Literature DB >> 29711433

A New Heterocyclic Multicomponent Reaction For the Combinatorial Synthesis of Fused 3-Aminoimidazoles.

Hugues Bienaymé1, Kamel Bouzid1.   

Abstract

When general and reliable, multicomponent reactions are among the most powerful tools in modern drug discovery. The principle of chemical ligation of reactive partners (see reaction scheme) has been employed to find a new, highly efficient synthesis of fused 3-aminoimidazoles. © 1998 WILEY-VCH Verlag GmbH, Weinheim, Fed. Rep. of Germany.

Entities:  

Keywords:  Combinatorial chemistry; Cycloadditions; Heterocycles; Multicomponent reactions

Year:  1998        PMID： 29711433     DOI： 10.1002/(SICI)1521-3773(19980904)37:16<2234::AID-ANIE2234>3.0.CO;2-R

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  25 in total

1.  Microwave-assisted synthesis of a 3-aminoimidazo[1,2-a]-pyridine/pyrazine library by fluorous multicomponent reactions and subsequent cross-coupling reactions.

Authors:  Yimin Lu; Wei Zhang
Journal:  QSAR Comb Sci       Date:  2004

2.  Isocyanide-Based Multicomponent Reactions of Free Phenylboronic Acids.

Authors:  Constantinos G Neochoritis; Tryfon Zarganes-Tzitzikas; Michaela Novotná; Tatiana Mitríková; Zefeng Wang; Katarzyna Kurpiewska; Justyna Kalinowska-Tłuścik; Alexander Dömling
Journal:  Eur J Chem       Date:  2019-08-15

Review 3.  Recent advances on the transition-metal-catalyzed synthesis of imidazopyridines: an updated coverage.

Authors:  Gagandeep Kour Reen; Ashok Kumar; Pratibha Sharma
Journal:  Beilstein J Org Chem       Date:  2019-07-19       Impact factor: 2.883

Review 4.  Recent Applications of the Multicomponent Synthesis for Bioactive Pyrazole Derivatives.

Authors:  Diana Becerra; Rodrigo Abonia; Juan-Carlos Castillo
Journal:  Molecules       Date:  2022-07-23       Impact factor: 4.927

5.  Development of Dimethylisoxazole-Attached Imidazo[1,2-a]pyridines as Potent and Selective CBP/P300 Inhibitors.

Authors:  Alex Muthengi; Virangika K Wimalasena; Hailemichael O Yosief; Melissa J Bikowitz; Logan H Sigua; Tingjian Wang; Deyao Li; Zied Gaieb; Gagan Dhawan; Shuai Liu; Jon Erickson; Rommie E Amaro; Ernst Schönbrunn; Jun Qi; Wei Zhang
Journal:  J Med Chem       Date:  2021-04-19       Impact factor: 7.446

6.  Multicomponent reactions for de novo synthesis of BODIPY probes: in vivo imaging of phagocytic macrophages.

Authors:  Ana Vázquez-Romero; Nicola Kielland; María J Arévalo; Sara Preciado; Richard J Mellanby; Yi Feng; Rodolfo Lavilla; Marc Vendrell
Journal:  J Am Chem Soc       Date:  2013-10-16       Impact factor: 15.419

7.  Nanoscale, automated, high throughput synthesis and screening for the accelerated discovery of protein modifiers.

Authors:  Kai Gao; Shabnam Shaabani; Ruixue Xu; Tryfon Zarganes-Tzitzikas; Li Gao; Maryam Ahmadianmoghaddam; Matthew R Groves; Alexander Dömling
Journal:  RSC Med Chem       Date:  2021-05-05

8.  A novel class of extended pi-conjugated systems: one-pot synthesis of bis-3-aminoimidazo[1,2-a]pyridines, pyrimidines and pyrazines.

Authors:  Ahmad Shaabani; Ebrahim Soleimani; Ali Maleki; Jafar Moghimi-Rad
Journal:  Mol Divers       Date:  2008-12-02       Impact factor: 3.364

9.  Identifying tumor cell growth inhibitors by combinatorial chemistry and zebrafish assays.

Authors:  Jing Xiang; Hongbo Yang; Chao Che; Haixia Zou; Hanshuo Yang; Yuquan Wei; Junmin Quan; Hui Zhang; Zhen Yang; Shuo Lin
Journal:  PLoS One       Date:  2009-02-05       Impact factor: 3.240

10.  Synthesis of α-amino amidines through molecular iodine-catalyzed three-component coupling of isocyanides, aldehydes and amines.

Authors:  Praveen Reddy Adiyala; D Chandrasekhar; Jeevak Sopanrao Kapure; Chada Narsimha Reddy; Ram Awatar Maurya
Journal:  Beilstein J Org Chem       Date:  2014-09-02       Impact factor: 2.883
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