Literature DB >> 29744828

ATR-FTIR Analysis of Amyloid Proteins.

Jean-Marie Ruysschaert1, Vincent Raussens2.   

Abstract

Attenuated total reflection FTIR (ATR-FTIR) has been used for decades to study protein secondary structures. More recently, it reveals also to be an exquisite and sensitive tool to study and discriminate amyloid aggregates. Based on the analysis of specific spectral features of β-sheet structures, we present here a detailed protocol to differentiate oligomers vs. fibrils. This protocol, applicable to all amyloid proteins, demonstrates the power of this inexpensive, rapid, and low protein material-demanding method.

Keywords:  ATR; Aggregates; Amyloid; FTIR; Fibrils; Oligomers; Structure

Mesh：

Substances：

Year:  2018        PMID： 29744828     DOI： 10.1007/978-1-4939-7811-3_3

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  9 in total

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Journal:  Methods Mol Biol       Date:  2022

3.  Characterization by Nano-Infrared Spectroscopy of Individual Aggregated Species of Amyloid Proteins.

Authors:  Jehan Waeytens; Vincent Van Hemelryck; Ariane Deniset-Besseau; Jean-Marie Ruysschaert; Alexandre Dazzi; Vincent Raussens
Journal:  Molecules       Date:  2020-06-24       Impact factor: 4.411

4.  RNA recognition motifs of disease-linked RNA-binding proteins contribute to amyloid formation.

Authors:  Sashank Agrawal; Pan-Hsien Kuo; Lee-Ya Chu; Bagher Golzarroshan; Monika Jain; Hanna S Yuan
Journal:  Sci Rep       Date:  2019-04-16       Impact factor: 4.379

5.  Bioinformatics methods for identification of amyloidogenic peptides show robustness to misannotated training data.

Authors:  Michał Burdukiewicz; Malgorzata Kotulska; Natalia Szulc; Marlena Gąsior-Głogowska; Jakub W Wojciechowski; Jarosław Chilimoniuk; Paweł Mackiewicz; Tomas Šneideris; Vytautas Smirnovas
Journal:  Sci Rep       Date:  2021-04-26       Impact factor: 4.379

6.  Searching for universal model of amyloid signaling motifs using probabilistic context-free grammars.

Authors:  Marlena Gąsior-Głogowska; Monika Szefczyk; Witold Dyrka; Natalia Szulc
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7.  Origin, toxicity and characteristics of two amyloid oligomer polymorphs.

Authors:  Chamani Niyangoda; Jeremy Barton; Nabila Bushra; Kanchana Karunarathne; Graham Strauss; Fadia Fakhre; Piyush Koria; Martin Muschol
Journal:  RSC Chem Biol       Date:  2021-08-25

8.  Unraveling Membrane Perturbations Caused by the Bacterial Riboregulator Hfq.

Authors:  Florian Turbant; Jehan Waeytens; Camille Campidelli; Marianne Bombled; Denis Martinez; Axelle Grélard; Birgit Habenstein; Vincent Raussens; Marisela Velez; Frank Wien; Véronique Arluison
Journal:  Int J Mol Sci       Date:  2022-08-05       Impact factor: 6.208

9.  Variability of Amyloid Propensity in Imperfect Repeats of CsgA Protein of Salmonella enterica and Escherichia coli.

Authors:  Natalia Szulc; Marlena Gąsior-Głogowska; Jakub W Wojciechowski; Monika Szefczyk; Andrzej M Żak; Michał Burdukiewicz; Malgorzata Kotulska
Journal:  Int J Mol Sci       Date:  2021-05-12       Impact factor: 5.923
  9 in total

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