Tomoaki Murakami1. 1. Department of Cardiology, Chiba Children's Hospital, Chiba, Japan.
Abstract
BACKGROUND: In patients with aortic coarctation after successful aortic arch repair, it is well known that early-onset cardiovascular diseases can develop. SUMMARY: We studied the pressure waveform in patients after aortic arch repair focusing on a pressure wave reflection. In patients after aortic arch repair, the repaired portion generates a new reflected pressure wave. As a result, the newly generated pressure wave causes aortic pressure augmentation, loss of pressure amplification, and left ventricular hypertrophy with fibrosis. Balloon dilatation of the aortic arch may also generate a new pressure wave reflection. KEY MESSAGES: In patients with aortic coarctation after aortic arch repair, the reconstructed site generates a new pressure wave reflection. This could be one of the causes of their future cardiovascular diseases.
BACKGROUND: In patients with aortic coarctation after successful aortic arch repair, it is well known that early-onset cardiovascular diseases can develop. SUMMARY: We studied the pressure waveform in patients after aortic arch repair focusing on a pressure wave reflection. In patients after aortic arch repair, the repaired portion generates a new reflected pressure wave. As a result, the newly generated pressure wave causes aortic pressure augmentation, loss of pressure amplification, and left ventricular hypertrophy with fibrosis. Balloon dilatation of the aortic arch may also generate a new pressure wave reflection. KEY MESSAGES: In patients with aortic coarctation after aortic arch repair, the reconstructed site generates a new pressure wave reflection. This could be one of the causes of their future cardiovascular diseases.
Authors: Alberto P Avolio; Luc M Van Bortel; Pierre Boutouyrie; John R Cockcroft; Carmel M McEniery; Athanase D Protogerou; Mary J Roman; Michel E Safar; Patrick Segers; Harold Smulyan Journal: Hypertension Date: 2009-06-29 Impact factor: 10.190