| Literature DB >> 29711227 |
Abstract
A dirty word in synthesis: separation! The normally unavoidable separation at the end of each reaction finds no friends among synthetic chemists and is often regarded as a technical procedure. However, the need to quickly and cheaply produce pure products is driving the development of new separation and purification techniques. Astonishingly, the modern concepts and techniques for coupling synthesis and separation are rooted in workup procedures that are as old as the art of synthesis itself. © 1998 WILEY-VCH Verlag GmbH, Weinheim, Fed. Rep. of Germany.Keywords: Combinatorial chemistry; Fluorous synthesis; Solid-phase synthesis; Synthesis design
Year: 1998 PMID: 29711227 DOI: 10.1002/(SICI)1521-3773(19980518)37:9<1174::AID-ANIE1174>3.0.CO;2-P
Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN: 1433-7851 Impact factor: 15.336