| Literature DB >> 29760963 |
Tak Man Wong1, Frankie K L Leung1, Tak Wing Lau2, Christian Fang1, Felix H W Chan3, Jun Wu4.
Abstract
INTRODUCTION: The incidence of hip fracture is projected to increase in the next 25 years as the world population ages. Hip fracture is often associated with subsequent readmission and mortality. Nevertheless, elderly patients often may not achieve the same level of functional ability as prior to their injury. Several studies have shown that close collaboration between orthopedic surgeons and geriatricians can improve such outcomes and Geriatric Day Hospital (GDH) is one of the examples of collaboration to improve such outcomes. The aim of this descriptive retrospective study is to review the effectiveness of the day rehabilitation program provided by a GDH on functional outcomes, mortality, and readmission rate, among a sample of elderly patients with hip fracture.Entities:
Keywords: Geriatric Day Hospital (GDH); day rehabilitation program; functional outcomes; geriatric hip fractures; mortality; readmission
Year: 2018 PMID: 29760963 PMCID: PMC5946344 DOI: 10.1177/2151459318759355
Source DB: PubMed Journal: Geriatr Orthop Surg Rehabil ISSN: 2151-4585
Demographic Profile of Study Population.
| Demographic Variable | All (N = 253), n (%) |
|---|---|
| Gender | |
| Male | 61 (24.1%) |
| Female | 192 (75.9%) |
| Age (years) | |
| 60-69 | 8 (3.2%) |
| 70-79 | 71 (28.1%) |
| 80-89 | 140 (55.3%) |
| 90-99 | 33 (13.0%) |
| ≥100 | 1 (0.4%) |
| Premorbid ambulation status | |
| Walking without aid | 94 (37.2%) |
| Walking with aid | 159 (62.8%) |
| Smoking status | |
| Nonsmoker | 206 (81.4%) |
| Smoker or ex-smoker | 47 (18.6%) |
| Use of bisphosphonates | |
| Not used | 219 (86.6%) |
| Used | 34 (13.4%) |
| BI on admission | |
| 61-100 (slightly dependent or independent) | 214 (84.6%) |
| 41-60 (moderately dependent) | 19 (7.5%) |
| 0-40 (severely dependent) | 20 (7.9%) |
| EMS on admission | |
| 15-20 (independent) | 83 (32.7%) |
| 10-14 (moderately dependent) | 97 (38.3%) |
| 0-9 (severely dependent) | 73 (28.9%) |
| MMSE on admission | |
| 27-30 (normal) | 22 (8.7%) |
| 21-26 (slight) | 70 (27.7%) |
| 10-20 (moderate) | 140 (55.3%) |
| 0-9 (severe) | 21 (8.3%) |
| Charlson Comorbidity Index, mean (SD) | 2.4 (2.6) |
Abbreviations: BI, Barthel Index; EMS, Elderly Mobility Score; MMSE, Mini-Mental State Examination; SD, standard deviation.
Mean of RE, Physical, and Cognitive Measures Before and After Rehabilitation in GDH.
| Time Points for Evaluating Patients’ Outcomes | BI | EMS | MMSE |
|---|---|---|---|
| Mean score on admission, mean (SD) | 80.5 (19.8) | 12.1 (4.6) | 17.8 (6.2) |
| Mean score at discharge, mean (SD) | 83.2 (20.2) | 13.8 (4.9) | 19.1 (6.6) |
|
| .000 | .000 | .000 |
| Mean RE (%), mean (SD) | 22.5 (66.6), n = 233 | 27.1 (32.9), n = (240) | 12.3 (35.4), n = (251) |
Abbreviations: BI, Barthel Index; EMS, Elderly Mobility Score; GDH, Geriatric Day Hospital; MMSE, Mini-Mental State Examination; RE, rehabilitation effectiveness; SD, standard deviation.
