Literature DB >> 29719230

Asparagine and Glutamine: Co-conspirators Fueling Metastasis.

Ming Luo1, Michael Brooks2, Max S Wicha3.   

Abstract

Cancer cells frequently hijack normal metabolic pathways to promote their growth and metastasis. Two recent papers by Knott et al. (2018) and Pavlova et al. (2018) demonstrate that asparagine and glutamine work in concert to drive tumor growth and metastasis through modulation of cell survival, growth, and EMT regulatory pathways.
Copyright © 2018. Published by Elsevier Inc.

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Year:  2018        PMID： 29719230     DOI： 10.1016/j.cmet.2018.04.012

Source DB:  PubMed          Journal:  Cell Metab        ISSN： 1550-4131            Impact factor:   27.287


  21 in total

1.  Glutamine and asparagine activate mTORC1 independently of Rag GTPases.

Authors:  Delong Meng; Qianmei Yang; Huanyu Wang; Chase H Melick; Rishika Navlani; Anderson R Frank; Jenna L Jewell
Journal:  J Biol Chem       Date:  2020-02-04       Impact factor: 5.157

2.  Selective glutamine metabolism inhibition in tumor cells improves antitumor T lymphocyte activity in triple-negative breast cancer.

Authors:  Deanna N Edwards; Verra M Ngwa; Ariel L Raybuck; Shan Wang; Yoonha Hwang; Laura C Kim; Sung Hoon Cho; Yeeun Paik; Qingfei Wang; Siyuan Zhang; H Charles Manning; Jeffrey C Rathmell; Rebecca S Cook; Mark R Boothby; Jin Chen
Journal:  J Clin Invest       Date:  2021-02-15       Impact factor: 14.808

Review 3.  Nutrient metabolism and cancer in the in vivo context: a metabolic game of give and take.

Authors:  Patricia Altea-Manzano; Alejandro M Cuadros; Lindsay A Broadfield; Sarah-Maria Fendt
Journal:  EMBO Rep       Date:  2020-09-23       Impact factor: 8.807

Review 4.  Targeting Metabolic Reprogramming in Acute Myeloid Leukemia.

Authors:  Isabel Castro; Belém Sampaio-Marques; Paula Ludovico
Journal:  Cells       Date:  2019-08-24       Impact factor: 6.600

Review 5.  EMT Factors and Metabolic Pathways in Cancer.

Authors:  Ilias Georgakopoulos-Soares; Dionysios V Chartoumpekis; Venetsana Kyriazopoulou; Apostolos Zaravinos
Journal:  Front Oncol       Date:  2020-04-07       Impact factor: 6.244

Review 6.  Molecular and Metabolic Reprogramming: Pulling the Strings Toward Tumor Metastasis.

Authors:  Ana Hipólito; Filipa Martins; Cindy Mendes; Filipa Lopes-Coelho; Jacinta Serpa
Journal:  Front Oncol       Date:  2021-06-03       Impact factor: 6.244

Review 7.  Structural and biophysical aspects of l-asparaginases: a growing family with amazing diversity.

Authors:  Joanna I Loch; Mariusz Jaskolski
Journal:  IUCrJ       Date:  2021-06-30       Impact factor: 4.769

Review 8.  Engineering strategies to capture the biological and biophysical tumor microenvironment in vitro.

Authors:  Matthew L Tan; Lu Ling; Claudia Fischbach
Journal:  Adv Drug Deliv Rev       Date:  2021-06-28       Impact factor: 17.873

Review 9.  Non-Coding RNAs Operate in the Crosstalk Between Cancer Metabolic Reprogramming and Metastasis.

Authors:  Ziyi Li; Xueying Sun
Journal:  Front Oncol       Date:  2020-05-29       Impact factor: 6.244

Review 10.  Development of L-Asparaginase Biobetters: Current Research Status and Review of the Desirable Quality Profiles.

Authors:  Larissa Pereira Brumano; Francisco Vitor Santos da Silva; Tales Alexandre Costa-Silva; Alexsandra Conceição Apolinário; João Henrique Picado Madalena Santos; Eduardo Krebs Kleingesinds; Gisele Monteiro; Carlota de Oliveira Rangel-Yagui; Brahim Benyahia; Adalberto Pessoa Junior
Journal:  Front Bioeng Biotechnol       Date:  2019-01-10
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