Literature DB >> 29666075

Rogue one: a story of tophaceous gout in the spine.

Karthik Dwarki1,2, Andy Dothard2, Bryan Abadie2, Matthew C Miles2.   

Abstract

A 26-year-old man with history of extensive tophaceous gout presented to the referring facility with decreased bilateral lower extremity sensation and motor function that began acutely 1 week prior to admission and had progressed to urinary incontinence. The patient was admitted to the intensive care unit due to concern for sepsis secondary to epidural abscess. The patient was started on empiric vancomycin and cefepime. Neurosurgery did not recommend acute neurosurgical intervention given the lack of a compressive lesion. Aspiration of the paraspinal collection by interventional radiology subsequently showed crystals consistent with tophaceous gout. Given the high initial suspicion for gout and results of the paraspinal aspiration, the patient was started on prolonged steroid taper as well as allopurinol and colchicine. The patient eventually had partial neurological recovery with discharge to an inpatient rehabilitation facility for further physical therapy rehabilitation. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Entities:  

Keywords:  medical education; medical management; neuroimaging; rheumatology; spinal cord

Mesh:

Substances:

Year:  2018        PMID: 29666075      PMCID: PMC5905811          DOI: 10.1136/bcr-2017-221163

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  21 in total

Review 1.  Tophaceous Gout of the Lumbar Spine: Case Report and Review of the Literature.

Authors:  Andrey Volkov; David L Rhoiney; Roderick Claybrooks
Journal:  Turk Neurosurg       Date:  2015       Impact factor: 1.003

Review 2.  Axial (spinal) gout.

Authors:  Elena Lumezanu; Rukmini Konatalapalli; Arthur Weinstein
Journal:  Curr Rheumatol Rep       Date:  2012-04       Impact factor: 4.592

3.  Gout in the cervical spine: MR pattern mimicking diskovertebral infection.

Authors:  T P Duprez; J Malghem; B C Vande Berg; H M Noel; E A Munting; B E Maldague
Journal:  AJNR Am J Neuroradiol       Date:  1996-01       Impact factor: 3.825

4.  Spinal gout: case report and review of the literature.

Authors:  Mirela Draganescu; Lawrence J Leventhal
Journal:  J Clin Rheumatol       Date:  2004-04       Impact factor: 3.517

Review 5.  Tophaceous gout of the spine in a patient with no peripheral tophi: case report and review of the literature.

Authors:  J Varga; C Giampaolo; D L Goldenberg
Journal:  Arthritis Rheum       Date:  1985-11

6.  Prevalence of gout and hyperuricemia in the US general population: the National Health and Nutrition Examination Survey 2007-2008.

Authors:  Yanyan Zhu; Bhavik J Pandya; Hyon K Choi
Journal:  Arthritis Rheum       Date:  2011-10

7.  Tophaceous gout of the lumbar spine mimicking a spinal meningioma.

Authors:  Pedro Ribeiro da Cunha; António Judice Peliz; Marcos Barbosa
Journal:  Eur Spine J       Date:  2016-11-05       Impact factor: 3.134

Review 8.  Tophaceous gout of the spine mimicking epidural infection: case report and review of the literature.

Authors:  K Barrett; M L Miller; J T Wilson
Journal:  Neurosurgery       Date:  2001-05       Impact factor: 4.654

9.  Tophaceous gout of the thoracic spine presenting as back pain and fever.

Authors:  R Hausch; M Wilkerson; E Singh; C Reyes; T Harrington
Journal:  J Clin Rheumatol       Date:  1999-12       Impact factor: 3.517

Review 10.  Gout in the Spine: Imaging, Diagnosis, and Outcomes.

Authors:  Michael Toprover; Svetlana Krasnokutsky; Michael H Pillinger
Journal:  Curr Rheumatol Rep       Date:  2015-12       Impact factor: 4.592

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  1 in total

1.  Acute presentation of spinal gouty arthritis: A case report and review of literature.

Authors:  Asad S Akhter; Ahmed Mohyeldin; Andrew J Grossbach
Journal:  Surg Neurol Int       Date:  2019-11-29
  1 in total

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