Literature DB >> 29673533

Brain Imaging Using Hyperpolarized 129Xe Magnetic Resonance Imaging.

Simrun Chahal1, Braedan R J Prete1, Alanna Wade1, Francis T Hane2, Mitchell S Albert3.   

Abstract

Hyperpolarized (HP) 129Xe magnetic resonance imaging (MRI) is a novel iteration of traditional MRI that relies on detecting the spins of 1H. Since 129Xe is a gaseous signal source, it can be used for lung imaging. Additionally, 129Xe dissolves in the blood stream and can therefore be detectable in the brain parenchyma and vasculature. In this work, we provide detailed information on the protocols that we have developed to image 129Xe within the brains of both rodents and human subjects.
© 2018 Elsevier Inc. All rights reserved.

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Keywords:  Brain imaging; Brain mapping; Hyperpolarization; Magnetic resonance imaging; Xenon

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Year:  2018        PMID： 29673533     DOI： 10.1016/bs.mie.2018.01.027

Source DB:  PubMed          Journal:  Methods Enzymol        ISSN： 0076-6879            Impact factor:   1.600


  3 in total

Review 1.  Molecular Sensing with Host Systems for Hyperpolarized 129Xe.

Authors:  Jabadurai Jayapaul; Leif Schröder
Journal:  Molecules       Date:  2020-10-11       Impact factor: 4.411

Review 2.  Nanoparticle-Based Contrast Agents for 129Xe HyperCEST NMR and MRI Applications.

Authors:  Jabadurai Jayapaul; Leif Schröder
Journal:  Contrast Media Mol Imaging       Date:  2019-11-22       Impact factor: 3.161

3.  Evaluation of fluorine-19 magnetic resonance imaging of the lungs using octafluorocyclobutane in a rat model.

Authors:  Yurii Shepelytskyi; Tao Li; Vira Grynko; Camryn Newman; Francis T Hane; Mitchell S Albert
Journal:  Magn Reson Med       Date:  2020-08-12       Impact factor: 4.668
  3 in total

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