Bivariate Analysis of RE and Various Variables.
| Demographic Variable | Mean RE by BI (%); n |
| Mean RE by EMS (%); n |
| Mean RE by MMSE (%); n |
|
|---|---|---|---|---|---|---|
| Gender | ||||||
| Male | 30.2 (46.1); 54 | – | 25.8 (32.8); 59 | – | 16.1 (30.3); 59 | – |
| Female | 20.2 (71.6); 179 | .334 | 27.5 (33.0); 181 | .719 | 11.2 (36.8); 192 | .346 |
| Age | ||||||
| 60-74 | 55.0 (39.1); 23 | – | 25.1 (36.2); 24 | – | 19.2 (72.7); 27 | – |
| 75-89 | 20.9 (68.3); 176 | .061 | 29.5 (33.8); 182 | .923 | 12.4 (29.2); 190 | .953 |
| ≥90 | 8.6 (67.1); 34 | .029a | 15.7 (22.5); 34 | .603 | 6.4 (18.8); 34 | .763 |
| Premorbid ambulation status | ||||||
| Walk without aid | 32.9 (56.6); 77 | – | 33.8 (37.9); 84 | – | 14.3 (44.5); 92 | – |
| Walk with aid | 17.4 (70.6); 156 | .095 | 23.5 (29.4); 156 | .033a | 11.2 (28.8); 159 | .505 |
| Charlson Comorbidity Index | ||||||
| 0 | 28.2 (77.9); 49 | – | 28.1 (30.9); 52 | – | 13.0 (35.1); 57 | – |
| 1-2 | 24.3 (53.1); 100 | 1.0 | 29.3 (34.5); 104 | 1.0 | 9.7 (40.0); 107 | 1.0 |
| >2 | 17.0 (74.0); 84 | 1.0 | 23.8 (32.2); 84 | 1.0 | 15.1 (29.5); 87 | 1.0 |
| Smoking status | ||||||
| Nonsmoker | 24.1 (57.6); 187 | .569 | 26.5 (32.3); 197 | .571 | 11.4 (37.0); 204 | .386 |
| Smoker or ex-smoker | 15.7 (95.3); 46 | 29.7 (35.9); 43 | 16.4 (27.3); 47 | |||
| Use of bisphosphonate | ||||||
| Bisphosphonates not used | 19.5 (69.8); 200 | .096 | 26.2 (32.2); 208 | .281 | 11.1 (36.4); 217 | .152 |
| Bisphosphonates used | 40.3 (38.0); 33 | 33.0 (37.0); 32 | 20.4 (26.5); 34 | |||
| Length of stay | ||||||
| ≤7 days | 22.0 (72.6); 201 | .849 | 27.3 (32.2) | .407 | 12.4 (36.3) | .874 |
| >7 days | 24.1 (36.6); 49 | 22.8 (33.2) | 11.5 (28.6) | |||
| BI on admission | ||||||
| 61-100 | 25.6 (71.9); 194 | – | 30.4 (34.0); 201 | – | 12.7 (37.6); 212 | – |
| 41-60 | 6.8 (27.9); 19 | .078 | 9.3 (17.5); 19 | .000a | 14.3 (23.0); 19 | 1.0 |
| 0-40 | 6.8 (15.5); 20 | .009a | 10.8 (21.2); 20 | .003a | 7.0 (14.3); 20 | 1.0 |
| EMS on admission | ||||||
| 15-20 | 48.6 (62.5); 66 | – | 39.6 (41.9); 70 | – | 17.4 (50.3); 81 | – |
| 10-14 | 12.6 (84.6); 94 | .007a | 28.6 (28.7); 97 | .171 | 13.6 (21.3); 97 | .893 |
| 0-9 | 11.5 (66.6); 73 | .000a | 13.1 (21.4); 73 | .000a | 5.0 (28.9); 73 | .171 |
| MMSE on admission | ||||||
| 27-30 | 36.2 (92.9); 15 | – | 30.2 (45.3); 19 | – | 0.8 (87.3); 20 | – |
| 21-26 | 34.8 (72.8); 62 | 1.000 | 37.5 (34.4); 64 | .988 | 21.2 (39.7); 70 | .904 |
| 10-20 | 16.9 (64.6); 135 | .971 | 24.0 (30.2); 136 | .994 | 10.8 (18.3); 140 | .997 |
| 0-9 | 11.9 (19.0); 21 | .913 | 12.9 (24.3); 21 | .623 | 12.3 (35.4); 21 | 1.0 |
Abbreviations: BI, Barthel Index; EMS, Elderly Mobility Score; MMSE, Mini-Mental State Examination; RE, rehabilitation effectiveness.
aSignificant difference (P < .05).
