Literature DB >> 29690940

Clinical Characteristics and Outcomes of Hematologic Malignancy Patients With Positive Clostridium difficile Toxin Immunoassay Versus Polymerase Chain Reaction Test Results.

Matthew Ziegler1, Daniel Landsburg2, David Pegues1, Kevin Alby3, Cheryl Gilmar4, Kristen Bink2, Theresa Gorman2, Amy Moore2, Brittaney Bonhomme5, Jacqueline Omorogbe5, Dana Tango5, Pam Tolomeo5, Jennifer H Han1.   

Abstract

In a cohort of inpatients with hematologic malignancy and positive enzyme immunoassay (EIA) or polymerase chain reaction (PCR) Clostridium difficile tests, we found that clinical characteristics and outcomes were similar between these groups. The method of testing is unlikely to predict infection in this population, and PCR-positive results should be treated with concern.Infect Control Hosp Epidemiol 2018;863-866.

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Year:  2018        PMID： 29690940      PMCID： PMC6031467          DOI： 10.1017/ice.2018.83

Source DB:  PubMed          Journal:  Infect Control Hosp Epidemiol        ISSN： 0899-823X            Impact factor:   3.254


  11 in total

1.  Clostridium difficile rates in asymptomatic and symptomatic hospitalized patients using nucleic acid testing.

Authors:  Cynthia Truong; Lee F Schroeder; Rajiv Gaur; Victoria Emma Anikst; Ikuko Komo; Colleen Watters; Erin McCalley; Carole Kulik; David Pickham; Nancy J Lee; Niaz Banaei
Journal:  Diagn Microbiol Infect Dis       Date:  2017-01-03       Impact factor: 2.803

Review 2.  Guidelines for diagnosis, treatment, and prevention of Clostridium difficile infections.

Authors:  Christina M Surawicz; Lawrence J Brandt; David G Binion; Ashwin N Ananthakrishnan; Scott R Curry; Peter H Gilligan; Lynne V McFarland; Mark Mellow; Brian S Zuckerbraun
Journal:  Am J Gastroenterol       Date:  2013-02-26       Impact factor: 10.864

3.  Significance of a positive Clostridium difficile toxin test after hematopoietic stem cell transplantation.

Authors:  Yu Akahoshi; Shun-Ichi Kimura; Hirofumi Nakano; Naonori Harada; Kazuaki Kameda; Tomotaka Ugai; Hidenori Wada; Ryoko Yamasaki; Yuko Ishihara; Koji Kawamura; Kana Sakamoto; Masahiro Ashizawa; Miki Sato; Kiriko Terasako-Saito; Hideki Nakasone; Misato Kikuchi; Rie Yamazaki; Junya Kanda; Shinichi Kako; Junji Nishida; Yoshinobu Kanda
Journal:  Clin Transplant       Date:  2016-04-21       Impact factor: 2.863

4.  Clostridium difficile colonization and disease in patients undergoing hematopoietic stem cell transplantation.

Authors:  Jackrapong Bruminhent; Zi-Xuan Wang; Carol Hu; John Wagner; Richard Sunday; Brent Bobik; Sarah Hegarty; Scott Keith; Seyfettin Alpdogan; Matthew Carabasi; Joanne Filicko-O'Hara; Neal Flomenberg; Margaret Kasner; Ubaldo Martinez Outschoorn; Mark Weiss; Phyllis Flomenberg
Journal:  Biol Blood Marrow Transplant       Date:  2014-05-02       Impact factor: 5.742

5.  Impact of clinical symptoms on interpretation of diagnostic assays for Clostridium difficile infections.

Authors:  Erik R Dubberke; Zhuolin Han; Linda Bobo; Tiffany Hink; Brenda Lawrence; Susan Copper; Joan Hoppe-Bauer; Carey-Ann D Burnham; William Michael Dunne
Journal:  J Clin Microbiol       Date:  2011-06-22       Impact factor: 5.948

6.  Clostridium difficile infection in allogeneic stem cell transplant recipients is associated with severe graft-versus-host disease and non-relapse mortality.

Authors:  S Chakrabarti; A Lees; S G Jones; D W Milligan
Journal:  Bone Marrow Transplant       Date:  2000-10       Impact factor: 5.483

7.  Chemotherapy-induced diarrhea: pathophysiology, frequency and guideline-based management.

Authors:  Alexander Stein; Wieland Voigt; Karin Jordan
Journal:  Ther Adv Med Oncol       Date:  2010-01       Impact factor: 8.168

8.  Clostridium Difficile Colonization in Hematopoietic Stem Cell Transplant Recipients: A Prospective Study of the Epidemiology and Outcomes Involving Toxigenic and Nontoxigenic Strains.

