Literature DB >> 29721976

Pigment Epithelium-derived Factor Protects Retinal Pigment Epithelial Cells Against Cytotoxicity "In Vitro".

Francisco M Nadal-Nicolas1, S Patricia Becerra2.   

Abstract

Oxidative stress has been implicated in neurodegenerative diseases, such as age-related macular degeneration. Hydrogen peroxide and sodium iodate can mediate oxidative injury. Sodium iodate induces a selective retinal degeneration targeting the RPE. We describe a method of chronic sodium iodate-mediated injury on RPE cells that may serve to evaluate protective factors against oxidative stress. Cytotoxicity and cell viability curves of ARPE-19 cells with sodium iodate were generated. The antioxidant pigment epithelium-derived factor decreased sodium iodate-mediated cytotoxicity without affecting ARPE-19 cell viability. A cell culture system to evaluate protection against oxidative stress injury with PEDF is discussed.

Entities:  

Keywords:  ARPE-19 cells; Age-related macular degeneration; Oxidative stress; Pigment epithelium-derived factor (PEDF); Retinal pigment epithelium (RPE); Sodium iodate (NaIO3); Toxicity; Viability

Mesh：

Substances：

Year:  2018        PMID： 29721976      PMCID： PMC6172950          DOI： 10.1007/978-3-319-75402-4_56

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN： 0065-2598            Impact factor:   2.622


  31 in total

Review 1.  Oxidative damage and protection of the RPE.

Authors:  J Cai; K C Nelson; M Wu; P Sternberg; D P Jones
Journal:  Prog Retin Eye Res       Date:  2000-03       Impact factor: 21.198

2.  Pigment epithelium-derived factor exerts antioxidative effects in granulosa cells.

Authors:  Hadas Bar-Joseph; Ido Ben-Ami; Raphael Ron-El; Ruth Shalgi; Dana Chuderland
Journal:  Fertil Steril       Date:  2014-07-23       Impact factor: 7.329

3.  PEDF Promotes Biosynthesis of a Novel Anti-inflammatory and Anti-apoptotic Mediator NPD1 in Retinal Pigment Epithelial Cells.

Authors:  Maria A Reinoso; Pranab Mukherjee; Victor Marcheselli; Donald Bergsma; Richard Hesse; Nicolas Bazan
Journal:  Ochsner J       Date:  2008

Review 4.  Pigment Epithelium-Derived Factor, a Protective Factor for Photoreceptors in Vivo.

Authors:  Federica Polato; S Patricia Becerra
Journal:  Adv Exp Med Biol       Date:  2016       Impact factor: 2.622

5.  Direct effect of sodium iodate on neurosensory retina.

Authors:  Jinmei Wang; Jared Iacovelli; Carrie Spencer; Magali Saint-Geniez
Journal:  Invest Ophthalmol Vis Sci       Date:  2014-03-28       Impact factor: 4.799

6.  The prevalence of age-related maculopathy: the visual impairment project.

Authors:  M R VanNewkirk; M B Nanjan; J J Wang; P Mitchell; H R Taylor; C A McCarty
Journal:  Ophthalmology       Date:  2000-08       Impact factor: 12.079

Review 7.  The effects of PEDF on cancer biology: mechanisms of action and therapeutic potential.

Authors:  S Patricia Becerra; Vicente Notario
Journal:  Nat Rev Cancer       Date:  2013-03-14       Impact factor: 60.716

8.  Loss of DJ-1 elicits retinal abnormalities, visual dysfunction, and increased oxidative stress in mice.

Authors:  Vera L Bonilha; Brent A Bell; Mary E Rayborn; Xiaoping Yang; Charlie Kaul; Gregory H Grossman; Ivy S Samuels; Joe G Hollyfield; Chengsong Xie; Huaibin Cai; Karen G Shadrach
Journal:  Exp Eye Res       Date:  2015-07-26       Impact factor: 3.467

9.  Noninvasive imaging of the early effect of sodium iodate toxicity in a rat model of outer retina degeneration with spectral domain optical coherence tomography.

Authors:  Sepideh Hariri; Man Chun Tam; Donghyun Lee; Denise Hileeto; Alireza Akhlagh Moayed; Kostadinka Bizheva
Journal:  J Biomed Opt       Date:  2013-02       Impact factor: 3.170

Review 10.  PEDF: anti-angiogenic guardian of ocular function.

Authors:  Noël Bouck
Journal:  Trends Mol Med       Date:  2002-07       Impact factor: 11.951
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  6 in total

1.  PEDF deficiency increases the susceptibility of rd10 mice to retinal degeneration.

Authors:  Shivani Dixit; Federica Polato; Marijana Samardzija; Mones Abu-Asab; Christian Grimm; Susan E Crawford; S Patricia Becerra
Journal:  Exp Eye Res       Date:  2020-07-25       Impact factor: 3.467

2.  New anti-angiogenic compound based on chemically modified heparin.

Authors:  Vinicius Kniggendorf; Maria Eduarda Perrud Souza; Thatiane Russo; Marcelo Andrade de Lima; Alex Treiger Grupenmacher; Caio V Regatieri; Juliana L Dreyfuss
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2022-09-13       Impact factor: 3.535

3.  Tetramethylpyrazine protects mice retinas against sodium iodate-induced oxidative injury.

Authors:  Jie Huang; Yan Liu; Ke Mao; Qing Gu; Xingwei Wu
Journal:  Mol Vis       Date:  2020-06-27       Impact factor: 2.367

4.  Potential Protective Role of TRPM7 and Involvement of PKC/ERK Pathway in Blue Light-Induced Apoptosis in Retinal Pigment Epithelium Cells in Vitro.

Authors:  Luping Hu; Guoxing Xu
Journal:  Asia Pac J Ophthalmol (Phila)       Date:  2021-11-16

5.  ARPE-19 conditioned medium promotes neural differentiation of adipose-derived mesenchymal stem cells.

Authors:  Giuliana Mannino; Martina Cristaldi; Giovanni Giurdanella; Rosario Emanuele Perrotta; Debora Lo Furno; Rosario Giuffrida; Dario Rusciano
Journal:  World J Stem Cells       Date:  2021-11-26       Impact factor: 5.326

6.  Pigment Epithelium-Derived Factor-Loaded PEGylated Nanoparticles as a New Antiangiogenic Therapy for Neovascularization.

Authors:  Feng Zhao; Wenlei Fei; Zhouyue Li; Hanyang Yu; Lei Xi
Journal:  J Diabetes Res       Date:  2022-04-22       Impact factor: 4.061
  6 in total

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