Literature DB >> 29749701

The relationship of renal function to segmental vascular stiffness, ankle-brachial index, and peripheral artery disease.

Yueh-Hung Lin1,2, Kuo-Tzu Sung1,2, Cheng-Ting Tsai1,2, Pei-Chen Wu3, Yau-Huei Lai1,4,5, Chi-In Lo1,2, Fa-Chang Yu1,2, Hsu-Ping Wu1,5, Wei-Ran Lan1,2, Jen-Yuan Kuo1,2,4, Charles Jia-Yin Hou1,2,4, Chi-Hsuan Yen1,2,4, Ming-Cheng Peng1,2, Ta-Chuan Hung1,2,4, Chung-Lieh Hung1,2,6, Edward Lai7, Hung-I Yeh1,2.   

Abstract

The authors consecutively assessed various arterial pulse-wave velocity (PWV) indices and ankle-brachial index (ABI) by an automatic device (VP2000, OMRON Health Care Co. Ltd., Kyota, Japan) in outpatients with ≥ 1 cardiovascular risk. PAD was defined as ABI ≤ 0.9. Among 2309 outpatients (mean age 62.4 years), worse renal function was associated with higher brachial-ankle PWV, heart-carotid PWV, heart-femoral PWV (hf-PWV), and lower ABI (all P < .001). Multivariate regression models showed independent associations between lower eGFR, lower ABI (Coef: 0.42 & 0.41 for right and left), higher hf-PWV (Coef: -11.4 [95% CI: -15.4, -7.3]) and greater PAD risk (adjusted OR: 0.83 [95% CI: 0.76, 0.91], all P < .05). eGFR set at 77 mL/min/1.73m2 was observed to be useful clinical cutoff (c-statistics: 0.67) for identifying PAD (P for ΔAUROC: .009; likelihood X2 : 93.82 to 137.43, P < .001) when superimposed on clinical risks. This study suggested early renal insufficiency is tightly linked to region-specific vascular stiffness and PAD. ©2018 Wiley Periodicals, Inc.

Entities:  

Keywords:  ankle-brachial index; peripheral artery disease; pulse-wave velocity; renal insufficiency; vascular stiffness

Mesh：

Year:  2018        PMID： 29749701      PMCID： PMC8031290          DOI： 10.1111/jch.13297

Source DB:  PubMed          Journal:  J Clin Hypertens (Greenwich)        ISSN： 1524-6175            Impact factor:   3.738


  44 in total

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Journal:  Diabetes Care       Date:  2015-01       Impact factor: 19.112

4.  Kidney function and risk of peripheral arterial disease: results from the Atherosclerosis Risk in Communities (ARIC) Study.

Authors:  Keattiyoat Wattanakit; Aaron R Folsom; Elizabeth Selvin; Josef Coresh; Alan T Hirsch; Beth D Weatherley
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Review 6.  Arterial Stiffness: A Novel Risk Factor for Kidney Injury Progression?

Authors:  Panagiotis I Georgianos; Pantelis A Sarafidis; Vassilios Liakopoulos
Journal:  Am J Hypertens       Date:  2015-02-15       Impact factor: 2.689

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Authors:  A S Levey; J P Bosch; J B Lewis; T Greene; N Rogers; D Roth
Journal:  Ann Intern Med       Date:  1999-03-16       Impact factor: 25.391

8.  Walking disability in patients with peripheral artery disease is associated with arterial endothelial function.

Authors:  S Marlene Grenon; Karen Chong; Hugh Alley; Emily Nosova; Warren Gasper; Jade Hiramoto; W John Boscardin; Christopher D Owens
Journal:  J Vasc Surg       Date:  2014-01-11       Impact factor: 4.268

9.  Advanced peripheral microvascular endothelial dysfunction and polyvascular disease in patients with high cardiovascular risk.

Authors:  Hirofumi Maeda; Seigo Sugiyama; Hideaki Jinnouchi; Yasushi Matsuzawa; Koichiro Fujisue; Yoshihiro Hirata; Hirofumi Kurokawa; Keisuke Ohba; Junichi Matsubara; Toshimitsu Nozaki; Masaaki Konishi; Eiichi Akiyama; Koichi Sugamura; Eiichiro Yamamoto; Hitoshi Sumida; Hisao Ogawa
Journal:  J Cardiol       Date:  2015-09-04       Impact factor: 3.159

10.  Development and validation of an ankle brachial index risk model for the prediction of cardiovascular events.

Authors:  F G R Fowkes; G D Murray; I Butcher; A R Folsom; A T Hirsch; D J Couper; G Debacker; M Kornitzer; A B Newman; K C Sutton-Tyrrell; M Cushman; A J Lee; J F Price; R B D'Agostino; J M Murabito; Pe Norman; K H Masaki; L M Bouter; R J Heine; C D A Stehouwer; M M McDermott; H E J H Stoffers; J A Knottnerus; M Ogren; B Hedblad; W Koenig; C Meisinger; J A Cauley; Oh Franco; M G M Hunink; A Hofman; J C Witteman; M H Criqui; R D Langer; W R Hiatt; R F Hamman
Journal:  Eur J Prev Cardiol       Date:  2013-12-23       Impact factor: 7.804
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  1 in total

1.  The relationship of renal function to segmental vascular stiffness, ankle-brachial index, and peripheral artery disease.

Authors:  Yueh-Hung Lin; Kuo-Tzu Sung; Cheng-Ting Tsai; Pei-Chen Wu; Yau-Huei Lai; Chi-In Lo; Fa-Chang Yu; Hsu-Ping Wu; Wei-Ran Lan; Jen-Yuan Kuo; Charles Jia-Yin Hou; Chi-Hsuan Yen; Ming-Cheng Peng; Ta-Chuan Hung; Chung-Lieh Hung; Edward Lai; Hung-I Yeh
Journal:  J Clin Hypertens (Greenwich)       Date:  2018-05-11       Impact factor: 3.738
  1 in total

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