Literature DB >> 29711488

Protein Folding: A Perspective from Theory and Experiment.

Christopher M Dobson1, Andrej Šali2, Martin Karplus3.   

Abstract

The mechanism of protein folding (represented schematically below) is one of the most fascinating problems in the field of chemical reactions. This review presents the progess made recently in understanding key elements of this reaction and describes a solution to the often quoted Levinthal Paradox. © 1998 WILEY-VCH Verlag GmbH, Weinheim, Fed. Rep. of Germany.

Keywords:  Kinetics; Molecular dynamics; Protein folding; Proteins; Structure elucidation

Year:  1998        PMID： 29711488     DOI： 10.1002/(SICI)1521-3773(19980420)37:7<868::AID-ANIE868>3.0.CO;2-H

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  66 in total

1.  Non-Arrhenius kinetics for the loop closure of a DNA hairpin.

Authors:  M I Wallace; L Ying; S Balasubramanian; D Klenerman
Journal:  Proc Natl Acad Sci U S A       Date:  2001-04-24       Impact factor: 11.205

2.  A simple model for calculating the kinetics of protein folding from three-dimensional structures.

Authors:  V Muñoz; W A Eaton
Journal:  Proc Natl Acad Sci U S A       Date:  1999-09-28       Impact factor: 11.205

Review 3.  Searching for "downhill scenarios" in protein folding.

Authors:  W A Eaton
Journal:  Proc Natl Acad Sci U S A       Date:  1999-05-25       Impact factor: 11.205

4.  Meeting halfway on the bridge between protein folding theory and experiment.

Authors:  Vijay S Pande
Journal:  Proc Natl Acad Sci U S A       Date:  2003-03-25       Impact factor: 11.205

5.  What can one learn from experiments about the elusive transition state?

Authors:  Iksoo Chang; Marek Cieplak; Jayanth R Banavar; Amos Maritan
Journal:  Protein Sci       Date:  2004-08-04       Impact factor: 6.725

6.  Three-body interactions improve the prediction of rate and mechanism in protein folding models.

Authors:  M R Ejtehadi; S P Avall; S S Plotkin
Journal:  Proc Natl Acad Sci U S A       Date:  2004-10-06       Impact factor: 11.205

7.  Association thermodynamics and conformational stability of beta-sheet amyloid beta(17-42) oligomers: effects of E22Q (Dutch) mutation and charge neutralization.

Authors:  Nikolay Blinov; Lyudmyla Dorosh; David Wishart; Andriy Kovalenko
Journal:  Biophys J       Date:  2010-01-20       Impact factor: 4.033

8.  Conformational changes during the nanosecond-to-millisecond unfolding of ubiquitin.

Authors:  Hoi Sung Chung; Munira Khalil; Adam W Smith; Ziad Ganim; Andrei Tokmakoff
Journal:  Proc Natl Acad Sci U S A       Date:  2005-01-03       Impact factor: 11.205

9.  Molecular mechanism for stabilizing a short helical peptide studied by generalized-ensemble simulations with explicit solvent.

Authors:  Yuji Sugita; Yuko Okamoto
Journal:  Biophys J       Date:  2005-03-04       Impact factor: 4.033

10.  A critical assessment of the topomer search model of protein folding using a continuum explicit-chain model with extensive conformational sampling.

Authors:  Stefan Wallin; Hue Sun Chan
Journal:  Protein Sci       Date:  2005-06       Impact factor: 6.725
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