Literature DB >> 27817138

Tophaceous gout of the lumbar spine mimicking a spinal meningioma.

Pedro Ribeiro da Cunha1, António Judice Peliz2, Marcos Barbosa2.   

Abstract

PURPOSE: Although gout is a common metabolic disorder, it usually affects distal joints of the appendicular skeleton. Axial spine involvement is rare, with only 131 cases reported in the literature. The authors report a rare case of lumbar spinal gout mimicking a spinal meningioma.
METHODS: A 77-year-old man with a history of gout presented with chronic low back pain and progressive paraparesis. Imaging revealed a lumbar spine compressive mass lesion with a dural tail signal. The differential diagnosis was thought to be straightforward favoring a spinal meningioma. Tophaceous gout was never considered. The presence of a dural tail associated with the lesion is an interesting detail of this case, that strongly misguided it and to the best of our knowledge it is the first one reported in the literature.
RESULTS: The patient underwent surgery and intra-operative findings were surprisingly different from those expected, revealing a chalky white mass lesion firmly adherent and compressing the dural sac. It was completely excised, leaving the dura intact. Histopathology confirmed the diagnosis of tophaceous gout. The patient was sent to physical therapy and had a complete remission of pain and neurological deficit, regaining his walking capacity.
CONCLUSION: Although spinal gout is rare, it should be considered in the differential diagnosis for patients presenting with symptoms of spinal stenosis, a suspicion of neoplastic lesion of the spine, and a previous history of gout. Early diagnosis can ensure proper and timely medical management, perhaps avoiding neurological compromise and the need for surgery.

Entities:  

Keywords:  Low back pain; Lumbar spine; Spinal meningioma; Tophaceous gout

Mesh:

Year:  2016        PMID: 27817138     DOI: 10.1007/s00586-016-4831-7

Source DB:  PubMed          Journal:  Eur Spine J        ISSN: 0940-6719            Impact factor:   3.134


  12 in total

1.  Pathologic changes in gout; survey of eleven necropsied cases.

Authors:  M H LEVIN; L LICHTENSTEIN; H W SCOTT
Journal:  Am J Pathol       Date:  1956 Sep-Oct       Impact factor: 4.307

Review 2.  Tophaceous Gout of the Lumbar Spine: Case Report and Review of the Literature.

Authors:  Andrey Volkov; David L Rhoiney; Roderick Claybrooks
Journal:  Turk Neurosurg       Date:  2015       Impact factor: 1.003

Review 3.  Gouty arthropathy of the lumbar spine: a case report and review of the literature.

Authors:  J C King; C Nicholas
Journal:  Spine (Phila Pa 1976)       Date:  1997-10-01       Impact factor: 3.468

4.  Tophaceous gout of the lumbar spine mimicking an epidural abscess: MR features.

Authors:  V M Bonaldi; H Duong; M R Starr; L Sarazin; J Richardson
Journal:  AJNR Am J Neuroradiol       Date:  1996 Nov-Dec       Impact factor: 3.825

Review 5.  Spinal gout in a renal transplant patient: a case report and literature review.

Authors:  Lewis C Hou; Andrew R Hsu; Anand Veeravagu; Maxwell Boakye
Journal:  Surg Neurol       Date:  2006-10-06

6.  Cervical gout.

Authors:  S Sabharwal; T Gibson
Journal:  Br J Rheumatol       Date:  1988-10

7.  Topacheous gout as a rare cause of spinal stenosis in the lumbar region. Case report.

Authors:  Joseph Kelly; Chris Lim; Mahmoud Kamel; Catherine Keohane; Michael O'Sullivan
Journal:  J Neurosurg Spine       Date:  2005-02

Review 8.  Gout in the Spine: Imaging, Diagnosis, and Outcomes.

Authors:  Michael Toprover; Svetlana Krasnokutsky; Michael H Pillinger
Journal:  Curr Rheumatol Rep       Date:  2015-12       Impact factor: 4.592

Review 9.  Gout.

Authors:  Pascal Richette; Thomas Bardin
Journal:  Lancet       Date:  2009-08-17       Impact factor: 79.321

Review 10.  Axial gouty arthropathy.

Authors:  Lesley Ann Saketkoo; Hugh J Robertson; Herbert R Dyer; Zia-Ullah Virk; Humberto Roque Ferreyro; Luis R Espinoza
Journal:  Am J Med Sci       Date:  2009-08       Impact factor: 2.378

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  7 in total

1.  A primary meningioma of the lumbar spine with neck metastasis.

Authors:  Chih-Wei Sung; Kevin Li-Chun Hsieh; Yi-Jie Kuo
Journal:  J Spinal Cord Med       Date:  2019-01-09       Impact factor: 1.985

2.  Expert's comment concerning Grand Rounds case entitled "Tophaceous gout of the lumbar spine mimicking a spinal meningioma" by Pedro Ribeiro da Cunha Ferreira, António Judice Peliz, and Marcos Barbosa (Eur Spine J, 2016; DOI 10.1007/s00586-016-4831-7).

Authors:  Heba Ibrahim Ali
Journal:  Eur Spine J       Date:  2016-11-17       Impact factor: 3.134

3.  The Michel Benoist and Robert Mulholland Yearly European Spine Journal Review: A survey of the "medical" articles in the European Spine Journal, 2018.

Authors:  Michel Benoist
Journal:  Eur Spine J       Date:  2019-01-02       Impact factor: 3.134

4.  Rogue one: a story of tophaceous gout in the spine.

Authors:  Karthik Dwarki; Andy Dothard; Bryan Abadie; Matthew C Miles
Journal:  BMJ Case Rep       Date:  2018-04-17

5.  Mimicking Meningismus: A Case of Atlantoaxial Gout.

Authors:  Johnathon Gorman; Andrew Van Der Westhuizen; Sadia Raheez Qamar; Clark Funnell
Journal:  Neurol Clin Pract       Date:  2021-06

6.  Tophaceous gout causing lumbar stenosis: A case report.

Authors:  Huigen Lu; Jianming Sheng; Jiaping Dai; Xuqi Hu
Journal:  Medicine (Baltimore)       Date:  2017-08       Impact factor: 1.889

7.  Gout Storm.

Authors:  Danilo Martins; Carolina Rodrigues Tonon; Rafael Lopes Pacca; Natanye Lemes Matchil; Luiz Antonio Jorge Junior; Dênis Silva Queiroz; Filipe Welson Leal Pereira; Alana Maia Silva; Vinicius Padovese; Marcelo Padovani de Toledo Moraes; Daniel Luiz da Silva; Vinicius Cardoso Nóbrega; Emilio Carlos Curcelli; Marina Politi Okoshi
Journal:  Am J Case Rep       Date:  2021-09-20
  7 in total

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