Literature DB >> 29797654

Transplantation of pediatric renal allografts from donors less than 10 kg.

Nicholas Mitrou1, Shahid Aquil1,2,3, Marie Dion1,2, Vivian McAlister1,2,3, Alp Sener1,2,3, Patrick P Luke1,2,3.   

Abstract

Few transplant programs use kidneys from donors with body weight (BW) < 10 kg. We hypothesized that pediatric en bloc transplants from donors with BW < 10 kg would provide similar transplant outcomes to larger grafts. All pediatric en bloc renal transplants performed at our center between 2001 and 2017 were reviewed (N = 28). Data were stratified by smaller (donor BW < 10 kg; n = 11) or larger donors (BW > 10 kg; n = 17). Renal volume was assessed during follow-up with ultrasound. Demographic characteristics were similar between the 2 groups of recipients. After mean follow-up of 44 months (smaller donors) and 124 months (larger donors), graft and patient outcomes were similar between groups. Serum creatinine at 1, 3, and 5 years was no different between groups. At 1 day posttransplant, mean total renal volume in the smaller donors was 28 ± 9 mm3 vs 45 ± 12 mm3 (P < .01). By 3 weeks, it was 53 ± 19 mm3 (smaller donors) versus 73 ± 19 mm3 (larger donors) (P = NS). Complication rates were similar between both groups with 1 case of venous thrombosis in the smaller group. With experience, outcomes are equivalent to those from larger pediatric donors.
© 2018 The American Society of Transplantation and the American Society of Transplant Surgeons.

Entities:  

Keywords:  clinical research/practice; deceased; donors and donation; kidney transplantation/nephrology; organ acceptance; organ procurement and allocation; surgical technique; urology

Year:  2018        PMID: 29797654     DOI: 10.1111/ajt.14946

Source DB:  PubMed          Journal:  Am J Transplant        ISSN: 1600-6135            Impact factor:   8.086


  7 in total

1.  The history of renal transplantation in Canada: A urologic perspective.

Authors:  Max Alexander Levine; Joseph L Chin; Andrew Rasmussen; Alp Sener; Patrick P Luke
Journal:  Can Urol Assoc J       Date:  2020-12       Impact factor: 1.862

2.  Transplantation of a single kidney from pediatric donors less than 10 kg to children with poor access to transplantation: a two-year outcome analysis.

Authors:  Xiaojun Su; Wenjun Shang; Longshan Liu; Jun Li; Qian Fu; Yonghua Feng; Huanxi Zhang; Ronghai Deng; Chenglin Wu; Zhigang Wang; Xinlu Pang; Björn Nashan; Guiwen Feng; Changxi Wang
Journal:  BMC Nephrol       Date:  2020-07-02       Impact factor: 2.388

3.  Kidney transplantation from small pediatric donors may be feasible to those who developed chronic refractory dialysis hypotension: a single-center experience.

Authors:  Lu Zheng; Hanying Jia; Rending Wang; Wenhan Peng; Junhao Lv; Wenhua Lei; Guangjun Liu; Yu Cui; Jianghua Chen; Jianyong Wu
Journal:  Ann Transl Med       Date:  2020-06

Review 4.  Utilisation of small paediatric donor kidneys for transplantation.

Authors:  Samir Damji; Chris J Callaghan; Ioannis Loukopoulos; Nicos Kessaris; Jelena Stojanovic; Stephen D Marks; Nizam Mamode
Journal:  Pediatr Nephrol       Date:  2018-09-20       Impact factor: 3.714

5.  Comparison of Outcomes of Kidney Transplantation From Extremely Low Body Weight ≤5kg Versus Larger Body Weight Pediatric Donors.

Authors:  Jiawei Peng; Helong Dai; Hedong Zhang; Shaojie Yu; Xubiao Xie; Fenghua Peng; Gongbin Lan; Shanbiao Hu; Yu Wang; Xiaotian Tang; Yong Guo; Chen Gao; Chunhua Fang; Manhua Nie; Xiaoqiong Yuan; Mingda Zhong; Zhouqi Tang; Tengfang Li; Siyu Sun; Hengchang Yao; Jianfei Hou; Ruixue Huang; Longkai Peng
Journal:  Front Immunol       Date:  2021-08-31       Impact factor: 7.561

6.  Donor-Recipient BSA Matching Is Prognostically Significant in Solitary and En Bloc Kidney Transplantation From Pediatric Circulatory Death Donors.

Authors:  Christopher J Little; Andre A S Dick; James D Perkins; Jorge D Reyes
Journal:  Transplant Direct       Date:  2021-07-19

7.  Successful single kidney transplantation from pediatric donors less than or equal to 10 kg to adult recipient: a retrospective cohort study.

Authors:  Chuxiao Chen; Xiaojun Su; Chenglin Wu; Longshan Liu; Huanxi Zhang; Ronghai Deng; Qian Fu; Xiaopeng Yuan; Yitao Zheng; Jiang Qiu; Guodong Chen; Gang Huang; Suxiong Deng; Jiguang Fei; Lizhong Chen; Jun Li; Changxi Wang
Journal:  Transl Pediatr       Date:  2021-06
  7 in total

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