Müesser Ahu Durhan1, Nursen Topcuoglu2, Guven Kulekci2, Ege Ozgentas3, Ilknur Tanboga1. 1. 1 Department of Paediatric Dentistry, Faculty of Dentistry, Marmara University, Istanbul, Turkey. 2. 2 Department of Microbiology, Faculty of Dentistry, Istanbul University, Istanbul, Turkey. 3. 3 Private Practice, Istanbul, Turkey.
Abstract
OBJECTIVE: The aim of this study was to examine the microbiological changes in newborn babies with cleft lip palate from birth up to age 3 and to correlate them with their caries levels and mothers' microbiological data and to compare with normal infants. BASIC RESEARCH DESIGN: Prospective. SETTINGS: Marmara University, Faculty of Dentistry, Pediatric Dentistry Clinic, and Şişli Hamidiye Etfal Education and Research Hospital New Born Clinic. PATIENTS/PARTICIPANTS: Cleft lip palate (n = 21) and healthy (n = 13) newborns and their mothers. MATERIAL AND METHODS: Intraoral samples were taken from babies in each group at least 3 times over the 3 years. Saliva samples of the mothers were collected just after the birth of the babies and examined microbiologically. Dental caries was noted as either present or absent. RESULTS: The most frequent microorganisms were candida, found at birth (n = 9, 42%) in cleft palate with or without cleft lip (CP±L) group. The number of babies infected with Lactobacilli were found to be significantly higher in the CP±L group than in the control group at birth ( P = .029) and after eruption of the first primary tooth ( P = .030). Mutans Streptococci were found in 10% of babies with CP±L at birth. Initial caries was identified in 20% of the babies with an oral cleft compared with 0% of the controls after eruption of the first primary incisors. CONCLUSION: The results show that the CP±L babies must be considered as a group with an increased caries risk.
OBJECTIVE: The aim of this study was to examine the microbiological changes in newborn babies with cleft lip palate from birth up to age 3 and to correlate them with their caries levels and mothers' microbiological data and to compare with normal infants. BASIC RESEARCH DESIGN: Prospective. SETTINGS: Marmara University, Faculty of Dentistry, Pediatric Dentistry Clinic, and Şişli Hamidiye Etfal Education and Research Hospital New Born Clinic. PATIENTS/PARTICIPANTS: Cleft lip palate (n = 21) and healthy (n = 13) newborns and their mothers. MATERIAL AND METHODS: Intraoral samples were taken from babies in each group at least 3 times over the 3 years. Saliva samples of the mothers were collected just after the birth of the babies and examined microbiologically. Dental caries was noted as either present or absent. RESULTS: The most frequent microorganisms were candida, found at birth (n = 9, 42%) in cleft palate with or without cleft lip (CP±L) group. The number of babies infected with Lactobacilli were found to be significantly higher in the CP±L group than in the control group at birth ( P = .029) and after eruption of the first primary tooth ( P = .030). Mutans Streptococci were found in 10% of babies with CP±L at birth. Initial caries was identified in 20% of the babies with an oral cleft compared with 0% of the controls after eruption of the first primary incisors. CONCLUSION: The results show that the CP±L babies must be considered as a group with an increased caries risk.
Authors: Y Zeng; M Youssef; L Wang; N Alkhars; M Thomas; R Cacciato; S Qing; O Ly-Mapes; J Xiao Journal: J Clin Pediatr Dent Date: 2020 Impact factor: 1.065
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Authors: S Abirami; Noopur Tushar Panchanadikar; M S Muthu; Kavitha Swaminathan; K C Vignesh; Amit Agarwal; Richard Kirubakaran Journal: Int J Clin Pediatr Dent Date: 2022