Literature DB >> 2966760

Linkage between the loci for the Lp(a) lipoprotein (LP) and plasminogen (PLG).

L R Weitkamp1, S A Guttormsen, J S Schultz.   

Abstract

A locus, LP, that determines quantitative variation of Lp(a) lipoprotein phenotypes is linked to the plasminogen (PLG) locus (peak lod score = 12.73). This linkage relationship assigns a locus with alleles that have an affect on risk for coronary artery disease to the long arm of chromosome 6.

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Year:  1988        PMID： 2966760     DOI： 10.1007/bf00291716

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  17 in total

1.  Linkage relationships of Lp and Ag serum lipoproteins with 25 polymorphic markers.

Authors:  K K Namboodiri; R C Elston; R C Go; K Berg; C Hames
Journal:  Hum Genet       Date:  1977-07-26       Impact factor: 4.132

2.  Lp(a) glycoprotein phenotypes. Inheritance and relation to Lp(a)-lipoprotein concentrations in plasma.

Authors:  G Utermann; H J Menzel; H G Kraft; H C Duba; H G Kemmler; C Seitz
Journal:  J Clin Invest       Date:  1987-08       Impact factor: 14.808

3.  cDNA sequence of human apolipoprotein(a) is homologous to plasminogen.

Authors:  J W McLean; J E Tomlinson; W J Kuang; D L Eaton; E Y Chen; G M Fless; A M Scanu; R M Lawn
Journal:  Nature       Date:  1987 Nov 12-18       Impact factor: 49.962

4.  Linkage disequilibrium of plasminogen polymorphisms and assignment of the gene to human chromosome 6q26-6q27.

Authors:  J C Murray; K H Buetow; M Donovan; S Hornung; A G Motulsky; C Disteche; K Dyer; K Swisshelm; J Anderson; E Giblett
Journal:  Am J Hum Genet       Date:  1987-04       Impact factor: 11.025

Review 5.  Genetics of coronary heart disease.

Authors:  K Berg
Journal:  Prog Med Genet       Date:  1983

6.  Partial amino acid sequence of apolipoprotein(a) shows that it is homologous to plasminogen.

Authors:  D L Eaton; G M Fless; W J Kohr; J W McLean; Q T Xu; C G Miller; R M Lawn; A M Scanu
Journal:  Proc Natl Acad Sci U S A       Date:  1987-05       Impact factor: 11.205

7.  Equine marker genes: polymorphism for plasminogen.

Authors:  L R Weitkamp; P Costello-Leary; S A Guttormsen
Journal:  Anim Blood Groups Biochem Genet       Date:  1983

8.  Black-white differences in serum Lp(a) lipoprotein levels.

Authors:  H J Parra; I Luyéyé; C Bouramoué; C Demarquilly; J C Fruchart
Journal:  Clin Chim Acta       Date:  1987-09-15       Impact factor: 3.786

9.  Fat feeding in humans induces lipoproteins of density less than 1.006 that are enriched in apolipoprotein [a] and that cause lipid accumulation in macrophages.

Authors:  T P Bersot; T L Innerarity; R E Pitas; S C Rall; K H Weisgraber; R W Mahley
Journal:  J Clin Invest       Date:  1986-02       Impact factor: 14.808

10.  Free and Apo B-associated Lpa-specific protein in human serum.

Authors:  A Gries; J Nimpf; M Nimpf; H Wurm; G M Kostner
Journal:  Clin Chim Acta       Date:  1987-04-15       Impact factor: 3.786
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  13 in total

1.  The genetic dissection of complex traits in a founder population.

Authors:  C Ober; M Abney; M S McPeek
Journal:  Am J Hum Genet       Date:  2001-10-03       Impact factor: 11.025

Review 2.  Comparative map for mice and humans.

Authors:  J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M R Kosowsky; T H Roderick
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

3.  The gene for the Lp(a)-specific glycoprotein is closely linked to the gene for plasminogen on chromosome 6.

Authors:  G Lindahl; E Gersdorf; H J Menzel; C Duba; H Cleve; S Humphries; G Utermann
Journal:  Hum Genet       Date:  1989-01       Impact factor: 4.132

4.  Molecular basis of apolipoprotein (a) isoform size heterogeneity as revealed by pulsed-field gel electrophoresis.

Authors:  C Lackner; E Boerwinkle; C C Leffert; T Rahmig; H H Hobbs
Journal:  J Clin Invest       Date:  1991-06       Impact factor: 14.808

Review 5.  Comparative map for mice and humans.

Authors:  J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M Kosowsky; T H Roderick
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

6.  Expressed hypervariable polymorphism of apolipoprotein (a).

Authors:  M I Kamboh; R E Ferrell; B A Kottke
Journal:  Am J Hum Genet       Date:  1991-11       Impact factor: 11.025

7.  The apolipoprotein (a) gene: a transcribed hypervariable locus controlling plasma lipoprotein (a) concentration.

Authors:  H G Kraft; S Köchl; H J Menzel; C Sandholzer; G Utermann
Journal:  Hum Genet       Date:  1992-11       Impact factor: 4.132

8.  Apolipoprotein(a) gene accounts for greater than 90% of the variation in plasma lipoprotein(a) concentrations.

Authors:  E Boerwinkle; C C Leffert; J Lin; C Lackner; G Chiesa; H H Hobbs
Journal:  J Clin Invest       Date:  1992-07       Impact factor: 14.808

9.  The apolipoprotein(a) gene resides on human chromosome 6q26-27, in close proximity to the homologous gene for plasminogen.

Authors:  S L Frank; I Klisak; R S Sparkes; T Mohandas; J E Tomlinson; J W McLean; R M Lawn; A J Lusis
Journal:  Hum Genet       Date:  1988-08       Impact factor: 4.132

Review 10.  Lipoprotein(a): new insights into an atherogenic lipoprotein.

Authors:  W Bartens; C Wanner
Journal:  Clin Investig       Date:  1994-08
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