| Literature DB >> 29675321 |
Juan Heredia-Juesas1, Jeffrey E Thatcher2, Yang Lu2, John J Squiers2,3, Darlene King2, Wensheng Fan2, J Michael DiMaio2,3, Jose A Martinez-Lorenzo1.
Abstract
The process of burn debridement is a challenging technique requiring significant skills to identify the regions that need excision and their appropriate excision depths. In order to assist surgeons, a machine learning tool is being developed to provide a quantitative assessment of burn-injured tissue. This paper presents three non-invasive optical imaging techniques capable of distinguishing four kinds of tissue-healthy skin, viable wound bed, shallow burn, and deep burn-during serial burn debridement in a porcine model. All combinations of these three techniques have been studied through a k-fold cross-validation method. In terms of global performance, the combination of all three techniques significantly improves the classification accuracy with respect to just one technique, from 0.42 up to more than 0.76. Furthermore, a non-linear spatial filtering based on the mode of a small neighborhood has been applied as a post-processing technique, in order to improve the performance of the classification. Using this technique, the global accuracy reaches a value close to 0.78 and, for some particular tissues and combination of techniques, the accuracy improves by 13%.Keywords: (100.0100) Image processing; (110.4155) Multiframe image processing; (110.4234) Multispectral and hyperspectral imaging; (170.3880) Medical and biological imaging; (170.6935) Tissue characterization
Year: 2018 PMID: 29675321 PMCID: PMC5905925 DOI: 10.1364/BOE.9.001809
Source DB: PubMed Journal: Biomed Opt Express ISSN: 2156-7085 Impact factor: 3.732