| Literature DB >> 29698756 |
Ali Rıza Kosker1, Fatih Özogul2, Mustafa Durmus3, Yılmaz Ucar3, Deniz Ayas4, Vida Šimat5, Yeşim Özogul3.
Abstract
The differences of tetrodotoxin (TTX) levels in various parts of pufferfish (Torquigener flavimaculosus) were examined in conjunction with the seasonal and sexual variations. The TTX levels in gonads, liver, intestines, skin and muscle tissue were determined using the Q-TOF LC/MS. Instrumental analysis revealed that all examined tissues from T. flavimaculosus contained high TTX concentrations. TTX levels in the gonads, liver, intestines, skin and muscle tissue of pufferfish were within the range of 5.03-100.71, 7.04-106.80, 12.59-86.30, 33.95-139.88 and 15.88-86.07 (μg/g), respectively. It was determined that in all seasons, except for summer, female individuals had higher TTX levels than males. Among all seasons, the highest level of TTX was found in winter and the lowest in autumn. Consequently, T. flavimaculosus is a highly toxic pufferfish that is dangerous for human consumption and should not be consumed under any circumstances.Entities:
Keywords: North-eastern mediterranean; Q-TOF LC/MS; Tetrodotoxin; Torquigener flavimaculosus; Yellow spotted pufferfish
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Year: 2018 PMID： 29698756 DOI： 10.1016/j.toxicon.2018.04.018
Source DB: PubMed Journal: Toxicon ISSN： 0041-0101 Impact factor: 3.033