T Harata1, Maki Goto2,3, A Iwase2,3, S Kurotsuchi3, H Ando4, M Osawa5, A Sugita3, M Kondo3, T Nakamura3, T Nakahara3, S Takikawa3, S Manabe3, F Kikkawa2,3. 1. Department of Maternal and Perinatal Medicine Toyota Memorial Hospital 1-1 Heiwa-cho Toyota Japan. 2. Department of Maternal and Perinatal Medicine Nagoya University Graduate School of Medicine Nagoya Japan. 3. Department of Obstetrics and Gynecology Nagoya University Graduate School of Medicine 65 Tsurumai-cho, Showa-ku 466-8550 Nagoya Japan. 4. Center for Reproductive Medicine, Toyohashi Municipal Hospital 50 Hachiken Nishi, Aotake-cho Toyohashi Japan. 5. Narita Hospital 1-20-30 Osu, Naka-ku Nagoya Japan.
Abstract
Purpose: This study evaluated the changes in psychological stress during in vitro fertilization and embryo transfer (IVF-ET) and the relationship of such stress to the patients' background and gender. Methods: Sixty couples undergoing IVF-ET were administered the State-Trait Anxiety Inventory-JYZ (STAI) test at six different points during IVF-ET procedures. Anxiety scores at each time point were recorded and analyzed according to gender, fertility status, and duration of treatment. Results: The median state anxiety score for women increased following induction until oocyte collection, after which it temporarily declined and then increased again until the pregnancy test. No such changes were noted in men. Scores for women who had undergone a shorter period of IVF treatments were higher while state and trait anxiety in men increased with a prolonged treatment period. Unsuccessful treatment increased the state and trait anxiety of women. Conclusions: Psychological stress changed periodically depending on the duration of the patients' treatment and fertility status also influenced anxiety levels. These findings will prove helpful in guiding psychological therapy and counseling for couples attempting to conceive by in vitro fertilization.
Purpose: This study evaluated the changes in psychological stress during in vitro fertilization and embryo transfer (IVF-ET) and the relationship of such stress to the patients' background and gender. Methods: Sixty couples undergoing IVF-ET were administered the State-Trait Anxiety Inventory-JYZ (STAI) test at six different points during IVF-ET procedures. Anxiety scores at each time point were recorded and analyzed according to gender, fertility status, and duration of treatment. Results: The median state anxiety score for women increased following induction until oocyte collection, after which it temporarily declined and then increased again until the pregnancy test. No such changes were noted in men. Scores for women who had undergone a shorter period of IVF treatments were higher while state and trait anxiety in men increased with a prolonged treatment period. Unsuccessful treatment increased the state and trait anxiety of women. Conclusions: Psychological stress changed periodically depending on the duration of the patients' treatment and fertility status also influenced anxiety levels. These findings will prove helpful in guiding psychological therapy and counseling for couples attempting to conceive by in vitro fertilization.
Authors: Minden B Sexton; Michelle R Byrd; William T O'Donohue; Negar Nicole Jacobs Journal: Arch Womens Ment Health Date: 2010-02-02 Impact factor: 3.633