Literature DB >> 29733733

Characteristics Of Likely Precision Medicine Initiative Participants Drawn From A Large Blood Donor Population.

Cinnamon S Bloss1, Justin Stoler2, Cynthia E Schairer3, Sara B Rosenthal4, Cynthia Cheung5, Holly M Rus6, Jessica L Block7, Jiue-An Jay Yang8, Doug Morton9, Helen Bixenman10, David Wellis11.   

Abstract

A goal of the Precision Medicine Initiative All of Us Research Program (AoURP) is recruitment of participants who reflect the diversity of the US. Recruitment from among blood bank donors, which may better reflect the demographic makeup of local communities, is one proposed strategy. We evaluated this strategy by analyzing the results of a survey of San Diego Blood Bank donors conducted in November 2015. Whites were more likely than nonwhites to respond to the survey (7.1 percent versus 3.9 percent). However, race was not a significant predictor of interest in participating in precision medicine research. Using census data linked to donors' ZIP codes, we also found that people who indicated interest in research participation were more likely to come from regions with higher educational attainment. Although blood banks represent a viable recruitment strategy for AoURP, our findings indicate that bias toward inclusion of whites and more highly educated people persists.

Entities:  

Keywords:  Disparities; Genetics; Genomics; Precision Medicine; Public Health

Mesh:

Year:  2018        PMID: 29733733     DOI: 10.1377/hlthaff.2017.1591

Source DB:  PubMed          Journal:  Health Aff (Millwood)        ISSN: 0278-2715            Impact factor:   6.301


  5 in total

1.  A roadmap for precision medicine research recruitment: empirical assessment of the public's willingness to participate.

Authors:  Kelsey Moriarty; Susan M Wolf; Patricia M Veach; Bonnie LeRoy; Ian M MacFarlane; Heather A Zierhut
Journal:  Per Med       Date:  2020-08-17       Impact factor: 2.512

2.  Interest in Cancer Predisposition Testing and Carrier Screening Offered as Part of Routine Healthcare Among an Ethnically Diverse Sample of Young Women.

Authors:  Kimberly A Kaphingst; Jemar R Bather; Brianne M Daly; Daniel Chavez-Yenter; Alexis Vega; Wendy K Kohlmann
Journal:  Front Genet       Date:  2022-04-14       Impact factor: 4.772

3.  ChicagO Multiethnic Prevention and Surveillance Study (COMPASS): Increased Response Rates Among African American Residents in Low Socioeconomic Status Neighborhoods.

Authors:  David J Press; Briseis Aschebrook-Kilfoy; Diane Lauderdale; Elizabeth Stepniak; Scarlett Lin Gomez; Emily Peterson Johnson; Rajan Gopalakrishnan; Fabrice Smieliauskas; Donald Hedeker; Luís Bettencourt; Luc Anselin; Habibul Ahsan
Journal:  J Racial Ethn Health Disparities       Date:  2020-06-15

4.  State of recent literature on communication about cancer genetic testing among Latinx populations.

Authors:  Daniel Chavez-Yenter; Wen-Ying Sylvia Chou; Kimberly A Kaphingst
Journal:  J Genet Couns       Date:  2020-11-03       Impact factor: 2.717

5.  The role of race and ethnicity in views toward and participation in genetic studies and precision medicine research in the United States: A systematic review of qualitative and quantitative studies.

Authors:  Elena R Fisher; Rebekah Pratt; Riley Esch; Megan Kocher; Katie Wilson; Whiwon Lee; Heather A Zierhut
Journal:  Mol Genet Genomic Med       Date:  2019-12-23       Impact factor: 2.183

  5 in total

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