Outcomes of Patients Discharged From GDH.
| Outcomes | n (%) |
|---|---|
| Readmission | |
| Cumulative within 3 months | 15 (5.9%) |
| Cumulative within 6 months | 25 (9.9%) |
| Readmission specialty | |
| O&T | 3 (12%) |
| Other specialty | 22 (88%) |
| Refracture within 2 years | 15 (5.9%) |
| Mortality | |
| Within 3 months | 0 (0%) |
| Within 6 months | 0 (0%) |
| Within 1 year | 12 (4.7%) |
Abbreviations: GDH, Geriatric Day Hospital; O&T, orthopedics and traumatology.
Figure 1.Readmission specialties of patients’ readmission within 6 months. O&T indicates orthopedics and traumatology.
Risk Factors for Poor Outcomes (Cumulative Readmission Within 3 Months and 6 Months, Refracture Within 2 Years, and Cumulative Mortality Within 1 Year).
| Risk Factors | Readmission Within 3 Months (n = 15) |
| Readmission Within 6 Months (n = 25) |
| Refracture Within 2 Years |
| Cumulative Mortality Within 1 Year |
|
|---|---|---|---|---|---|---|---|---|
| Gender | ||||||||
| Male (61) | 4 (6.6%) | .811 | 8 (13.1%) | .331 | 3 (4.9%) | .701 | 6 (9.8%) |
|
| Female (192) | 11 (5.7%) | 17 (8.6%) | 12 (6.25%) | 6 (3.1%) | ||||
| Age | ||||||||
| 60-74 (28) | 0 (0%) | .225 | 1 (3.6%) | .458 | 0 (0%) | .146 | 0 (0%) | .129 |
| 75-89 (191) | 14 (7.3%) | 21 (11.0%) | 11 (5.8%) | 12 (6.3%) | ||||
| ≥90 (34) | 1 (2.9%) | 3 (8.8%) | 4 (11.8%) | 0 (0%) | ||||
| Premorbid ambulation status | ||||||||
| Walk without aid (94) | 5 (5.3%) | .752 | 8 (8.5%) | .574 | 5 (5.3%) | .752 | 3 (3.2%) | .372 |
| Walk with aid (159) | 10 (6.3%) | 17 (10.7%) | 10 (6.3%) | 9 (5.7%) | ||||
| Charlson Comorbidity Index | ||||||||
| 0 (57) | 1 (1.8%) | .283 | 2 (3.5%) | .186 | 4 (7.0%) | .734 | 1 (1.8%) | .052 |
| 1-2 (109) | 7 (6.4%) | 13 (11.9%) | 5 (4.6%) | 3 (2.8%) | ||||
| >2 (87) | 7 (8.0%) | 10 (11.5%) | 6 (6.9%) | 8 (9.2%) | ||||
| Smoking status | ||||||||
| Nonsmoker (206) | 12 (5.8%) | .884 | 18 (8.7%) | .202 | 13 (6.3%) | .590 | 10 (4.9%) | .862 |
| Smoker or ex-smoker (47) | 3 (6.4%) | 7 (14.9%) | 2 (4.3%) | 2 (4.3%) | ||||
| Use of bisphosphonate | ||||||||
| Bisphosphonates not used (219) | 12 (5.5%) | .442 | 20 (9.1%) | .311 | 12 (5.6%) | .442 | 10 (4.6%) | .737 |
| Bisphosphonates used (34) | 3 (8.8%) | 5 (14.7%) | 3 (8.8%) | 2 (5.9%) | ||||
| Length of stay | ||||||||
| ≤7 days (201) | 11 (5.5%) | .477 | 18 (9.0%) | .265 | 13 (6.5%) | .227 | 8 (4.0%) | .512 |
| >7 days (49) | 4 (8.2%) | 7 (14.3%) | 1 (2.0%) | 3 (6.1%) | ||||
| BI on admission | ||||||||
| 61-100 (214) | 14 (6.5%) | .503 | 20 (9.3%) | .244 | 12 (5.6%) | .723 | 2 (0.9%) |
|
| 41-60 (19) | 0 (0%) | 1 (5.3%) | 1 (5.3%) | 2 (10.5%) | ||||
| 0-40 (20) | 1 (5%) | 4 (20%) | 2 (10%) | 8 (40%) | ||||
