Literature DB >> 29746626

Association of Cutibacterium avidum Colonization in the Groin With Obesity: A Potential Risk Factor for Hip Periprosthetic Joint Infection.

Laura Böni1, Stefan P Kuster1, Bianka Bartik2, Reinhard Zbinden3, Patrick O Zingg2, Yvonne Achermann1.   

Abstract

Background: An increase in the incidence of hip periprosthetic joint infections caused by Cutibacterium avidum has recently been detected after hip arthroplasty with an anterior surgical approach. We raised the question of whether skin colonization with C. avidum differs between the anterior and the lateral thigh as areas of surgical incision fields.
Methods: Between February and June 2017, we analyzed skin scrapings from the groin and the anterior and lateral thigh in patients undergoing a primary hip arthroplasty. We anaerobically cultured plated swab samples for Cutibacterium spp. for ≥7 days. Univariate logistic regression analysis was used to explore associations between body mass index (BMI) and colonization rate at different sites.
Results: Twenty-one of 65 patients (32.3%) were colonized with C. avidum at any site, mainly at the groin (n = 16; 24.6%), which was significantly higher at the anterior (n = 5; 7.7%; P = .009) or lateral (n = 6; 9.2%; P = .02) thigh. Patients colonized with C. avidum did not differ from noncolonized patients in age or sex, but their BMIs were significantly higher (30.1 vs 25.6 kg/m2, respectively; P = .02). Furthermore, increased BMI was associated with colonization at the groin (odds ratio per unit BMI increase, 1.15; 95% confidence interval; 1.03-1.29; P = .01). Conclusions: The groin, rather than the anterior thigh, showed colonization for C. avidum in obese patients. Further studies are needed to evaluate current skin disinfection and draping protocols for hip arthroplasty, particularly in obese patients.

Entities:  

Mesh:

Year:  2018        PMID: 29746626     DOI: 10.1093/cid/ciy379

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN: 1058-4838            Impact factor:   9.079


  4 in total

1.  Fracture Related Infections and Their Risk Factors for Treatment Failure-A Major Trauma Centre Perspective.

Authors:  Victor Lu; James Zhang; Ravi Patel; Andrew Kailin Zhou; Azeem Thahir; Matija Krkovic
Journal:  Diagnostics (Basel)       Date:  2022-05-22

2.  Obese patients have higher rates of polymicrobial and Gram-negative early periprosthetic joint infections of the hip than non-obese patients.

Authors:  Claudia A M Löwik; Wierd P Zijlstra; Bas A S Knobben; Joris J W Ploegmakers; Baukje Dijkstra; Astrid J de Vries; Greetje A Kampinga; Glen Mithoe; Aziz Al Moujahid; Paul C Jutte; Marjan Wouthuyzen-Bakker
Journal:  PLoS One       Date:  2019-04-08       Impact factor: 3.240

3.  Cutibacterium avidum resists surgical skin antisepsis in the groin-a potential risk factor for periprosthetic joint infection: a quality control study.

Authors:  Steven M Maurer; Laura Kursawe; Stefan Rahm; Julia Prinz; Annelies S Zinkernagel; Annette Moter; Stefan P Kuster; Reinhard Zbinden; Patrick O Zingg; Yvonne Achermann
Journal:  Antimicrob Resist Infect Control       Date:  2021-02-01       Impact factor: 4.887

4.  Differential microbiological spectrum and resistance pattern in periprosthetic hip joint infections: a matched-cohort analysis comparing direct anterior versus lateral approach.

Authors:  Alexander Aichmair; Bernhard J H Frank; Gabriel Singer; Sebastian Simon; Martin Dominkus; Jochen G Hofstaetter
Journal:  BMC Musculoskelet Disord       Date:  2022-01-19       Impact factor: 2.362

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.