Motoaki Yasukawa1, Noriyoshi Sawabata2, Takeshi Kawaguchi2, Norikazu Kawai2, Shigeki Taniguchi2. 1. Department of Thoracic and Cardiovascular Surgery, Nara Medical University School of Medicine, Nara, Japan myasukawa@naramed-u.ac.jp. 2. Department of Thoracic and Cardiovascular Surgery, Nara Medical University School of Medicine, Nara, Japan.
Abstract
BACKGROUND/AIM: Lung biopsies might cause metastasis and/or dissemination. The aim of this study was to review our institutional experience and analyze the outcomes of resection for non-small cell lung cancer (NSCLC), in patients who had received preoperative transbronchial biopsy using fiberoptic bronchoscopy with fluoroscopic imaging (BFS). PATIENTS AND METHODS: The medical records of consecutive patients between 2010 and 2015 were retrospectively reviewed. Patients were divided into two groups (BFS and Non-BFS). Overall survival (OS) curves and recurrence-free survival (RFS) curves were plotted using the Kaplan-Meier method. Cox regression analyses were used to evaluate the hazard ratio (HR) with the endpoint OS or RFS. RESULTS: We studied the medical records of 531 patients. The 5-year OS rate was 91.8% and 79.8%, in the BFS group and in the Non-BFS group, respectively (p<0.001). BFS was an independent factor associated with RFS HR=2.164 (95%CI=1.399-2.346). CONCLUSION: Preoperative BFS is a prognostic factor in patients receiving surgery for NSCLC. Copyright
BACKGROUND/AIM: Lung biopsies might cause metastasis and/or dissemination. The aim of this study was to review our institutional experience and analyze the outcomes of resection for non-small cell lung cancer (NSCLC), in patients who had received preoperative transbronchial biopsy using fiberoptic bronchoscopy with fluoroscopic imaging (BFS). PATIENTS AND METHODS: The medical records of consecutive patients between 2010 and 2015 were retrospectively reviewed. Patients were divided into two groups (BFS and Non-BFS). Overall survival (OS) curves and recurrence-free survival (RFS) curves were plotted using the Kaplan-Meier method. Cox regression analyses were used to evaluate the hazard ratio (HR) with the endpoint OS or RFS. RESULTS: We studied the medical records of 531 patients. The 5-year OS rate was 91.8% and 79.8%, in the BFS group and in the Non-BFS group, respectively (p<0.001). BFS was an independent factor associated with RFS HR=2.164 (95%CI=1.399-2.346). CONCLUSION: Preoperative BFS is a prognostic factor in patients receiving surgery for NSCLC. Copyright
Authors: Ramón Rami-Porta; Vanessa Bolejack; John Crowley; David Ball; Jhingook Kim; Gustavo Lyons; Thomas Rice; Kenji Suzuki; Charles F Thomas; William D Travis; Yi-Long Wu Journal: J Thorac Oncol Date: 2015-07 Impact factor: 15.609
Authors: Edward Gitau Mathenge; Cheryl Ann Dean; Derek Clements; Ahmad Vaghar-Kashani; Steffany Photopoulos; Krysta Mila Coyle; Michael Giacomantonio; Benjamin Malueth; Anna Nunokawa; Julie Jordan; John D Lewis; Shashi Ashok Gujar; Paola Marcato; Patrick W K Lee; Carman Anthony Giacomantonio Journal: Neoplasia Date: 2014-11-20 Impact factor: 5.715