| EMS on admission | ||||||||
| 15-20 (83) | 2 (2.4%) | .236 | 3 (3.6%) | .064 | 5 (6.0%) | .207 | 1 (1.2%) |
|
| 10-14 (97) | 8 (8.2%) | 13 (13.4%) | 3 (3.1%) | 4 (4.1%) | ||||
| 0-9 (73) | 5 (6.8%) | 9 (12.3%) | 7 (9.6%) | 7 (9.6%) | ||||
| MMSE on admission | ||||||||
| 27-30 (22) | 0 (0%) | .224 | 1 (4.5%) | .151 | 0 (0%) | .302 | 0 (0%) | .062 |
| 21-26 (70) | 2 (2.9%) | 3 (4.3%) | 6 (8.6%) | 1 (1.4%) | ||||
| 10-20 (140) | 12 (8.6%) | 19 (13.6%) | 9 (6.4%) | 8 (5.7%) | ||||
| 0-9 (21) | 1 (4.8%) | 2 (9.5%) | 0 (0%) | 3 (14.3%) | ||||
Abbreviations: BI, Barthel Index; EMS, Elderly Mobility Score; MMSE, Mini-Mental State Examination; RE, rehabilitation effectiveness.
aSignificant difference (P < .05).
Risk Factors for Outcomes of Patients Discharged From GDH.a
| Dependent | Variable | OR (95% CI) |
|
|---|---|---|---|
| Cumulative mortality within 12 months | BI on admission | 30.5 |
|
| Sex | 13.5 |
|
Abbreviations: CCI, Charlson Comorbidity Index; CI, confidence interval; EMS, Elderly Mobility Scale; GDH, Geriatric Day Hospital; OR, odds ratio.
aDependents were set as cumulative readmission within 3 and 6 months, refracture within 2 years, and cumulative mortality within 1 year. Controlling factors include gender, age, smoking status, use of bisphosphonates, CCI, BI on admission, EMS on admission, MMSE on admission, and premorbid ambulatory status.
*Significant difference because P value < 0.05.
Figure 2.Twelve-month mortalities of patients with different genders (A) and BI performance on admission (B). BI indicates Barthel Index.
Multivariate Analysis of RE.
| Variables | RE of BI | RE of EMS | RE of MMSE | |||
|---|---|---|---|---|---|---|
| β Coefficient |
| β Coefficient |
| β Coefficient |
| |
| Gender | 15.723 | .192 | −7.705 | .177 | 3.091 | .626 |
| Age (old [≥90] vs young [<90]) | −25.238 |
| −5.326 | .238 | −2.253 | .650 |
| Premorbid ambulation status (without aid vs with aid) | −10.325 | .289 | −4.245 | .359 | .133 | .979 |
| CCI (high vs low) | −2.328 | .700 | 1.048 | .716 | 2.560 | .421 |
| Smoking status | −21.989 | .077 | 4.069 | .502 | .058 | .993 |
| Use of bisphosphonate | 21.773 | .077 | 5.890 | .328 | 9.058 | .173 |
| Length of stay | 2.203 | .842 | −3.554 | .503 | −2.891 | .617 |
| BI on admission (low vs high) | −3.511 | .660 | −8.033 |
| 4.207 | .293 |
| EMS on admission (low vs high) | −12.595 | .073 | −8.821 |
| −8.084 | .433 |
| MMSE on admission (low vs high) | −0.757 | .915 | −0.645 |
| 0.639 | .864 |
Abbreviations: BI, Barthel Index; CCI, Charlson Comorbidity Index; EMS, Elderly Mobility Score; MMSE, Mini-Mental State Examination; RE, rehabilitation effectiveness.
*Significant difference because P value < 0.05.