Russell P Hayden1, Ryan Flannigan1, Peter N Schlegel2. 1. Department of Urology, Weill Cornell Medicine, 525 East 68th Street, Starr 900, New York, NY, 10065, USA. 2. Department of Urology, Weill Cornell Medicine, 525 East 68th Street, Starr 900, New York, NY, 10065, USA. pnschleg@med.cornell.edu.
Abstract
PURPOSE OF REVIEW: Increasing attention to primary and secondary prevention of male infertility through modifiable lifestyle factors has gained traction amongst both patients and infertility specialists. In this review, the available evidence of modifiable lifestyle choices, specifically diet, physical activity, and body habitus, are evaluated. RECENT FINDINGS: Studies examining diet, exercise/physical activity, and body habitus are characterized by conflicting conclusions, difficult confounders, and imperfect end points to judge male reproductive potential. However, convincing trends have emerged implicating consumption of saturated fats, pesticide exposure, high intensity exercise, and extremes of body mass index as detrimental to male fertility. Data assessing modifiable risk factors and subfertility in male partners has emphasized the notion of moderation. Balancing dietary fat, moderation of physical activity, and the management of a healthy body habitus favor both improvement of semen quality and birth outcomes. These observations provide actionable data for the reproductive urologist to better counsel men presenting with infertility.
PURPOSE OF REVIEW: Increasing attention to primary and secondary prevention of male infertility through modifiable lifestyle factors has gained traction amongst both patients and infertility specialists. In this review, the available evidence of modifiable lifestyle choices, specifically diet, physical activity, and body habitus, are evaluated. RECENT FINDINGS: Studies examining diet, exercise/physical activity, and body habitus are characterized by conflicting conclusions, difficult confounders, and imperfect end points to judge male reproductive potential. However, convincing trends have emerged implicating consumption of saturated fats, pesticide exposure, high intensity exercise, and extremes of body mass index as detrimental to male fertility. Data assessing modifiable risk factors and subfertility in male partners has emphasized the notion of moderation. Balancing dietary fat, moderation of physical activity, and the management of a healthy body habitus favor both improvement of semen quality and birth outcomes. These observations provide actionable data for the reproductive urologist to better counsel men presenting with infertility.
Entities:
Keywords:
Diet; Exercise; Lifestyle; Male infertility; Obesity
Authors: Lauren A Wise; Daniel W Cramer; Mark D Hornstein; Rachel K Ashby; Stacey A Missmer Journal: Fertil Steril Date: 2010-12-03 Impact factor: 7.329
Authors: Ana D Martins; Ana C Moreira; Rosália Sá; Mariana P Monteiro; Mário Sousa; Rui A Carvalho; Branca M Silva; Pedro F Oliveira; Marco G Alves Journal: Biochim Biophys Acta Date: 2015-06-10
Authors: T K Jensen; T B Henriksen; N H Hjollund; T Scheike; H Kolstad; A Giwercman; E Ernst; J P Bonde; N E Skakkebaek; J Olsen Journal: Reprod Toxicol Date: 1998 May-Jun Impact factor: 3.143
Authors: Haitham El Bardisi; Ahmad Majzoub; Mohamed Arafa; Ahmad AlMalki; Sami Al Said; Kareim Khalafalla; Gaby Jabbour; Moataz Basha; Abdulla Al Ansari; Edmund Sabanegh Journal: Reprod Biomed Online Date: 2016-08-20 Impact factor: 3.828
Authors: Tina K Jensen; Berit L Heitmann; Martin Blomberg Jensen; Thorhallur I Halldorsson; Anna-Maria Andersson; Niels E Skakkebæk; Ulla N Joensen; Mette P Lauritsen; Peter Christiansen; Christine Dalgård; Tina H Lassen; Niels Jørgensen Journal: Am J Clin Nutr Date: 2012-12-26 Impact factor: 7.045
Authors: Richard Michael Blay; Abigail Duah Pinamang; Augustine E Sagoe; Ewurama Dedea Ampadu Owusu; Nii Koney-Kwaku Koney; Benjamin Arko-Boham Journal: Int J Reprod Med Date: 2020-10-21
Authors: Jay Schinfeld; Fady Sharara; Randy Morris; Gianpiero D Palermo; Zev Rosenwaks; Eric Seaman; Steve Hirshberg; John Cook; Cristina Cardona; G Charles Ostermeier; Alexander J Travis Journal: Mol Reprod Dev Date: 2018-09-25 Impact factor: 2.609
Authors: Kristin I Stanford; Morten Rasmussen; Lisa A Baer; Adam C Lehnig; Leslie A Rowland; Joseph D White; Kawai So; Ana Luisa De Sousa-Coelho; Michael F Hirshman; Mary-Elizabeth Patti; Oliver J Rando; Laurie J Goodyear Journal: Diabetes Date: 2018-10-21 Impact factor: 9.461
Authors: Luana Mara Silva de Castro Pacheco da Cunha; Maria Yasmin Paz Teixeira; Ana Filomena Camacho Santos Daltro; Sebastião Evangelista Torquato; Renata Carmo de Assis; Roberta Freitas Celedonio; Liliane Viana Pires; Carla Soraya Costa Maia; Maria Izabel Florindo Guedes Journal: JBRA Assist Reprod Date: 2021-04-27