BACKGROUND: Studies have reported sex differences in the management of patients with acute myocardial infarction (AMI) in the general population. This observational study is designed to evaluate whether sex differences exist in the contemporary management of human immunodeficiency virus (HIV) patients admitted for diagnosis of AMI. HYPOTHESIS: There is no difference in management of HIV patients with AMI. METHODS: Using the National Inpatient Sample database, we identified patients with a primary diagnosis of AMI and a secondary diagnosis of HIV. We described baseline characteristics and outcomes using NIS documentation. Our primary areas of interest were revascularization and mortality. RESULTS: Among 2 977 387 patients presenting from 2010 to 2014 with a primary diagnosis of AMI, 10907 (0.4%) had HIV (mean age, 54.1 ± 9.3 years; n = 2043 [18.9%] female). Females were younger, more likely to be black, and more likely to have hypertension, diabetes, obesity, and anemia. Although neither males nor females were more likely to undergo coronary angiography in multivariate analysis, revascularization was performed less frequently in females than in males (45.4% vs 62.7%; P < 0.01), driven primarily by lower incidence of PCI. In a multivariate model, females were less likely to undergo revascularization (OR: 0.59, 95% CI: 0.45-0.78, P < 0.01), a finding driven solely by PCI (OR: 0.64, 95% CI: 0.49-0.83, P < 0.01). All-cause mortality was similar in both groups. CONCLUSIONS: AMI was more common in males than females with HIV. Females with HIV were more likely to be younger and black and less likely to be revascularized by PCI.
BACKGROUND: Studies have reported sex differences in the management of patients with acute myocardial infarction (AMI) in the general population. This observational study is designed to evaluate whether sex differences exist in the contemporary management of human immunodeficiency virus (HIV) patients admitted for diagnosis of AMI. HYPOTHESIS: There is no difference in management of HIV patients with AMI. METHODS: Using the National Inpatient Sample database, we identified patients with a primary diagnosis of AMI and a secondary diagnosis of HIV. We described baseline characteristics and outcomes using NIS documentation. Our primary areas of interest were revascularization and mortality. RESULTS: Among 2 977 387 patients presenting from 2010 to 2014 with a primary diagnosis of AMI, 10907 (0.4%) had HIV (mean age, 54.1 ± 9.3 years; n = 2043 [18.9%] female). Females were younger, more likely to be black, and more likely to have hypertension, diabetes, obesity, and anemia. Although neither males nor females were more likely to undergo coronary angiography in multivariate analysis, revascularization was performed less frequently in females than in males (45.4% vs 62.7%; P < 0.01), driven primarily by lower incidence of PCI. In a multivariate model, females were less likely to undergo revascularization (OR: 0.59, 95% CI: 0.45-0.78, P < 0.01), a finding driven solely by PCI (OR: 0.64, 95% CI: 0.49-0.83, P < 0.01). All-cause mortality was similar in both groups. CONCLUSIONS: AMI was more common in males than females with HIV. Females with HIV were more likely to be younger and black and less likely to be revascularized by PCI.
Authors: Ayman Elbadawi; Gbolahan O Ogunbayo; Islam Y Elgendy; Odunayo Olorunfemi; Marwan Saad; Le Dung Ha; Erfan Alotaki; Basarat Baig; A S Abuzaid; Hend I Shahin; Abrar Shah; Mohan Rao Journal: Am J Cardiol Date: 2017-06-28 Impact factor: 2.778
Authors: Niels Obel; Henrik F Thomsen; Gitte Kronborg; Carsten S Larsen; Per R Hildebrandt; Henrik T Sørensen; Jan Gerstoft Journal: Clin Infect Dis Date: 2007-05-10 Impact factor: 9.079
Authors: Kate Buchacz; Rose K Baker; Frank J Palella; Lauren Shaw; Pragna Patel; Kenneth A Lichtenstein; Joan S Chmiel; Claudia Vellozzi; Rachel Debes; Keith Henry; E Turner Overton; Timothy J Bush; Ellen Tedaldi; Charles Carpenter; Kenneth H Mayer; John T Brooks Journal: Antivir Ther Date: 2012-10-30
Authors: Gbolahan O Ogunbayo; Katrina Bidwell; Naoki Misumida; Le Dung Ha; Ahmed Abdel-Latif; Claude S Elayi; Susan Smyth; Adrian W Messerli Journal: Clin Cardiol Date: 2018-04-19 Impact factor: 2.882