Literature DB >> 29759851

The Role of Adiposity in the Association between Muscular Fitness and Cardiovascular Disease.

Alejandro Pérez-Bey1, Víctor Segura-Jiménez2, Jorge Del Rosario Fernández-Santos2, Irene Esteban-Cornejo3, Sonia Gómez-Martínez4, Oscar L Veiga5, Ascensión Marcos4, José Castro-Piñero2.   

Abstract

OBJECTIVES: To test the associations of muscular fitness and body mass index (BMI), individually and combined, with clustered cardiovascular disease risk factors in children and adolescents and to analyze the mediator role of BMI in the association between muscular fitness and clustered cardiovascular disease risk factors. STUDY
DESIGN: In total, 239 children (113 girls) and 270 adolescents (128 girls) participated in this cross-sectional study. Height and weight were assessed, and BMI was calculated. A cardiovascular disease risk factors index (CVDRF-I) was created from the combination of the following variables: waist circumference, systolic blood pressure, triglycerides, high-density lipoprotein cholesterol, and glucose. Handgrip strength/weight and standing long jump tests were used to assess muscular fitness. A muscular fitness index was computed from the combination of both tests.
RESULTS: Muscular fitness index was associated with CVDRF-I in children of both sexes and adolescent boys; however, these associations disappeared after accounting for BMI. BMI was associated with CVDRF-I in both children and adolescents, even after adjusting for muscular fitness (all P < .001). In male and female children and in adolescent boys, the association between muscular fitness and CVDRF-I was mediated by BMI (all P < .001). Because there was no association between muscular fitness and CVDRF-I in adolescent girls, the mediation hypothesis was discarded.
CONCLUSIONS: BMI is an independent predictor of CVDRF-I in children and adolescents of both sexes. Conversely, the effect of muscular fitness on CVDRF-I seems to be fully mediated by BMI levels in male and female children and in adolescent boys.
Copyright © 2018 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  adolescents; cardiometabolic risk factors; children; mediation analysis; muscular strength; weight status

Mesh:

Year:  2018        PMID: 29759851     DOI: 10.1016/j.jpeds.2018.03.071

Source DB:  PubMed          Journal:  J Pediatr        ISSN: 0022-3476            Impact factor:   4.406


  4 in total

1.  Muscular Fitness and Cardiometabolic Variables in Children and Adolescents: A Systematic Review.

Authors:  Tiago Rodrigues de Lima; Priscila Custódio Martins; Yara Maria Franco Moreno; Jean-Philippe Chaput; Mark Stephen Tremblay; Xuemei Sui; Diego Augusto Santos Silva
Journal:  Sports Med       Date:  2022-01-12       Impact factor: 11.928

2.  Health-related physical fitness indicators and clustered cardiometabolic risk factors in adolescents: A longitudinal study.

Authors:  Paula Roldão da Silva; Géssika Castilho Dos Santos; Jadson Marcio da Silva; Waynne Ferreira de Faria; Raphael Gonçalves de Oliveira; Antonio Stabelini Neto
Journal:  J Exerc Sci Fit       Date:  2020-06-18       Impact factor: 3.103

3.  Correlations between muscle strength and psychological health in Chinese adolescents: a cross-sectional analysis.

Authors:  Jinkui Lu; Hao Sun; Ningling Liu; Jianhua Qiu; Xiaofei Xia
Journal:  PeerJ       Date:  2022-10-06       Impact factor: 3.061

4.  Decreased Muscle-to-Fat Mass Ratio Is Associated with Low Muscular Fitness and High Alanine Aminotransferase in Children and Adolescent Boys in Organized Sports Clubs.

Authors:  Kai Ushio; Yukio Mikami; Hiromune Obayashi; Hironori Fujishita; Kouki Fukuhara; Tetsuhiko Sakamitsu; Kazuhiko Hirata; Yasunari Ikuta; Hiroaki Kimura; Nobuo Adachi
Journal:  J Clin Med       Date:  2021-05-24       Impact factor: 4.241

  4 in total

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