| Literature DB >> 29756573 |
Liyuan Hao1, Qiang Shan1, Jingya Wei1, Fengtao Ma1, Peng Sun1.
Abstract
Lactoferrin (lactotransferrin; Lf) is an iron-binding glycoprotein and one of the most important bioactivators in milk and other external secretions. It has numerous biological roles, including the regulation of iron absorption and modulation of immune responses, and has anti-microbial, anti-viral, antioxidant, anti-cancer, and anti-inflammatory activities. Lf regulates the quantity of iron absorbed in the intestine via its role in iron transport and can also chelate iron, directly or indirectly. Notably, it has been used as an adjuvant therapy for some intestinal diseases. It is now used in nutraceuticalsupplemented infant formula and other food products. This article reviews the content, distribution, physiologic functions and current applications of Lf, and aims to shed light on future prospects for additional applications of Lf. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.Entities:
Keywords: Lactoferrin (Lf); anti-cancer effect; anti-microbial effect; anti-viral effect; antioxidantzzm321990effect; application; immunomodulatory function; iron-binding activity.
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Year: 2019 PMID： 29756573 DOI： 10.2174/1389203719666180514150921
Source DB: PubMed Journal: Curr Protein Pept Sci ISSN： 1389-2037 Impact factor: 3.272