Ebru Arhan1,2, Ayşe Serdaroğlu3, Tuğba Hirfanoğlu3, Gökhan Kurt4. 1. Department of Pediatric Neurology, Gazi University School of Medicine, Ankara, Turkey. petekarhan@yahoo.com.tr. 2. Pediatric Neurology Department, Gazi University Faculty of Medicine, 10 th Floor Besevler-, Ankara, Turkey. petekarhan@yahoo.com.tr. 3. Department of Pediatric Neurology, Gazi University School of Medicine, Ankara, Turkey. 4. Department of Neurosurgery, Gazi University School of Medicine, Ankara, Turkey.
Abstract
BACKGROUND: We describe the first child with drug-resistant epilepsy in whom vagus nerve stimulation aggravated seizures and emerged status epilepticus after the increase in vagal nerve stimulation current output. OBJECTIVE: A 13-year-old girl presented with refractory secondary generalized focal epilepsy. Vagal nerve stimulator was implanted because of drug-resistant epilepsy. After the increase of vagal nerve stimulator current output to a relatively high level, the patient experienced seizure aggravation and status epilepticus. CONCLUSION: We conclude that vagus nerve stimulation may induce paradoxical seizures and may lead to status epilepticus, similarly to some antiepileptic drugs.
BACKGROUND: We describe the first child with drug-resistant epilepsy in whom vagus nerve stimulation aggravated seizures and emerged status epilepticus after the increase in vagal nerve stimulation current output. OBJECTIVE: A 13-year-old girl presented with refractory secondary generalized focal epilepsy. Vagal nerve stimulator was implanted because of drug-resistant epilepsy. After the increase of vagal nerve stimulator current output to a relatively high level, the patient experienced seizure aggravation and status epilepticus. CONCLUSION: We conclude that vagus nerve stimulation may induce paradoxical seizures and may lead to status epilepticus, similarly to some antiepileptic drugs.
Authors: Anna Barnes; Roderick Duncan; Jennifer A Chisholm; Kenneth Lindsay; James Patterson; David Wyper Journal: Eur J Nucl Med Mol Imaging Date: 2002-11-29 Impact factor: 9.236