Ralf Ohlinger1, Leonie Gieron1, Rico Rutkowski2, Thomas Kohlmann3, Marek Zygmunt1, Julia Unger4. 1. Clinic and Polyclinic for Obstetrics and Gynecology, University Medicine Greifswald, Greifswald, Germany. 2. Department of Oral and Maxillofacial Surgery/Plastic Surgery, University Medicine Greifswald, Greifswald, Germany. 3. Department of Community Medicine, University Greifswald, Greifswald, Germany. 4. Clinic and Polyclinic for Obstetrics and Gynecology, University Medicine Greifswald, Greifswald, Germany jk114735@uni-greifswald.de.
Abstract
BACKGROUND/AIM: Using drains after breast surgery is a preventive, but invasive measure to reduce seroma formation. A polyurethane-based tissue adhesive (TissuGlu®) might facilitate drainage-free wound healing after mastectomy in a non-invasive manner. PATIENTS AND METHODS: Retrospectively, data from 84 patients (42 receiving TissuGlu®, 42 receiving a drainage) who underwent mastectomy, were collected (90 days postoperative follow-up). Study endpoints were defined as the number of fluid-related postoperative clinical interventions, cumulative volume of postoperative wound fluid, duration of hospitalization and postoperative complications. RESULTS: In the entirety of postoperative interventions, no significant difference could be demonstrated (p=0.298). The drainage arm showed significantly less seroma aspirations (p=0.024) and complications (p=0.012). A significantly reduced length of hospitalization (p<0.001) and less cumulative wound secretion volume (p<0.001) appeared in the TissuGlu® group. CONCLUSION: The polyurethane-based tissue adhesive is a less invasive alternative to drain use in mastectomy. Copyright
BACKGROUND/AIM: Using drains after breast surgery is a preventive, but invasive measure to reduce seroma formation. A polyurethane-based tissue adhesive (TissuGlu®) might facilitate drainage-free wound healing after mastectomy in a non-invasive manner. PATIENTS AND METHODS: Retrospectively, data from 84 patients (42 receiving TissuGlu®, 42 receiving a drainage) who underwent mastectomy, were collected (90 days postoperative follow-up). Study endpoints were defined as the number of fluid-related postoperative clinical interventions, cumulative volume of postoperative wound fluid, duration of hospitalization and postoperative complications. RESULTS: In the entirety of postoperative interventions, no significant difference could be demonstrated (p=0.298). The drainage arm showed significantly less seroma aspirations (p=0.024) and complications (p=0.012). A significantly reduced length of hospitalization (p<0.001) and less cumulative wound secretion volume (p<0.001) appeared in the TissuGlu® group. CONCLUSION: The polyurethane-based tissue adhesive is a less invasive alternative to drain use in mastectomy. Copyright
Authors: Thomas W Gilbert; Stephen F Badylak; Eric J Beckman; Dottie M Clower; J Peter Rubin Journal: J Plast Reconstr Aesthet Surg Date: 2012-10-31 Impact factor: 2.740
Authors: Joseph P Hunstad; Joseph Michaels; A Jay Burns; Sheri Slezak; W Grant Stevens; Dottie M Clower; J Peter Rubin Journal: Aesthetic Plast Surg Date: 2015-06-05 Impact factor: 2.326