Authors:  Tania Jain; Christopher Croswell; Varinia Urday-Cornejo; Reda Awali; Jessica Cutright; Hossein Salimnia; Harsha Vardhan Reddy Banavasi; Alyssa Liubakka; Paul Lephart; Teena Chopra; Sanjay G Revankar; Pranatharthi Chandrasekar; George Alangaden
Journal:  Biol Blood Marrow Transplant       Date:  2015-07-26       Impact factor: 5.742

9.  Overdiagnosis of Clostridium difficile Infection in the Molecular Test Era.

Authors:  Christopher R Polage; Clare E Gyorke; Michael A Kennedy; Jhansi L Leslie; David L Chin; Susan Wang; Hien H Nguyen; Bin Huang; Yi-Wei Tang; Lenora W Lee; Kyoungmi Kim; Sandra Taylor; Patrick S Romano; Edward A Panacek; Parker B Goodell; Jay V Solnick; Stuart H Cohen
Journal:  JAMA Intern Med       Date:  2015-11       Impact factor: 21.873

10.  Differences in outcome according to Clostridium difficile testing method: a prospective multicentre diagnostic validation study of C difficile infection.

Authors:  Timothy D Planche; Kerrie A Davies; Pietro G Coen; John M Finney; Irene M Monahan; Kirsti A Morris; Lily O'Connor; Sarah J Oakley; Cassie F Pope; Mike W Wren; Nandini P Shetty; Derrick W Crook; Mark H Wilcox
Journal:  Lancet Infect Dis       Date:  2013-09-03       Impact factor: 25.071
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  6 in total

1.  Guideline implementation is effective at reducing proton pump inhibitor use in hematology-oncology units: A multidisciplinary intervention for reducing Clostridioides difficile risk.

Authors:  Matthew J Ziegler; Craig Freyer; Daniel Landsburg; David Pegues; Warren Bilker; Rebecca Hirsh; Colleen Kucharczuk; Cheryl Gilmar; Theresa Gorman; Melissa Palmer; Christina Harker; Erin Lightheart; Jennifer H Han
Journal:  Infect Control Hosp Epidemiol       Date:  2019-08-30       Impact factor: 3.254

2.  Evaluation of Cycle Threshold, Toxin Concentration, and Clinical Characteristics of Clostridioides difficile Infection in Patients with Discordant Diagnostic Test Results.

Authors:  Megan D Shah; Joan-Miquel Balada-Llasat; Kelci Coe; Erica Reed; Johanna Sandlund; Preeti Pancholi
Journal:  J Clin Microbiol       Date:  2020-04-23       Impact factor: 5.948

3.  Toxin Enzyme Immunoassays Detect Clostridioides difficile Infection With Greater Severity and Higher Recurrence Rates.

Authors:  Alice Y Guh; Kelly M Hatfield; Lisa G Winston; Brittany Martin; Helen Johnston; Geoffrey Brousseau; Monica M Farley; Lucy Wilson; Rebecca Perlmutter; Erin C Phipps; Ghinwa K Dumyati; Deborah Nelson; Trupti Hatwar; Marion A Kainer; Ashley L Paulick; Maria Karlsson; Dale N Gerding; L Clifford McDonald
Journal:  Clin Infect Dis       Date:  2019-10-30       Impact factor: 9.079

4.  Clinical Outcomes of Treated and Untreated C. difficile PCR-Positive/Toxin-Negative Adult Hospitalized Patients: a Quasi-Experimental Noninferiority Study.

Authors:  Catherine A Hogan; Matthew M Hitchcock; Spencer Frost; Kristopher Kapphahn; Marisa Holubar; Lucy S Tompkins; Niaz Banaei
Journal:  J Clin Microbiol       Date:  2022-05-25       Impact factor: 11.677

Review 5.  An Update on Clostridioides difficile Binary Toxin.

Authors:  Adrián Martínez-Meléndez; Flora Cruz-López; Rayo Morfin-Otero; Héctor J Maldonado-Garza; Elvira Garza-González
Journal:  Toxins (Basel)       Date:  2022-04-27       Impact factor: 5.075

6.  Oral Vancomycin Prophylaxis Is Highly Effective in Preventing Clostridium difficile Infection in Allogeneic Hematopoietic Cell Transplant Recipients.

Authors:  Alex Ganetsky; Jennifer H Han; Mitchell E Hughes; Daria V Babushok; Noelle V Frey; Saar I Gill; Elizabeth O Hexner; Alison W Loren; Selina M Luger; James K Mangan; Mary Ellen Martin; Jacqueline Smith; Craig W Freyer; Cheryl Gilmar; Mindy Schuster; Edward A Stadtmauer; David L Porter
Journal:  Clin Infect Dis       Date:  2019-05-30       Impact factor: 9.079
  6 in total

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