Guangbo Qu1, Lingling Wang1, Xue Tang1, Wei Wu1, Yehuan Sun1,2. 1. 1 Department of Epidemiology and Health Statistics, School of Public Health, Anhui Medical University , Hefei, Anhui, China . 2. 2 Center for Evidence-Based Practice, Anhui Medical University , Hefei, China .
Abstract
OBJECTIVES: Recently, an increasing number of studies have implied that breastfeeding has a protective effect on maternal hypertension, but it remains controversial. The aim of this study is to evaluate the effect of breastfeeding on maternal hypertension through meta-analysis. MATERIALS AND METHODS: Eligible studies were searched and identified in various databases. Meta-analysis was conducted to assess the association between the duration of breastfeeding and maternal hypertension. RESULTS: Seven eligible studies that contained 444,759 participants were included in our study. Meta-analysis of these seven studies showed a significant protective effect of breastfeeding on maternal hypertension. Specifically, pooled odds ratios (ORs) of hypertension for >0-6, >6-12, and >12 months of breastfeeding were 0.92 (95% confidence interval [CI]: 0.88-0.96, I2 = 67.5%), 0.89 (95% CI: 0.86-0.92, I2 = 0), and 0.88 (95% CI: 0.84-0.93, I2 = 43.9%), respectively, compared with nonbreastfeeding mothers, and the pooled OR of hypertension was 0.93 (95% CI: 0.91-0.95, I2 = 40.8%) for women who breastfed compared with women who had not. Furthermore, the pooled hazard ratio of hypertension was 1.34 (95% CI: 1.17-1.52, I2 = 58.7%) for women who did not breastfeed compared with women who breastfed for more than 12 months for their first child. CONCLUSION: Different durations of breastfeeding have different protective effects against the development of maternal hypertension, and breastfeeding for >12 months has a better effect than <12 months.
OBJECTIVES: Recently, an increasing number of studies have implied that breastfeeding has a protective effect on maternal hypertension, but it remains controversial. The aim of this study is to evaluate the effect of breastfeeding on maternal hypertension through meta-analysis. MATERIALS AND METHODS: Eligible studies were searched and identified in various databases. Meta-analysis was conducted to assess the association between the duration of breastfeeding and maternal hypertension. RESULTS: Seven eligible studies that contained 444,759 participants were included in our study. Meta-analysis of these seven studies showed a significant protective effect of breastfeeding on maternal hypertension. Specifically, pooled odds ratios (ORs) of hypertension for >0-6, >6-12, and >12 months of breastfeeding were 0.92 (95% confidence interval [CI]: 0.88-0.96, I2 = 67.5%), 0.89 (95% CI: 0.86-0.92, I2 = 0), and 0.88 (95% CI: 0.84-0.93, I2 = 43.9%), respectively, compared with nonbreastfeeding mothers, and the pooled OR of hypertension was 0.93 (95% CI: 0.91-0.95, I2 = 40.8%) for women who breastfed compared with women who had not. Furthermore, the pooled hazard ratio of hypertension was 1.34 (95% CI: 1.17-1.52, I2 = 58.7%) for women who did not breastfeed compared with women who breastfed for more than 12 months for their first child. CONCLUSION: Different durations of breastfeeding have different protective effects against the development of maternal hypertension, and breastfeeding for >12 months has a better effect than <12 months.
Authors: Gina M Richardson; Emily Mitchell; Kalera Stratton; Laura R Kair; Lynn M Marshall Journal: Breastfeed Med Date: 2022-08-12 Impact factor: 2.335
Authors: Lena Tschiderer; Lisa Seekircher; Setor K Kunutsor; Sanne A E Peters; Linda M O'Keeffe; Peter Willeit Journal: J Am Heart Assoc Date: 2022-01-11 Impact factor: 6.106
Authors: Pandora L Wander; Stefanie N Hinkle; Daniel A Enquobahrie; Jing Wu; Sylvia H Ley; Louise G Grunnet; Jorge E Chavarro; Mengying Li; Anne A Bjerregaard; Aiyi Liu; Peter Damm; Seth Sherman; Shristi Rawal; Yeyi Zhu; Liwei Chen; James L Mills; Frank B Hu; Allan Vaag; Sjurdur F Olsen; Cuilin Zhang Journal: Nutrients Date: 2022-02-03 Impact factor: 6.706