Literature DB >> 29719843

Diagnosis of Appendicitis in Patients with a Normal White Blood Cell Count; A Cross-Sectional Study.

Sadettin Er1, Bülent Çomçalı1, Ahmet Soykurt1, Bülent Cavit Yüksel1, Mesut Tez1.   

Abstract

OBJECTIVE: To investigate the clinical, imaging and laboratory findings for diagnosis of acute appendicitis (AA) in patients with a normal white blood cell count (WBCC).
METHODS: This retrospective cross-sectional study was conducted in Ankara Numune Training and Research Hospital, Ankara, Turkey, during a 1-year period. To determine diagnostic factors in AA in patients with normal WBCC, medical records of eligible patients were reviewed for demographic and clinical variables, as well as patient outcome.
RESULTS: A total of 105 patients that had undergone appendectomy and were found to have a normal WBCC were included in the study. Of these patients, 53 (50.5%) were men and 52 (49.5%) were women. The mean age of the patients was 34.2±12.3 (min 14, max 78). The negative exploration rate was identified as 19%. In the multivariate analysis, only the diameter of appendix was statistically significant (p=0.002). ROC analysis revealed the cut off appendiceal diameter as 8 mm.
CONCLUSION: In patients suspected of AA due to ≥8 mm appendiceal diameter determined by imaging, we recommend surgical treatment even if WBCC and neutrophil count are normal.

Entities:  

Keywords:  Acute appendicitis; Appendix diameter; Diagnosis; White blood cell count

Year:  2018        PMID: 29719843      PMCID: PMC5928269          DOI: 10.29252/beat-060207

Source DB:  PubMed          Journal:  Bull Emerg Trauma        ISSN: 2322-2522


  23 in total

Review 1.  Infectious causes of appendicitis.

Authors:  Laura W Lamps
Journal:  Infect Dis Clin North Am       Date:  2010-12       Impact factor: 5.982

2.  A practical score for the early diagnosis of acute appendicitis.

Authors:  A Alvarado
Journal:  Ann Emerg Med       Date:  1986-05       Impact factor: 5.721

3.  Ultrasonography in diagnosis of acute appendicitis.

Authors:  Faik Tatli; Ugur Ekici; Murat Kanlioz; Orhan Gozeneli; Ali Uzunkoy; Yusuf Yucel; Abuzer Dirican
Journal:  Ann Ital Chir       Date:  2016       Impact factor: 0.766

4.  Predictive factors and outcomes of negative appendectomy.

Authors:  Byeong Geon Jeon
Journal:  Am J Surg       Date:  2016-07-28       Impact factor: 2.565

5.  False-negative and false-positive errors in abdominal pain evaluation: failure to diagnose acute appendicitis and unnecessary surgery.

Authors:  L Graff; J Russell; J Seashore; J Tate; A Elwell; M Prete; M Werdmann; R Maag; C Krivenko; M Radford
Journal:  Acad Emerg Med       Date:  2000-11       Impact factor: 3.451

6.  Less negative appendectomies due to imaging in patients with suspected appendicitis.

Authors:  P A Boonstra; R N van Veen; H B A C Stockmann
Journal:  Surg Endosc       Date:  2014-12-05       Impact factor: 4.584

7.  Association of viral infection and appendicitis.

Authors:  Adam C Alder; Thomas B Fomby; Wayne A Woodward; Robert W Haley; George Sarosi; Edward H Livingston
Journal:  Arch Surg       Date:  2010-01

8.  Incidence of normal white cell count and C-reactive protein in adults with acute appendicitis.

Authors:  Nalin H Dayawansa; Julian D S Segan; Henry H I Yao; Hon I Chong; Paul J Sitzler
Journal:  ANZ J Surg       Date:  2016-09-14       Impact factor: 1.872

9.  The clinical and economic correlates of misdiagnosed appendicitis: nationwide analysis.

Authors:  David R Flum; Thomas Koepsell
Journal:  Arch Surg       Date:  2002-07

Review 10.  Meta-analysis of the clinical and laboratory diagnosis of appendicitis.

Authors:  R E B Andersson
Journal:  Br J Surg       Date:  2004-01       Impact factor: 6.939

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  1 in total

1.  The Dynamics of Inflammatory Markers in Patients with Suspected Acute Appendicitis.

Authors:  Ąžuolas Algimantas Kaminskas; Raminta Lukšaitė-Lukštė; Eugenijus Jasiūnas; Artūras Samuilis; Vytautas Augustinavičius; Marius Kryžauskas; Kęstutis Strupas; Tomas Poškus
Journal:  Medicina (Kaunas)       Date:  2021-12-20       Impact factor: 2.430

  1 in total

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