Literature DB >> 29661756

Prevention of rickets and osteomalacia in the UK: political action overdue.

Suma Uday1,2, Wolfgang Högler1,2.   

Abstract

The consequences of vitamin D and dietary calcium deficiency have become a huge public health concern in the UK. The burden of disease from these deficiencies includes rickets, and hypocalcaemic seizures, dilated cardiomyopathy and mostly occult myopathy and osteomalacia. The increasing burden of the disease is intrinsically linked to ethnicity and the population demographic changes in the UK. Three facts have led to the resurfacing of the English disease: (1) the UK has no ultraviolet sunlight for at least 6 months of the year, (2) dark skin produces far less vitamin D than white skin per unit ultraviolet light exposure, and (3) non-European Union immigration over the last century. To date, the UK government demonstrates incomplete understanding of these three facts, and its failure to adjust its prevention programmes to changing demographics is endangering the health and life of UK residents with dark skin, of whom infants are the most vulnerable. Establishing accountability through the implementation of monitored antenatal and infantile supplementation programmes and mandatory food fortification is overdue. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Entities:  

Keywords:  African; South Asian; dark skin; immigration; vitamin D deficiency

Mesh:

Substances:

Year:  2018        PMID: 29661756     DOI: 10.1136/archdischild-2018-314826

Source DB:  PubMed          Journal:  Arch Dis Child        ISSN: 0003-9888            Impact factor:   3.791


  12 in total

Review 1.  Vitamin D history part III: the "modern times"-new questions for orthopaedic practice: deficiency, cell therapy, osteomalacia, fractures, supplementation, infections.

Authors:  Philippe Hernigou; Jordan Sitbon; Arnaud Dubory; Jean Charles Auregan
Journal:  Int Orthop       Date:  2019-04-29       Impact factor: 3.075

Review 2.  Skeletal and Extraskeletal Actions of Vitamin D: Current Evidence and Outstanding Questions.

Authors:  Roger Bouillon; Claudio Marcocci; Geert Carmeliet; Daniel Bikle; John H White; Bess Dawson-Hughes; Paul Lips; Craig F Munns; Marise Lazaretti-Castro; Andrea Giustina; John Bilezikian
Journal:  Endocr Rev       Date:  2019-08-01       Impact factor: 19.871

3.  Population-Based Incidence of Potentially Life-Threatening Complications of Hypocalcemia and the Role of Vitamin D Deficiency.

Authors:  Andrea J Aul; Philip R Fischer; Jason S O'Grady; Kristin C Mara; Julie A Maxson; Alicia M Meek; Tanya M Petterson; Tom D Thacher
Journal:  J Pediatr       Date:  2019-04-04       Impact factor: 4.406

4.  Serum 25-hydroxyvitamin D response to vitamin D supplementation in infants: a systematic review and meta-analysis of clinical intervention trials.

Authors:  Armin Zittermann; Stefan Pilz; Heiner K Berthold
Journal:  Eur J Nutr       Date:  2019-02-05       Impact factor: 5.614

Review 5.  Vitamin D: Nutrient, Hormone, and Immunomodulator.

Authors:  Francesca Sassi; Cristina Tamone; Patrizia D'Amelio
Journal:  Nutrients       Date:  2018-11-03       Impact factor: 5.717

6.  Cardiac, bone and growth plate manifestations in hypocalcemic infants: revealing the hidden body of the vitamin D deficiency iceberg.

Authors:  Suma Uday; Nadja Fratzl-Zelman; Paul Roschger; Klaus Klaushofer; Ashish Chikermane; Vrinda Saraff; Ted Tulchinsky; Tom D Thacher; Tamas Marton; Wolfgang Högler
Journal:  BMC Pediatr       Date:  2018-06-26       Impact factor: 2.125

7.  We still don't know that our children need vitamin D daily: a study of parents' understanding of vitamin D requirements in children aged 0-2 years.

Authors:  Rhiannon Eleanor Day; Roxane Krishnarao; Pinki Sahota; Meaghan Sarah Christian
Journal:  BMC Public Health       Date:  2019-08-15       Impact factor: 3.295

8.  Vitamin D status of children with paediatric inflammatory multisystem syndrome temporally associated with severe acute respiratory syndrome coronavirus 2 (PIMS-TS).

Authors:  Suma Uday; Deepthi Jyothish; Angeline Darren; Meissa Osman; Kavitha Masilamani; Syed Habib Ali; Hari Krishnan Kanthimathinathan; Ashish Chikermane; Eslam Al-Abadi; Steven B Welch; Scott Hackett; Barnaby R Scholefield
Journal:  Br J Nutr       Date:  2021-05-12       Impact factor: 3.718

9.  Is a vitamin D fortification strategy needed?

Authors:  J L Buttriss; S A Lanham-New
Journal:  Nutr Bull       Date:  2020-05-18

Review 10.  Vitamin D Signaling in Inflammation and Cancer: Molecular Mechanisms and Therapeutic Implications.

Authors:  Ahmed El-Sharkawy; Ahmed Malki
Journal:  Molecules       Date:  2020-07-15       Impact factor: 4.411

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.