Literature DB >> 29712056

"Total Synthesis" Supramolecular Style: Design and Hydrogen-Bond-Directed Assembly of Ternary Supermolecules.

Christer B Aakeröy1, Alicia M Beatty2, Brian A Helfrich1.   

Abstract

Getting the right balance between intermolecular interactions is crucial for the synthesis of supermolecules in a preconceived manner. The three-component supermolecule in the ternary cocrystal of 3,5-dinitrobenzoic acid, isonicotinamide, and 4-(dimethylamino)benzoic acid (1:1:1) assembles through a "primary" (between the stronger acid and pyridine) and a "secondary" hydrogen-bonding interaction (between the weaker acid and amide).
© 2001 WILEY-VCH Verlag GmbH, Weinheim, Fed. Rep. of Germany.

Entities:  

Keywords:  cocrystals; crystal engineering; hydrogen bonds; molecular recognition; supramolecular chemistry

Year:  2001        PMID： 29712056     DOI： 10.1002/1521-3773(20010903)40:17<3240::AID-ANIE3240>3.0.CO;2-X

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  7 in total

Review 1.  Engineering Cocrystals of PoorlyWater-Soluble Drugs to Enhance Dissolution in Aqueous Medium.

Authors:  Indumathi Sathisaran; Sameer Vishvanath Dalvi
Journal:  Pharmaceutics       Date:  2018-07-31       Impact factor: 6.321

2.  trans-Diaqua-bis-[5-(pyridine-3-carboxamido)-tetra-zolido-κ(2)O,N(1)]zinc dihydrate.

Authors:  Fang Li; Xiang-Ping Ou; Chang-Cang Huang
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2012-04-21

3.  Vibrational Spectroscopic Investigation into Novel Ternary Eutectic Formed between Pyrazinamide, Fumaric Acid, and Isoniazid.

Authors:  Ziming Zhang; Qiqi Wang; Jiadan Xue; Yong Du; Jianjun Liu; Zhi Hong
Journal:  ACS Omega       Date:  2020-07-06

4.  Usage of Quantum Chemical Methods to Understand the Formation of Concomitant Polymorphs of Acetyl 2-(N-(2-Fluorophenyl)imino)coumarin-3-carboxamide.

Authors:  Svitlana V Shishkina; Vyacheslav N Baumer; Sergiy M Kovalenko; Pavel V Trostianko; Natalya D Bunyatyan
Journal:  ACS Omega       Date:  2021-01-25

5.  Mechanistic In Situ and Ex Situ Studies of Phase Transformations in Molecular Co-Crystals.

Authors:  Alexander E Clout; Asma B M Buanz; Yuying Pang; Wing-Mei Tsui; Dongpeng Yan; Gary Parkinson; Timothy J Prior; Dejan-Krešimir Bučar; Simon Gaisford; Gareth R Williams
Journal:  Chemistry       Date:  2020-10-07       Impact factor: 5.236

6.  Differences in Coformer Interactions of the 2,4-Diaminopyrimidines Pyrimethamine and Trimethoprim.

Authors:  Lamis Alaa Eldin Refat; Ciaran O'Malley; John M Simmie; Patrick McArdle; Andrea Erxleben
Journal:  Cryst Growth Des       Date:  2022-04-08       Impact factor: 4.010

7.  Improving Dissolution and Cytotoxicity by Forming Multidrug Crystals.

Authors:  Xufei Bian; Lan Jiang; Jing Zhou; Xiaoshu Guan; Jingyu Wang; Peng Xiang; Junyi Pan; Xiangnan Hu
Journal:  Molecules       Date:  2020-03-16       Impact factor: 4.411
  7 in total

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