Fluticasone and food allergen elimination reverse sub-epithelial fibrosis in children with eosinophilic esophagitis.

Authors:  Samer M A Abu-Sultaneh; Paul Durst; Virginia Maynard; Yoram Elitsur
Journal:  Dig Dis Sci       Date:  2010-05-11       Impact factor: 3.199

2.  Eosinophilic oesophagitis endotype classification by molecular, clinical, and histopathological analyses: a cross-sectional study.

Authors:  Tetsuo Shoda; Ting Wen; Seema S Aceves; J Pablo Abonia; Dan Atkins; Peter A Bonis; Julie M Caldwell; Kelley E Capocelli; Christina L Carpenter; Margaret H Collins; Evan S Dellon; Michael D Eby; Nirmala Gonsalves; Sandeep K Gupta; Gary W Falk; Ikuo Hirano; Paul Menard-Katcher; Jonathan T Kuhl; Jeffrey P Krischer; John Leung; Vincent A Mukkada; Jonathan M Spergel; Michael P Trimarchi; Guang-Yu Yang; Nives Zimmermann; Glenn T Furuta; Marc E Rothenberg
Journal:  Lancet Gastroenterol Hepatol       Date:  2018-05-03

3.  Invariant natural killer T cells in children with eosinophilic esophagitis.

Authors:  S Jyonouchi; C L Smith; F Saretta; V Abraham; K R Ruymann; P Modayur-Chandramouleeswaran; M-L Wang; J M Spergel; A Cianferoni
Journal:  Clin Exp Allergy       Date:  2014-01       Impact factor: 5.018

4.  Critical role for adaptive T cell immunity in experimental eosinophilic esophagitis in mice.

Authors:  Anil Mishra; James Schlotman; Meiqin Wang; Marc E Rothenberg
Journal:  J Leukoc Biol       Date:  2006-12-28       Impact factor: 4.962

5.  Lack of Knowledge and Low Readiness for Health Care Transition in Eosinophilic Esophagitis and Eosinophilic Gastroenteritis.

Authors:  Swathi Eluri; Wendy M Book; Ellyn Kodroff; Mary Jo Strobel; Jessica H Gebhart; Patricia D Jones; Paul Menard-Katcher; Maria E Ferris; Evan S Dellon
Journal:  J Pediatr Gastroenterol Nutr       Date:  2017-07       Impact factor: 2.839

6.  Eosinophilic esophagitis and symptoms possibly related to eosinophilic esophagitis in oral immunotherapy.

Authors:  Daniel Petroni; Jonathan M Spergel
Journal:  Ann Allergy Asthma Immunol       Date:  2018-02-01       Impact factor: 6.347

7.  Long-term assessment of esophageal remodeling in patients with pediatric eosinophilic esophagitis treated with topical corticosteroids.

Authors:  Jessica Rajan; Robert O Newbury; Arjun Anilkumar; Ranjan Dohil; David H Broide; Seema S Aceves
Journal:  J Allergy Clin Immunol       Date:  2015-07-30       Impact factor: 10.793

Review 8.  Thoughts on the complex relationship between gastroesophageal reflux disease and eosinophilic esophagitis.

Authors:  Stuart Jon Spechler; Robert M Genta; Rhonda F Souza
Journal:  Am J Gastroenterol       Date:  2007-06       Impact factor: 10.864

9.  Assessing Adherence and Barriers to Long-Term Elimination Diet Therapy in Adults with Eosinophilic Esophagitis.

Authors:  Ryan Wang; Ikuo Hirano; Bethany Doerfler; Angelika Zalewski; Nirmala Gonsalves; Tiffany Taft
Journal:  Dig Dis Sci       Date:  2018-04-02       Impact factor: 3.199

10.  Creating a multi-center rare disease consortium - the Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR).

Authors:  Katherine Cheng; Sandeep K Gupta; Susanna Kantor; Jonathan T Kuhl; Seema S Aceves; Peter A Bonis; Kelley E Capocelli; Christina Carpenter; Mirna Chehade; Margaret H Collins; Evan S Dellon; Gary W Falk; Rashmi Gopal-Srivastava; Nirmala Gonsalves; Ikuo Hirano; Eileen C King; John Leung; Jeffrey P Krischer; Vincent A Mukkada; Alain Schoepfer; Jonathan M Spergel; Alex Straumann; Guang-Yu Yang; Glenn T Furuta; Marc E Rothenberg
Journal:  Transl Sci Rare Dis       Date:  2017-12-18
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  4 in total

1.  Siglec-8 antibody reduces eosinophils and mast cells in a transgenic mouse model of eosinophilic gastroenteritis.

Authors:  Bradford A Youngblood; Emily C Brock; John Leung; Rustom Falahati; Bruce S Bochner; Henrik S Rasmussen; Kathryn Peterson; Christopher Bebbington; Nenad Tomasevic
Journal:  JCI Insight       Date:  2019-10-03

Review 2.  Advancing patient care through the Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR).

Authors:  Seema Aceves; Margaret H Collins; Marc E Rothenberg; Glenn T Furuta; Nirmala Gonsalves
Journal:  J Allergy Clin Immunol       Date:  2019-11-20       Impact factor: 10.793

Review 3.  Pathophysiology of eosinophilic esophagitis: recent advances and their clinical implications.

Authors:  Melanie A Ruffner; Katie Kennedy; Antonella Cianferoni
Journal:  Expert Rev Clin Immunol       Date:  2018-11-19       Impact factor: 5.124

4.  Evaluation of gene expression change in eosinophilic gastroenteritis.

Authors:  Mohammad-Mahdi Zadeh-Esmaeel; Mostafa Rezaei-Tavirani; Nayeb Ali Ahmadi; Reza Vafae
Journal:  Gastroenterol Hepatol Bed Bench       Date:  2019
  4 in total

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