Yasushi Shintani1, Seiki Hasegawa2, Teruhisa Takuwa2, Keisuke Aoe3, Katsuya Kato4, Nobukazu Fujimoto5, Yasuhiro Hida6, Masahiro Morise7, Yasumitsu Moriya8, Takao Morohoshi9, Meinoshin Okumura1, Ichiro Yoshino10. 1. Department of General Thoracic Surgery, Osaka University Graduate School of Medicine, Osaka, Japan. 2. Department of Thoracic Surgery, Hyogo College of Medicine, Hyogo, Japan. 3. Department of Medical Oncology, National Hospital Organization Yamaguchi-Ube Medical Center, Yamaguchi, Japan. 4. Department of Diagnostic Radiology 2, Kawasaki Medical School, Okayama, Japan. 5. Department of Medical Oncology, Okayama Rosai Hospital, Okayama, Japan. 6. Department of Cardiovascular and Thoracic Surgery, Hokkaido University Graduate School of Medicine, Hokkaido, Japan. 7. Department of Respiratory Medicine, Nagoya University Graduate School of Medicine, Aichi, Japan. 8. Division of General Thoracic Surgery, Chiba Rosai Hospital, Chiba, Japan. 9. Division of General Thoracic Surgery, Yokosuka-Kyosai Hospital, Kanagawa, Japan. 10. Department of General Thoracic Surgery, Chiba University Graduate School of Medicine, Chiba, Japan.
Abstract
BACKGROUND: The International Association for the Study of Lung Cancer, in collaboration with members of the International Mesothelioma Interest Group (IMIG), developed a large international database and TNM-based system to study malignant pleural mesothelioma (MPM). However, this database has some limitations since it was a retrospective study and it was based predominantly on surgical cases. The Japanese Joint Committee of Lung Cancer Registry (JJCLCR) employs a project of prospective registry database of patients in Japan with MPM in order to clarify MPM's epidemiology, current management practices, and prognosis and also to investigate the potential capabilities to target the best patients for therapy. METHODS: Tumor stage is described using the 7th and 8th versions of IMIG staging system. This prospective cohort study has been conducted from April 1, 2017 to March 31, 2019. DISCUSSION: We will analyze the data in this registry to determine the most recent outcomes and trends related to MPM treatment in Japan. The present prospective study is expected to validate the 8th version of IMIG staging system, and to investigate whether tumor thickness is a reliable T-descriptor. TRIAL REGISTRATION: ClinicalTrials.gov Identifier: UMIN 000024664.
BACKGROUND: The International Association for the Study of Lung Cancer, in collaboration with members of the International Mesothelioma Interest Group (IMIG), developed a large international database and TNM-based system to study malignant pleural mesothelioma (MPM). However, this database has some limitations since it was a retrospective study and it was based predominantly on surgical cases. The Japanese Joint Committee of Lung Cancer Registry (JJCLCR) employs a project of prospective registry database of patients in Japan with MPM in order to clarify MPM's epidemiology, current management practices, and prognosis and also to investigate the potential capabilities to target the best patients for therapy. METHODS: Tumor stage is described using the 7th and 8th versions of IMIG staging system. This prospective cohort study has been conducted from April 1, 2017 to March 31, 2019. DISCUSSION: We will analyze the data in this registry to determine the most recent outcomes and trends related to MPM treatment in Japan. The present prospective study is expected to validate the 8th version of IMIG staging system, and to investigate whether tumor thickness is a reliable T-descriptor. TRIAL REGISTRATION: ClinicalTrials.gov Identifier: UMIN 000024664.
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