A Maugeri1, S Kunzova2, J R Medina-Inojosa3, A Agodi4, M Barchitta4, M Homolka2, N Kiacova2, H Bauerova2, O Sochor2, F Lopez-Jimenez3, M Vinciguerra5. 1. International Clinical Research Center, St Anne's University Hospital, Brno, Czech Republic; Department of Medical and Surgical Sciences and Advanced Technologies "GF Ingrassia", University of Catania, Catania, Italy. 2. International Clinical Research Center, St Anne's University Hospital, Brno, Czech Republic. 3. Department of Cardiovascular Medicine, Division of Preventive Cardiology, Mayo Clinic, Rochester MN, USA. 4. Department of Medical and Surgical Sciences and Advanced Technologies "GF Ingrassia", University of Catania, Catania, Italy. 5. International Clinical Research Center, St Anne's University Hospital, Brno, Czech Republic; Division of Medicine, University College London (UCL), London, UK. Electronic address: manlio.vinciguerra@fnusa.cz.
Abstract
BACKGROUND AND AIMS: The frequency and timing of meals may affect cardiovascular health (CVH) outcomes, but large-scale epidemiological studies are lacking. The aim of this study was to understand the relationship between eating time interval and frequency, and measures of ideal CVH in the Kardiovize Brno cohort study, a random urban sample population in Central Europe. METHODS AND RESULTS: 1659 members of the Kardiovize Brno 2030 cohort were included in a cross-sectional study (mean age = 46.86 years; 44.6% male). Exposure variables were eating time interval and frequency, and skipping meals. Primary outcomes were indices of CVH, including body mass index, diet, physical activity, smoking, blood pressure, glucose and cholesterol, and the composite CVH score. Cluster analysis and binary logistic regression analysis were used to evaluate eating habits and the association between variables. After adjustment for well-known risk factors, subjects who skipped breakfast or the afternoon snack had a higher risk of poor CVH (OR = 1.613; 95%CI = 1.121-2.320; p = 0.010; OR = 1.409; 95%CI = 1.110-1.788; p = 0.005, respectively). Moreover, we identified three clusters of individuals based on eating habits; from cluster 1 to cluster 3, eating time interval and frequency increased and this was associated with increases in CVH score from 8.70 (SEM = 0.10) in cluster 1, and 9.06 (SEM = 0.08) in cluster 2 to 9.42 (SEM = 0.09) in cluster 3 (p-trend = 0.019). CONCLUSIONS: Our findings suggest that skipping breakfast or the afternoon snack are risk factors for poor CVH, while higher eating time interval and frequency may promote ideal CVH.
BACKGROUND AND AIMS: The frequency and timing of meals may affect cardiovascular health (CVH) outcomes, but large-scale epidemiological studies are lacking. The aim of this study was to understand the relationship between eating time interval and frequency, and measures of ideal CVH in the Kardiovize Brno cohort study, a random urban sample population in Central Europe. METHODS AND RESULTS: 1659 members of the Kardiovize Brno 2030 cohort were included in a cross-sectional study (mean age = 46.86 years; 44.6% male). Exposure variables were eating time interval and frequency, and skipping meals. Primary outcomes were indices of CVH, including body mass index, diet, physical activity, smoking, blood pressure, glucose and cholesterol, and the composite CVH score. Cluster analysis and binary logistic regression analysis were used to evaluate eating habits and the association between variables. After adjustment for well-known risk factors, subjects who skipped breakfast or the afternoon snack had a higher risk of poor CVH (OR = 1.613; 95%CI = 1.121-2.320; p = 0.010; OR = 1.409; 95%CI = 1.110-1.788; p = 0.005, respectively). Moreover, we identified three clusters of individuals based on eating habits; from cluster 1 to cluster 3, eating time interval and frequency increased and this was associated with increases in CVH score from 8.70 (SEM = 0.10) in cluster 1, and 9.06 (SEM = 0.08) in cluster 2 to 9.42 (SEM = 0.09) in cluster 3 (p-trend = 0.019). CONCLUSIONS: Our findings suggest that skipping breakfast or the afternoon snack are risk factors for poor CVH, while higher eating time interval and frequency may promote ideal CVH.
Authors: Andrea Maugeri; Jose R Medina-Inojosa; Sarka Kunzova; Antonella Agodi; Martina Barchitta; Ondrej Sochor; Francisco Lopez-Jimenez; Yonas E Geda; Manlio Vinciguerra Journal: Nutrients Date: 2018-09-03 Impact factor: 5.717
Authors: Andrea Maugeri; Jose R Medina-Inojosa; Sarka Kunzova; Martina Barchitta; Antonella Agodi; Manlio Vinciguerra; Francisco Lopez-Jimenez Journal: Mayo Clin Proc Innov Qual Outcomes Date: 2019-08-23
Authors: Sarka Kunzova; Andrea Maugeri; Jose Medina-Inojosa; Francisco Lopez-Jimenez; Manlio Vinciguerra; Pedro Marques-Vidal Journal: Front Public Health Date: 2020-04-08
Authors: Antonella Agodi; Andrea Maugeri; Sarka Kunzova; Ondrej Sochor; Hana Bauerova; Nikola Kiacova; Martina Barchitta; Manlio Vinciguerra Journal: Nutrients Date: 2018-07-13 Impact factor: 5.717