Literature DB >> 29711729

Synthesis and Biological Evaluation of a Cyclo-β-tetrapeptide as a Somatostatin Analogue.

Karl Gademann1, Martin Ernst1, Daniel Hoyer2, Dieter Seebach1.   

Abstract

Short β-peptides can mimic natural peptide hormones, as has been shown with a cyclo-β-tetrapeptide (1) that displays micromolar affinity to human somatostatin receptors. β-Peptides are thus a promising new class of peptidomimetics with potential high bioavailability due to their excellent resistance against proteases. © 1999 WILEY-VCH Verlag GmbH, Weinheim, Fed. Rep. of Germany.

Entities:  

Keywords:  Hormones; Peptides; Peptidomimetics; Somatostatin

Year:  1999        PMID： 29711729     DOI： 10.1002/(SICI)1521-3773(19990503)38:9<1223::AID-ANIE1223>3.0.CO;2-A

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  9 in total

1.  De Novo Left-Handed Synthetic Peptidomimetic Foldamers.

Authors:  Fengyu She; Peng Teng; Alfredo Peguero-Tejada; Minghui Wang; Ning Ma; Timothy Odom; Mi Zhou; Erald Gjonaj; Lukasz Wojtas; Arjan van der Vaart; Jianfeng Cai
Journal:  Angew Chem Int Ed Engl       Date:  2018-07-03       Impact factor: 15.336

2.  Protein prosthesis: β-peptides as reverse-turn surrogates.

Authors:  Ulrich Arnold; Bayard R Huck; Samuel H Gellman; Ronald T Raines
Journal:  Protein Sci       Date:  2013-01-17       Impact factor: 6.725

3.  β-Aminopeptidases: Insight into Enzymes without a Known Natural Substrate.

Authors:  Marietta John-White; James Gardiner; Priscilla Johanesen; Dena Lyras; Geoffrey Dumsday
Journal:  Appl Environ Microbiol       Date:  2019-07-18       Impact factor: 4.792

4.  Crystal structure of a β-aminopeptidase from an Australian Burkholderia sp.

Authors:  Marietta John-White; Geoff J Dumsday; Priscilla Johanesen; Dena Lyras; Nyssa Drinkwater; Sheena McGowan
Journal:  Acta Crystallogr F Struct Biol Commun       Date:  2017-06-17       Impact factor: 1.056

5.  In Vitro Selection of Macrocyclic α/β3-Peptides against Human EGFR.

Authors:  Risa Wakabayashi; Marina Kawai; Takayuki Katoh; Hiroaki Suga
Journal:  J Am Chem Soc       Date:  2022-09-29       Impact factor: 16.383

6.  Dewar Heterocycles as Versatile Monomers for Ring-Opening Metathesis Polymerization.

Authors:  Sepand K Nistanaki; Hosea M Nelson
Journal:  ACS Macro Lett       Date:  2020-05-01       Impact factor: 6.903

7.  Comparison of design strategies for promotion of beta-peptide 14-helix stability in water.

Authors:  Esther Vaz; William C Pomerantz; Matthias Geyer; Samuel H Gellman; Luc Brunsveld
Journal:  Chembiochem       Date:  2008-09-22       Impact factor: 3.164

8.  Structural Optimization of Foldamer-Dendrimer Conjugates as Multivalent Agents against the Toxic Effects of Amyloid Beta Oligomers.

Authors:  Éva Bartus; Gábor Olajos; Ildikó Schuster; Zsolt Bozsó; Mária A Deli; Szilvia Veszelka; Fruzsina R Walter; Zsolt Datki; Zsolt Szakonyi; Tamás A Martinek; Livia Fülöp
Journal:  Molecules       Date:  2018-10-02       Impact factor: 4.411

9.  α-Helix-Mimicking Sulfono-γ-AApeptide Inhibitors for p53-MDM2/MDMX Protein-Protein Interactions.

Authors:  Peng Sang; Yan Shi; Junhao Lu; Lihong Chen; Leixiang Yang; Wade Borcherds; Sami Abdulkadir; Qi Li; Gary Daughdrill; Jiandong Chen; Jianfeng Cai
Journal:  J Med Chem       Date:  2020-02-03       Impact factor: 7.446
  9 in total

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