Chao Li1,2, Ralph B D'Agostino3, Dana Dabelea4, Angela D Liese1, Elizabeth J Mayer-Davis5, Russell Pate1, Anwar T Merchant1. 1. Department of Epidemiology and Biostatistics, University of South Carolina, Columbia, South Carolina. 2. Department of Health Science and Research, Medical University of South Carolina, Charleston, South Carolina. 3. School of Medicine, Wake Forest University, Winston-Salem, North Carolina. 4. Department of Epidemiology, University of Colorado at Denver, Denver, Colorado. 5. Department of Nutrition, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Abstract
BACKGROUND: Few studies have evaluated the prospective association of eating frequency with HbA1c levels and cardiovascular disease risk markers among youth with diabetes. OBJECTIVE: To examine the 5-year longitudinal association of eating frequency with HbA1c and serum lipid levels among youth with type 1 diabetes (T1D) or type 2 diabetes (T2D). METHODS: One-thousand and forty-nine youth (≥10-year old) with incident T1D (n = 821) or T2D (n = 228) who participated in the SEARCH for Diabetes in Youth study were included. Eating frequency (≤3, 4-5, or 6-10 times/d) measured at baseline and follow-up visits was related to HbA1c and serum lipid levels measured repeatedly over 5 years. RESULTS: Increased eating frequency was associated with larger increases in HbA1c among youth T1D. For example, for youth with T1D who ate ≤3 times/d at the outset and ate 6-10 times/d 5 years later, the longitudinal model predicted greater absolute increases in HbA1c (2.77%); whereas for youth with T1D who ate 6-10 times/d at the outset and ate ≤3 times/d 5 years later, the model predicted lesser absolute increases in HbA1c (1.33%). Eating frequency was not associated with changes in serum lipid levels among youth with T1D or T2D. CONCLUSIONS: Youth with T1D who increased their eating frequency vs those who decreased it had larger increases in HbA1c over 5 years.
BACKGROUND: Few studies have evaluated the prospective association of eating frequency with HbA1c levels and cardiovascular disease risk markers among youth with diabetes. OBJECTIVE: To examine the 5-year longitudinal association of eating frequency with HbA1c and serum lipid levels among youth with type 1 diabetes (T1D) or type 2 diabetes (T2D). METHODS: One-thousand and forty-nine youth (≥10-year old) with incident T1D (n = 821) or T2D (n = 228) who participated in the SEARCH for Diabetes in Youth study were included. Eating frequency (≤3, 4-5, or 6-10 times/d) measured at baseline and follow-up visits was related to HbA1c and serum lipid levels measured repeatedly over 5 years. RESULTS: Increased eating frequency was associated with larger increases in HbA1c among youth T1D. For example, for youth with T1D who ate ≤3 times/d at the outset and ate 6-10 times/d 5 years later, the longitudinal model predicted greater absolute increases in HbA1c (2.77%); whereas for youth with T1D who ate 6-10 times/d at the outset and ate ≤3 times/d 5 years later, the model predicted lesser absolute increases in HbA1c (1.33%). Eating frequency was not associated with changes in serum lipid levels among youth with T1D or T2D. CONCLUSIONS: Youth with T1D who increased their eating frequency vs those who decreased it had larger increases in HbA1c over 5 years.
Authors: M M Windhauser; D B Ernst; N M Karanja; S W Crawford; S E Redican; J F Swain; J M Karimbakas; C M Champagne; K P Hoben; M A Evans Journal: J Am Diet Assoc Date: 1999-08
Authors: Angela D Liese; Jamie L Crandell; Janet A Tooze; Mary T Fangman; Sarah C Couch; Anwar T Merchant; Ronny A Bell; Elizabeth J Mayer-Davis Journal: Public Health Nutr Date: 2014-03-28 Impact factor: 4.022
Authors: David M Maahs; Dana Dabelea; Ralph B D'Agostino; Jeannette S Andrews; Amy S Shah; Nancy Crimmins; Elizabeth J Mayer-Davis; Santica Marcovina; Giuseppina Imperatore; R Paul Wadwa; Steven R Daniels; Kristi Reynolds; Richard F Hamman; Lawrence M Dolan Journal: J Pediatr Date: 2012-07-11 Impact factor: 4.406
Authors: Dana Dabelea; Katherine A Sauder; Elizabeth T Jensen; Amy K Mottl; Alyssa Huang; Catherine Pihoker; Richard F Hamman; Jean Lawrence; Lawrence M Dolan; Ralph D' Agostino; Lynne Wagenknecht; Elizabeth J Mayer-Davis; Santica M Marcovina Journal: Ann N Y Acad Sci Date: 2021-02-05 Impact factor: 6.499