Literature DB >> 29785449

Parkinson's disease increases the risk of perioperative complications after total knee arthroplasty: a nationwide database study.

Jared M Newman1, Nipun Sodhi2, Alyeesha B Wilhelm3, Anton Khlopas2, Alison K Klika2, Qais Naziri1, Thomas J Kryzak2, Carlos A Higuera2, Michael A Mont4.   

Abstract

PURPOSE: Therefore, the purpose of this study was to evaluate the short-term perioperative outcomes of PD patients who underwent total knee arthroplasty (TKA). We specifically evaluated: (1) perioperative surgical and medical complications; (2) lengths of stay (LOS); and (3) total hospital charges.
METHODS: The Nationwide Inpatient Sample was used to identify PD patients who underwent TKA between 2002 and 2013. To control for potential confounders, PD TKA and non-PD TKA patients were propensity score matched (1:3) based on age, sex, ethnicity, Charlson Comorbidity Index, and insurance type. A total of 31,979 PD and 95,596 non-PD TKA patients were included.
RESULTS: PD patients had a 44% higher risk of suffering from any complication (OR 1.44; 95% CI 1.35-1.54), a 45% increased risk for any medical complication (OR 1.45; 95% CI 1.36-1.55), and a 9% higher risk for any surgical complication (OR 1.09; 95% CI 0.84-1.41). Compared to the matched cohort, PD patients had a mean LOS that was 6.5% longer (95% CI 5.46-7.54) and mean total hospital charges that were 3.05% higher (95% CI 1.99-4.11).
CONCLUSIONS: PD patients are more likely to have postoperative complications, longer LOS, and higher costs after TKA than non-PD TKA patients. Since many of these complications can be prevented, a team-based multi-specialty patient optimization is needed. LEVEL OF EVIDENCE: Level III, therapeutic study.

Entities:  

Keywords:  Complications; Cost; Lengths of stay; Parkinson’s disease; Total knee arthroplasty

Mesh:

Year:  2018        PMID: 29785449     DOI: 10.1007/s00167-018-4970-y

Source DB:  PubMed          Journal:  Knee Surg Sports Traumatol Arthrosc        ISSN: 0942-2056            Impact factor:   4.342


  28 in total

1.  Postoperative complications in Parkinson's disease.

Authors:  P V Pepper; M K Goldstein
Journal:  J Am Geriatr Soc       Date:  1999-08       Impact factor: 5.562

Review 2.  Age-related bone loss: old bone, new facts.

Authors:  George K Chan; Gustavo Duque
Journal:  Gerontology       Date:  2002 Mar-Apr       Impact factor: 5.140

3.  Comorbid conditions associated with Parkinson's disease: a population-based study.

Authors:  Cynthia L Leibson; Demetrius M Maraganore; James H Bower; Jeanine E Ransom; Peter C O'brien; Walter A Rocca
Journal:  Mov Disord       Date:  2006-04       Impact factor: 10.338

Review 4.  Pathogenesis of bone fragility in women and men.

Authors:  Ego Seeman
Journal:  Lancet       Date:  2002-05-25       Impact factor: 79.321

5.  Admission of Parkinsonian patients to a neurological ward in a community hospital.

Authors:  Colin Klein; Tatiana Prokhorov; Ala Miniovitz; Eugenia Dobronevsky; Jose Martin Rabey
Journal:  J Neural Transm (Vienna)       Date:  2009-11       Impact factor: 3.575

6.  Total knee arthroplasty in patients with Parkinson's disease: impact of early postoperative neurologic intervention.

Authors:  Samir Mehta; Jonathan P Vankleunen; Robert E Booth; Paul A Lotke; Jess H Lonner
Journal:  Am J Orthop (Belle Mead NJ)       Date:  2008-10

7.  The Charlson comorbidity index is adapted to predict costs of chronic disease in primary care patients.

Authors:  Mary E Charlson; Robert E Charlson; Janey C Peterson; Spyridon S Marinopoulos; William M Briggs; James P Hollenberg
Journal:  J Clin Epidemiol       Date:  2008-07-10       Impact factor: 6.437

Review 8.  Parkinson's disease and the orthopaedic patient.

Authors:  Lee M Zuckerman
Journal:  J Am Acad Orthop Surg       Date:  2009-01       Impact factor: 3.020

9.  Parkinson's disease influences the perioperative risk profile in surgery.

Authors:  Marcus C Mueller; Ulf Jüptner; Ullrich Wuellner; Stefan Wirz; Andreas Türler; Andreas Hirner; Jens Standop
Journal:  Langenbecks Arch Surg       Date:  2008-08-19       Impact factor: 3.445

Review 10.  Postoperative delirium in the elderly: diagnosis and management.

Authors:  Thomas N Robinson; Ben Eiseman
Journal:  Clin Interv Aging       Date:  2008       Impact factor: 4.458

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  4 in total

1.  Sex Differences in Patterns of Sleep Disorders Among Hospitalizations With Parkinson's Disease: 2004-2014 Nationwide Inpatient Sample.

Authors:  Hind A Beydoun; Sharmin Hossain; Shuyan Huang; May A Beydoun; Brook T Alemu; Shaker M Eid; Alan B Zonderman
Journal:  Psychosom Med       Date:  2021-06-01       Impact factor: 3.864

2.  Functional outcomes after total joint arthroplasty are related to the severity of Parkinson's disease: a mid-term follow-up.

Authors:  Xiao Rong; Suraj Dahal; Ze-Yu Luo; Kai Zhou; Shun-Yu Yao; Zong-Ke Zhou
Journal:  J Orthop Surg Res       Date:  2019-11-28       Impact factor: 2.359

3.  Sagittal alignment changes and postoperative complications following surgery for adult spinal deformity in patients with Parkinson's disease: a multi-institutional retrospective cohort study.

Authors:  Atsuyuki Kawabata; Toshitaka Yoshii; Kenichiro Sakai; Takashi Hirai; Masato Yuasa; Hiroyuki Inose; Yu Matsukura; Shingo Morishita; Masaki Tomori; Ichiro Torigoe; Kazuo Kusano; Kazuyuki Otani; Yoshiyasu Arai; Shigeo Shindo; Atsushi Okawa
Journal:  BMC Musculoskelet Disord       Date:  2021-04-16       Impact factor: 2.362

Review 4.  Urinary Tract Infection in Parkinson's Disease.

Authors:  Elliot Hogg; Samuel Frank; Jillian Oft; Brian Benway; Mohammad Harun Rashid; Shouri Lahiri
Journal:  J Parkinsons Dis       Date:  2022       Impact factor: 5.520

  4 in total

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