Literature DB >> 29785260

COMBATING NRAS MUTANT MELANOMA: FROM BENCH TO BEDSIDE.

Ileabett M Echevarría-Vargas1, Jessie Villanueva1,2.   

Abstract

Entities:  

Keywords:  NRAS; clinical trials; drug combinations; immunotherapy; melanoma

Year:  2017        PMID: 29785260      PMCID: PMC5959291          DOI: 10.2217/mmt-2017-0023

Source DB:  PubMed          Journal:  Melanoma Manag        ISSN: 2045-0885


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6.  Binimetinib versus dacarbazine in patients with advanced NRAS-mutant melanoma (NEMO): a multicentre, open-label, randomised, phase 3 trial.

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9.  Inhibition of RAF Isoforms and Active Dimers by LY3009120 Leads to Anti-tumor Activities in RAS or BRAF Mutant Cancers.

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10.  Phase 1 trial of tivantinib in combination with sorafenib in adult patients with advanced solid tumors.

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3.  Classification and Grading of Melanocytic Lesions in a Mouse Model of NRAS-driven Melanomagenesis.

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  4 in total

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