Satoshi Tsutsumi1, Hideo Ono2, Hisato Ishii3, Yukimasa Yasumoto3. 1. Department of Neurological Surgery, Juntendo University Urayasu Hospital, 2-1-1 Tomioka, Urayasu, Chiba, 279-0021, Japan. shotaro@juntendo-urayasu.jp. 2. Division of Radiological Technology, Medical Satellite Yaesu Clinic, Tokyo, Japan. 3. Department of Neurological Surgery, Juntendo University Urayasu Hospital, 2-1-1 Tomioka, Urayasu, Chiba, 279-0021, Japan.
Abstract
PURPOSE: The morphological relationships between the periventricular Virchow-Robin spaces (VRSs) and cerebral ventricles have been poorly documented. The present study aimed to explore the issue using magnetic resonance imaging. METHODS: A total of 211 patients were included in this study. T2-weighted and constructive interference in steady state (CISS) sequences were performed in thin-sliced, coronal sections. RESULTS: On T2-weighted sequence, the periventricular VRSs with ependymal openings were identified in 34% of 139 subjects. All the openings were located in the lateral wall of the anterior horn. In CISS sequences, such VRSs were found in 39% of 72 subjects. The mean age was significantly higher in the population with such VRSs compared to those without VRSs (p = 0.0047). Of the 58 periventricular VRSs with ependymal openings identified on T2-weighted images, 16% were located in the upper, 36% in the middle, and 48% in the lower part of the lateral wall. Of the 38 such VRSs identified on CISS images, 32% were located in the upper, 24% in the middle, and 42% in the lower part of the lateral wall, and 3% in the upper part of the medial wall. CONCLUSIONS: The ependymal openings of the periventricular VRSs may be centered in the lateral wall of the anterior horn. The coronal CISS sequence can sensitively delineate the VRSs with ependymal openings.
PURPOSE: The morphological relationships between the periventricular Virchow-Robin spaces (VRSs) and cerebral ventricles have been poorly documented. The present study aimed to explore the issue using magnetic resonance imaging. METHODS: A total of 211 patients were included in this study. T2-weighted and constructive interference in steady state (CISS) sequences were performed in thin-sliced, coronal sections. RESULTS: On T2-weighted sequence, the periventricular VRSs with ependymal openings were identified in 34% of 139 subjects. All the openings were located in the lateral wall of the anterior horn. In CISS sequences, such VRSs were found in 39% of 72 subjects. The mean age was significantly higher in the population with such VRSs compared to those without VRSs (p = 0.0047). Of the 58 periventricular VRSs with ependymal openings identified on T2-weighted images, 16% were located in the upper, 36% in the middle, and 48% in the lower part of the lateral wall. Of the 38 such VRSs identified on CISS images, 32% were located in the upper, 24% in the middle, and 42% in the lower part of the lateral wall, and 3% in the upper part of the medial wall. CONCLUSIONS: The ependymal openings of the periventricular VRSs may be centered in the lateral wall of the anterior horn. The coronal CISS sequence can sensitively delineate the VRSs with ependymal openings.