Literature DB >> 29711227

Strategy-Level Separations in Organic Synthesis: From Planning to Practice.

Dennis P Curran1.   

Abstract

A dirty word in synthesis: separation! The normally unavoidable separation at the end of each reaction finds no friends among synthetic chemists and is often regarded as a technical procedure. However, the need to quickly and cheaply produce pure products is driving the development of new separation and purification techniques. Astonishingly, the modern concepts and techniques for coupling synthesis and separation are rooted in workup procedures that are as old as the art of synthesis itself. © 1998 WILEY-VCH Verlag GmbH, Weinheim, Fed. Rep. of Germany.

Keywords:  Combinatorial chemistry; Fluorous synthesis; Solid-phase synthesis; Synthesis design

Year:  1998        PMID: 29711227     DOI: 10.1002/(SICI)1521-3773(19980518)37:9<1174::AID-ANIE1174>3.0.CO;2-P

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN: 1433-7851            Impact factor:   15.336


  7 in total

1.  Microwave-assisted synthesis of a 3-aminoimidazo[1,2-a]-pyridine/pyrazine library by fluorous multicomponent reactions and subsequent cross-coupling reactions.

Authors:  Yimin Lu; Wei Zhang
Journal:  QSAR Comb Sci       Date:  2004

2.  Creating biocompatible oil-water interfaces without synthesis: direct interactions between primary amines and carboxylated perfluorocarbon surfactants.

Authors:  Cheryl J DeJournette; Joonyul Kim; Haley Medlen; Xiangpeng Li; Luke J Vincent; Christopher J Easley
Journal:  Anal Chem       Date:  2013-10-23       Impact factor: 6.986

3.  Fluorous parallel synthesis of a hydantoin/thiohydantoin library.

Authors:  Yimin Lu; Wei Zhang
Journal:  Mol Divers       Date:  2005       Impact factor: 2.943

4.  Asymmetric solution-phase mixture aldol reaction using oligomeric ethylene glycol tagged chiral oxazolidinones.

Authors:  Serhan Turkyilmaz; Craig S Wilcox
Journal:  Tetrahedron Lett       Date:  2017-04-06       Impact factor: 2.415

5.  Base-Induced Instability of Fluorotelomer Alcohols.

Authors:  William B Tucker; Sandro Mecozzi
Journal:  J Fluor Chem       Date:  2013-12-01       Impact factor: 2.050

6.  Ionic Fluorogels for Remediation of Per- and Polyfluorinated Alkyl Substances from Water.

Authors:  Elango Kumarasamy; Irene M Manning; Leonard B Collins; Orlando Coronell; Frank A Leibfarth
Journal:  ACS Cent Sci       Date:  2020-02-27       Impact factor: 14.553

Review 7.  Enhanced single-cell encapsulation in microfluidic devices: From droplet generation to single-cell analysis.

Authors:  Si Da Ling; Yuhao Geng; An Chen; Yanan Du; Jianhong Xu
Journal:  Biomicrofluidics       Date:  2020-12-22       Impact factor: 2.800

  7 in total

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